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Immunology and Infection

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口服联合抗逆转录病毒治疗HIV-1感染人源化小鼠

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Immunology and Infection

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JoVE Journal Immunology and Infection

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice

Please note that all translations are automatically generated. Click here for the English version.

口服联合抗逆转录病毒治疗HIV-1感染人源化小鼠

DOI:

10.3791/63696-v

•

06:07 min

•

October 06, 2022

•

Wenli Mu, Anjie Zhen, Mayra A. Carrillo, Valerie Rezek, Heather Martin, Miguel Lizarraga, Scott Kitchen

¹Division of Hematology and Oncology, David Geffen School of Medicine,University of California, Los Angeles

Chapters

00:05Introduction
01:07Preparation and Administration of ART Drugs to HIV-1 Infected Mice
03:59Results: A Method for Oral Administration of cART for HIV-1 Infected Humanized Mice
05:38Conclusion

Summary

Automatic Translation

该协议描述了一种提供口服联合抗逆转录病毒药物的新方法，该方法成功抑制人源化小鼠中的HIV-1 RNA复制。

Tags

Oral Antiretroviral Treatment HIV-1 Humanized Mice CART FTC TDF RAL ELV DMSO Trimethoprim Sulfamethoxazole Drug Delivery Preclinical Studies HIV Cure

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