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Non-invasive Assessment of Dorsiflexor Muscle Function in Mice
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Medicine
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JoVE Journal Medicine
Non-invasive Assessment of Dorsiflexor Muscle Function in Mice

Non-invasive Assessment of Dorsiflexor Muscle Function in Mice

DOI:
10.3791/58696-v

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05:31 min

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January 17, 2019

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, , , , , ,
1School of Exercise and Nutrition Sciences,Deakin University, 2Centre for Molecular and Medical Research, School of Medicine,Deakin University, 3Department of Orthopaedics, School of Medicine,University of Maryland, 4Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences,Deakin University, 5Department of Physiology, Anatomy and Microbiology,La Trobe University

Chapters

  • 00:04Title
  • 00:51Experimental Setup
  • 01:52Animal Preparation
  • 02:46Optimization of the Electrodes Position
  • 04:34Results: Representative Force Frequency Curve
  • 05:11Conclusion

Summary

Automatic Translation

Automatic Translation

Measurement of rodent skeletal muscle contractile function is a useful tool that can be used to track disease progression as well as efficacy of therapeutic intervention. We describe here the non-invasive, in vivo assessment of the dorsiflexor muscles that can be repeated over time in the same mouse.

Tags

Dorsiflexor Muscle FunctionNon-invasive AssessmentMiceMuscle Contraction FunctionDisease ProgressionVisual DemonstrationMouse Knee ClampMouse FootplateTransducerDynamic Muscle Control SoftwareAutosaveSequencerIsofluranePeroneal NerveDorsiflexion Torque

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