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小鼠脑切片上淀粉样蛋白-β负荷的全区域与亚区域定量
JoVE Journal
Neuroscience
This content is Free Access.
JoVE Journal Neuroscience
Full- versus Sub-Regional Quantification of Amyloid-Beta Load on Mouse Brain Sections
DOI:

07:28 min

May 19, 2022

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Chapters

  • 00:05Introduction
  • 00:42Full-Region of Interest (ROI) Analysis
  • 03:28Sub-Region of Interest (ROI) Analysis
  • 05:19Results: Impact of Size of ROI on Aβ-Positive Area Quantification in the APP/PS1 Transgenic Mouse of Alzheimer’s Disease
  • 06:50Conclusion

Summary

Automatic Translation

本方案描述并比较了对矢状小鼠脑切片进行全区域或子区域感兴趣分析的程序,以量化阿尔茨海默病的APP / PS1转基因小鼠模型中的淀粉样蛋白-β负荷。

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