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Formulation and Acoustic Modulation of Optically Vaporized Perfluorocarbon Nanodroplets
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Bioengineering
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JoVE Journal Bioengineering
Formulation and Acoustic Modulation of Optically Vaporized Perfluorocarbon Nanodroplets

Formulation and Acoustic Modulation of Optically Vaporized Perfluorocarbon Nanodroplets

DOI:
10.3791/62814-v

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07:44 min

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July 16, 2021

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, ,
1Department of Biomedical Engineering,Georgia Institute of Technology and Emory University, 2School of Electrical Engineering,Georgia Institute of Technology, 3Department of Biomedical Engineering and School of Electrical Engineering,Georgia Institute of Technology and Emory University

Chapters

  • 00:05Introduction
  • 00:30Perfluorocarbon Nanodroplet Formulation
  • 03:12Polyacrylamide Phantom Preparation
  • 05:07Perfluorocarbon Nanodroplet Imaging
  • 06:21Results: Acoustic Modulation of Optically Vaporized Perfluorocarbon Nanodroplets
  • 07:20Conclusion

Summary

Automatic Translation

Automatic Translation

Optically activated perfluorocarbon nanodroplets show promise in imaging applications outside of the vascular system. This article will demonstrate how to synthesize these particles, crosslink polyacrylamide phantoms, and modulate the droplets acoustically to enhance their signal.

Tags

Perfluorocarbon NanodropletsDSPE-mPEG-2000DSPCIR-1048Probe SonicationCentrifugationAcoustic ModulationContrast EnhancementUltrasound Imaging

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