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Chapters
- 00:04Introduction
- 00:52Jugular Vein Isolation
- 02:29Jugular Vein Cannulation
- 04:09Catheter Exteriorization
- 05:41Physiological and Hematological Monitoring During Recovery Phase
- 06:41Results: Physiological-Hematological Monitoring and Pharmacokinetics of Ellagic Acid in Jugular Vein Cannulation (JVC) Rat Model
- 07:48Conclusion
Detaljerede mikrokirurgiske teknikker er demonstreret for at etablere en langsigtet jugular vene kanylering rotte model for sekventiel blodopsamling i samme dyr. Fysiologiske og hæmatologiske parametre er blevet overvåget i rottens genopretningsfase. Denne model er blevet anvendt til at studere farmakokinetik af oralt administreret polyphenol uden at fremkalde dyrestress.
