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Establishment and Evaluation of a Porcine Vein Graft Disease Model
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JoVE Journal Medicine
Establishment and Evaluation of a Porcine Vein Graft Disease Model

Establishment and Evaluation of a Porcine Vein Graft Disease Model

DOI:
10.3791/63896-v

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08:50 min

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July 25, 2022

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, , , , , , , , , ,
1Department of Cardiovascular Surgery,the First Affiliated Hospital of Jinan University, 2Guangdong Provincial Key Laboratory of Laboratory Animals,Guangdong Laboratory Animals Monitoring Institute, 3The First Affiliated Hospital of Jinan University

Chapters

  • 00:05Introduction
  • 00:34Preparation of Animals for Surgery
  • 01:29Surgical Procedures
  • 05:09Ultrasonic Examination Venous Graft Tissue Collection
  • 07:18Results: Ultrasonic and Histological Analysis of the Grafts
  • 08:16Conclusion

Summary

Automatic Translation

Automatic Translation

In this protocol, novel pig vein bypass grafting was performed through a small incision in the left chest wall without cardiopulmonary bypass. A postoperative pathology study was done, which showed intimal thickening.

Tags

Keywords: Porcine Vein Graft Disease ModelCoronary Graft DiseaseMinipigsInternal Mammary VeinRight Coronary ArteryIschemia-reperfusionAnimal Model EstablishmentPathological Control

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