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심근 기계 변형의 변위 분석 (DIAMOND) 배아 제브라피시에 있는 심장 기능의 분할 이질성을 제시합니다
JoVE Journal
Developmental Biology
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JoVE Journal Developmental Biology
Displacement Analysis of Myocardial Mechanical Deformation (DIAMOND) Reveals Segmental Heterogeneity of Cardiac Function in Embryonic Zebrafish
DOI:

09:15 min

February 06, 2020

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Chapters

  • 00:04Introduction
  • 01:13Reconstruction of the 3D Systolic and Diastolic Heart and Segmentation of the Ventricle
  • 02:41Creation of Rectangular Parallelepipeds for Image Registration and Resampling of Systolic and Diastolic 3D Hearts Along the Short Axis Plane
  • 05:01Division of the Resampled Heart
  • 06:20Registration of Systolic and Diastolic Image Matrices and Output of Displacement Vectors
  • 07:01Results: Segmental Heterogeneity in Cardiac Function and Susceptibility to Chemotherapy-induced Injury
  • 08:45Conclusion

Summary

Automatic Translation

이 프로토콜의 목적은 생리적 및 병리학적 조건 모두에서 배아 제브라피시의 분절 심장 기능 평가를 위한 새로운 방법을 자세히 설명하는 것입니다.

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