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Fabrication d’anisotrope polymères artificiels cellules présentatrices d’Activation des cellules T CD8 +
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1Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology,Johns Hopkins University School of Medicine, 2Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy,Johns Hopkins University School of Medicine
Chapters
- 00:04Title
- 00:49Tunable Spherical Poly(Lactic-Co-Glycolic Acid) (PLGA) Fabrication
- 03:30Tunable Polymeric Particle Fabrication
- 06:21Surface Protein Conjugation for Artificial Antigen Presenting Cell (aAPC) Creation
- 08:01Results: Representative Spherical and Ellipsoidal Particle Characterization
- 09:49Conclusion
Nous présentons ici un protocole pour générer rapidement et de façon reproductible des inspirée, biodégradable articifical cellules présentatrices (VAMP) avec taille ajustable, forme et présentation de la protéine de surface des lymphocytes T expansion ex vivo ou in vivo .
