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Murine Excisional Wound Healing Model and Histological Morphometric Wound Analysis
JoVE Journal
Developmental Biology
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JoVE Journal Developmental Biology
Murine Excisional Wound Healing Model and Histological Morphometric Wound Analysis
DOI:

06:36 min

August 21, 2020

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Chapters

  • 00:04Introduction
  • 00:33Skin Preparation
  • 01:16Wound Induction
  • 02:16Morphometric Analysis
  • 05:01Results: Whole Wound Histological Morphometric Analyses
  • 05:54Conclusion

Summary

Automatic Translation

This protocol describes how to generate bilateral, full-thickness excisional wounds in mice and how to subsequently monitor, harvest, and prepare the wounds for morphometric analysis. Included is an in-depth description of how to use serial histological sections to define, precisely quantify and detect morphometric defects.

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