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Injection of Hydrogel Biomaterial Scaffolds to The Brain After Stroke
 

Injection of Hydrogel Biomaterial Scaffolds to The Brain After Stroke

Article DOI: 10.3791/61450-v • 09:41 min • October 1st, 2020
October 1st, 2020 •
1, 2, 1,3,4
1Department of Biomedical Engineering, Duke University, 2Department of Neurology, University of California Los Angeles, 3Department of Neurology, Duke University, 4Department of Dermatology, Duke University

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Summary
Automatic Translation

Stroke is a global issue with minimal treatment options and no current clinical therapy for regenerating the lost brain tissue. Here we describe methods for creating precise photothrombotic stroke in the motor cortex of rodents and subsequent injection of hydrogel biomaterials to study their effects on tissue regeneration after stroke.

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Keywords: Hydrogel Biomaterial Scaffold Stroke Photothrombotic Stroke Model Rose Bengal Dye Laser Motor Cortex Behavioral Readout Biopolymer Hydrogel Brain Repair Brain Regeneration
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