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Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
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JoVE Journal Behavior
Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

DOI:
10.3791/61806-v

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07:41 min

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October 23, 2020

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, , , , , ,
1Center for Visual and Neurocognitive Rehabilitation,Atlanta VA Medical Center, 2Department of Biomedical Engineering,Georgia Institute of Technology, 3Department of Neuroscience,Emory University, 4Gangarosa Department of Environmental Health,Emory University

Chapters

  • 00:04Introduction
  • 01:01Optomotor Response (OMR) Apparatus Setup
  • 02:24Spatial Frequency Evaluation
  • 03:51Contrast Sensitivity Evaluation
  • 04:41Y-Maze Evaluation
  • 05:54Results: Representative OMR and Y-Maze Analyses of Diabetic Rat Visual and Cognitive Function and Exploratory Behavior Over Time
  • 07:05Conclusion

Summary

Automatic Translation

Automatic Translation

Neural degeneration in both eyes and brain as a result of diabetes can be observed through behavioral tests carried out on rodents. The Y-maze, a measure of spatial cognition, and the optomotor response, a measure of visual function, both provide insight into potential diagnoses and treatments.

Tags

Optomotor ResponseY-mazeBehavioral AssessmentVisual FunctionCognitive FunctionDiabetesRodentSpatial FrequencyVirtual Reality

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