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[11C_SNAP-7941] 自动合成和实时动力学评估的技术方面
JoVE Journal
Chemistry
This content is Free Access.
JoVE Journal Chemistry
Technical Aspect of the Automated Synthesis and Real-Time Kinetic Evaluation of [11C]SNAP-7941
DOI:

09:50 min

April 28, 2019

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Chapters

  • 00:04Title
  • 01:20Automated Synthesis of [11C]SNAP-7941 for Preclinical Use
  • 04:40Quality Control (QC) of [11C]SNAP-7941
  • 05:55Real-Time Kinetic Assay
  • 08:02Results: Evaluation of [11C]SNAP-7941 Interactions Towards the Permeability Glycoprotein 1 (P-gp) Transporter
  • 08:44Conclusion

Summary

Automatic Translation

在这里,我们代表一个协议,用于对[11C_SNAP-7941 的全自动无线电标记,以及此 PET 跟踪器在 P-gp 表达和非表达细胞上的实时动力学分析。

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