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通过物理和各向异性扩张对人体组织部分的纳米成像
JoVE Journal
Medicine
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JoVE Journal Medicine
Nanoscopic Imaging of Human Tissue Sections via Physical and Isotropic Expansion
DOI:

09:11 min

September 25, 2019

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Chapters

  • 00:05Title
  • 01:19Preparation of Archived and Freshly Prepared Clinical Tissue Slides for ExPath
  • 04:05In Situ Polymerization of Specimens
  • 05:16Sample Digestion and Imaging
  • 06:40Results: Multicolor Super-resolution Tissue Imaging using Expansion Pathology
  • 08:18Conclusion

Summary

Automatic Translation

临床组织样本的纳米成像可以增进对疾病发病机制的认识。扩张病理学 (ExPath) 是扩展显微镜 (ExM) 的一个版本,经过修改,与标准临床组织样本兼容,使用传统的衍射受限显微镜探索生物分子的纳米级配置。

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