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A entrega electrophoretic do ácido γ-aminobutyric (GABA) no foco epileptic impede apreensões nos ratos
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1Aix Marseille Université, Institut de Neurosciences des Systèmes (INS), 2Electrical Engineering Division,University of Cambridge, 3Department of Bioelectronics,Centre Microélectronique de Provence – Ecole Nationale Supérieure des Mines de Saint-Étienne (CMP-EMSE), 4Institut de Neurosciences de la Timone,Centre National de la Recherche Scientifique (CNRS) UMR 7289 & Aix- Marseille Université, 5Neuroengineering Research Group, Interdisciplinary Excellence Center, Department of Medical Microbiology and Immunobiology,University of Szeged
Chapters
- 00:04Title
- 00:56Craniotomy
- 02:23Multichannel Silicon Probe and Microfluidic Ion Pump (μFIP) Insertion
- 04:23Seizure Induction
- 05:26Results: Representative Multichannel Recording and Seizure Response Analysis
- 06:26Conclusion
O desafio da pesquisa da epilepsia é desenvolver tratamentos novos para os pacientes onde a terapia clássica é inadequada. Usando um protocolo novo — com a ajuda de um sistema implantáveis da entrega da droga — nós podemos controlar apreensões em ratos anestesiados pela entrega electrophoretic de GABA no foco epileptic.
