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A Modified Simple Method for Induction of Myocardial Infarction in Mice
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A Modified Simple Method for Induction of Myocardial Infarction in Mice

A Modified Simple Method for Induction of Myocardial Infarction in Mice

DOI:
10.3791/63042-v

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04:29 min

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December 03, 2021

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, , , , ,
1Department of Cardiology,The First Affiliated Hospital of Bengbu Medical College, 2Department of Cardiology, Ren Ji Hospital, School of Medicine,Shanghai Jiao Tong University

Chapters

  • 00:05Introduction
  • 00:44Operative Preparation
  • 01:12Induction of Myocardial Infarction
  • 02:13Harvesting the Tissue
  • 03:08Results: Induction of Myocardial Infarction in Mice
  • 03:48Conclusion

Summary

Automatic Translation

Automatic Translation

Under adequate anesthesia, the mouse heart was externalized through the intercostal space, and myocardial infarction was successfully induced by ligating the left anterior descending artery (LAD) using materials readily available in most laboratories.

Tags

Keywords: Myocardial InfarctionMouse ModelSurgical ProcedureTTC StainingPost-MI RemodelingCoronary Artery LigationHeart Slicing

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