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A Proinflammatory, Degenerative Organ Culture Model to Simulate Early-Stage Intervertebral Disc Disease.
JoVE Journal
Medicine
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JoVE Journal Medicine
A Proinflammatory, Degenerative Organ Culture Model to Simulate Early-Stage Intervertebral Disc Disease.
DOI:

05:46 min

February 14, 2021

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Chapters

  • 00:04Introduction
  • 00:38Dissection of the Bovine Intervertebral Disc
  • 02:27IVD Culture and Loading
  • 03:36Intradiscal TNF-α Injection
  • 04:13Results: Assessment of Intervertebral Disc Degeneration Caused by Degenerative Loading, Limited Nutrition, and TNF-α Injection
  • 04:59Conclusion

Summary

Automatic Translation

Este protocolo presenta un modelo experimental nuevo de la cultura proinflamatoria, degenerativa del órgano bovino para simular la degeneración intervertebral del disco de la temprano-etapa.

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