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Use of In Vivo Single-fiber Recording and Intact Dorsal Root Ganglion with Attached Sciatic Nerve to Examine the Mechanism of Conduction Failure
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1Department of Neurobiology, School of Basic Medicine,Fourth Military Medical University, 2Department of Toxicology, School of Public Health,ShanXi Medical University, 3Department of Psychology,Fourth Military Medical University, 4Department of Neurobiology, School of Basic Medical Sciences, Advanced Innovation Center for Human Brain Protection,Capital Medical University, 5Neuroscience Research Institute, Key Lab for Neuroscience, Ministry of Education/National Health Commission,Peking University, 6Department of Radiation Biology, Faculty of Preventive Medicine,Fourth Military Medical University
Chapters
- 00:04Title
- 01:13In Vivo Single-fiber Recording
- 04:16Preparation of Intact DRG Attached with Sciatic Nerve
- 07:48Results: Attenuation of Conduction Failure in CFA-treated Rats and Exploration of AHP Property
- 08:55Conclusion
Single-fiber recording is an effective electrophysiological technique that is applicable to the central and peripheral nervous systems. Along with the preparation of intact DRG with the attached sciatic nerve, the mechanism of conduction failure is examined. Both protocols improve the understanding of the peripheral nervous system's relationship with pain.
