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Finite Element Modelling of a Cellular Electric Microenvironment
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Finite Element Modelling of a Cellular Electric Microenvironment

Finite Element Modelling of a Cellular Electric Microenvironment

DOI:
10.3791/61928-v

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08:23 min

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May 18, 2021

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, , , ,
1Department of Materials, Faculty of Science and Engineering,The University of Manchester, 2Department of Mechanical, Aerospace and Civil Engineering, Faculty of Science and Engineering,The University of Manchester, 3The Henry Royce Institute, Royce Hub Building,The University of Manchester

Chapters

  • 00:04Introduction
  • 00:44Build the Model in COMSOL
  • 03:57Perform Simulation
  • 05:12Analysis
  • 06:38Results: Influence of Fiber Alignment on Electric Field
  • 07:42Conclusion

Summary

Automatic Translation

Automatic Translation

This paper presents a strategy for building finite element models of fibrous conductive materials exposed to an electric field (EF). The models can be used to estimate the electrical input that cells seeded in such materials receive and assess the impact of changing the scaffold's constituent material properties, structure or orientation.

Tags

Keywords: Finite Element ModelingCellular Electric MicroenvironmentExtracellular MatrixElectrical StimulationCOMSOLMaterial PropertiesElectrical ConductivityRelative Permittivity3D ModelingParameter OptimizationElectric Current ModuleBoundary Conditions

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