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1Cardiovascular and Metabolic Sciences, Lerner Research Institute; Women’s Health Institute,Cleveland Clinic, 2Women’s Health Institute,Cleveland Clinic, 3Department of Obstetrics and Gynecology, 983255 Nebraska Medical Center,University of Nebraska Medical Center, 4Anatomic Pathology,Cleveland Clinic, 5Gynecologic Oncology, Women’s Health Institute and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine,Cleveland Clinic
Chapters
- 00:04Introduction
- 00:53Donor and Recipient Mouse Preparation and Donor Mouse Endometrial Tissue Harvest
- 02:59Peritoneal Tissue Fragment Injection
- 04:03Endometriotic Lesion Harvest
- 04:51Endometriotic Lesion Scoring
- 05:58Results: Representative Endometriosis Lesion Histopathological Analyses
- 06:39Conclusion
Endometriozisin birçok kemirgen modeli teknik karmaşıklık, tekrarlanabilirlik ve / veya bağışıklığı baskılanmış hayvanlara veya özel muhabir farelere ihtiyaç duyma ile sınırlıdır. Bağımsız olarak doğrulanabilir, objektif puanlama sistemine sahip ve ovaerektomi veya sağkalım ameliyatı için gereklilik olmayan herhangi bir deneysel fare kullanarak basitleştirilmiş bir lezyon indüksiyon sistemi sunuyoruz.
