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分析肿瘤基因表达因子与CorExplorer门户网站
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
Analyzing Tumor Gene Expression Factors with the CorExplorer Web Portal
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分析肿瘤基因表达因子与CorExplorer门户网站

DOI:
10.3791/60431-v

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08:00 min

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October 11, 2019

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, ,
1Lyrid LLC, 2Independent consultant, 3Information Sciences Institute,University of Southern California

Chapters

  • 00:04Title
  • 00:41Exploring Factors Containing a Gene of Interest
  • 03:06Filtering and Interpreting CorEx Factors and Finding Commonalities and Differences of Gene Expression Variation Across Tumor Types
  • 05:49Results: Representative Tumor Gene Expression Factor Analysis
  • 07:31Conclusion

Summary

Automatic Translation

Automatic Translation

我们介绍了CorExplorer门户网站，一种用于探索机器学习算法CorEx（相关解释）发现的肿瘤RNA测序因子的资源，并展示了如何分析与生存、数据库注释相关的因素，蛋白质-蛋白质相互作用，彼此深入了解肿瘤生物学和治疗干预。

Tags

CorExplorerTumor Gene ExpressionInformation MaximizationLatent FactorsCancer BiologyTCGALung CancerRNA SequencingFactor GraphGene ExpressionBiological DiscoveryGene-factor Associations

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