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Coronavirus / COVID-19 Procedures
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JoVE Science Education Coronavirus / COVID-19 Procedures
COVID-19 / Coronavirus Outbreak: Protecting The Airway – Endotracheal Intubation

COVID-19 / コロナウイルスの流行: 気道を守る - 気管内挿管

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Overview

パンデミックの時代には、医療スタッフが感染と戦う上で重要なリソースになりつつあります。最高の医療を達成するためには、関連する技術と手順を医療スタッフに教え、感染のリスクを減らす必要があります。COVID患者は、多くの場合、プログレエントな呼吸不全のために機械的換気を必要とするため、気管内挿管は、これらの患者を管理する上で重要な手順になります。この手順は、エアロゾル形成と安全でない気道での作業による感染のリスクが高い.患者の安全を無視してはならないし、低酸素血症や抱負のような合併症は避けるべきである。同時に、大流行の人的資源を守らなければならないため、感染からの個人保護が最も重要である。このビデオは、個人感染保護を考慮に入れながら気管内挿管の手順を示しています。

Procedure

このプロトコルの主な目的は、エアロゾル形成の減少と迅速なシーケンス誘導です。 このプロトコルには、初期挿管のための低い閾値を保持し、最初の行でビデオ喉頭鏡検査を使用し、エアロゾル形成を減らすために高流量酸素療法を避け、部屋にできるだけ少ない人員を持ち、準備と手順のためのチェックリストを使用するなど、いくつかの重要な推奨事項があります。 患者室の外に必要な材料を準備します。 チームに概要を示します。 ドンの個人的な保護具(ガウン、帽子、ゴーグル、手袋)だけでなく、オープン気道で作業するための追加のギア:FFP3 / N-95マスク、バイザー、および手袋の第二のペア。 ダブルフィルターを人工呼吸器に接続し、換気管の接続ポイントを確認します。 保留中の手順について患者に通知し、同意を得る。 行力学モニタリング(ECG、SpO2、NBP)を取得する。 上半身を上げることにより患者の位置と挿管要件を最適化します。 吸引ユニットをテストします。 静脈アクセスをテストします(最小2)。 チーム全体を停止する:10分間の原則(問題、意見、事実、計画について話し合う)とプロセスチェックリストに従ってください。 酸素供給を停止し(O2鼻カニューレを所定の位置に残す)、患者の保護マスクを取り外します。 呼吸マスクを置き、両手で締めます。 O2 鼻カニューレを通して酸素供給を3リットル/分で始めます。 FiO2 1.0(圧力サポートなしCPAP、PEEP 5 mbar)で3〜5分間前酸素化を開始します。 血行力学をチェックし、低血圧のために血管圧器を準備します。 麻酔薬と筋弛緩剤を素早く投与し、少なくとも45秒待ちます。これは、良好な挿管状態を達成し、患者が挿管中に咳をしないようにするために行われます。 鼻カニューレを通して酸素供給を停止し、その後、人工呼吸器を停止します。 呼吸マスクを取り外し、患者の横に安全に置きます。 ビデオ喉頭鏡検査を使用して気管内挿管を行い、保護されていない気道に近づきすぎないようにします。チューブが所定の位置に入ったらすぐに袖口をブロックします。 統合された閉じられた吸引の単位と換気装置を接続する。 人工呼吸器管の接続場所を確認してください。 人工呼吸器を起動します。 カプノグラフィーとオースカルテーションで正しいチューブ配置を確認します。 O2 鼻カニューレを取り外す 気管チューブを固定します。 手袋の外側のペアを取り外します。 胃管を挿入します。 予想外に困難な気道の場合、サモラグ気道装置はエアロゾル形成の危険性が低いためマスク換気よりも好ましい。困難な気道に必要なすべての材料は、汚染された領域の外側に配置する必要があり、追加のアシスタントへの迅速なアクセスを確保する必要があります。

Disclosures

No conflicts of interest declared.

Transcript

Dearest colleagues. The aims of early intubation in COVID-19 patients with respiratory failure are both to prevent aerosolization of respiratory tract fluids and avoid intubation under emergency conditions.

A low threshold for early intubation of COVID-19 patients should be held and a modified rapid sequence induction with videolaryngoscopic intubation utilized. High-flow or non-invasive ventilation therapy should be avoided, and if not possible, used for the shortest period of time.

Fiber optic intubation should also be avoided due to risk of aerosolization. All necessary equipment for intubation is prepared outside of the patient’s room.

The team should be kept to the minimal number of personnel required to carry out the procedure. Typically, this would consist of one intubating doctor, a doctor with oversight who also manages the cardiovascular system, a nurse or operating department assistant to operate the ventilator, and a second nurse or operating department practitioner to apply the anesthetic agents and supply intubation equipment.

Additionally, there should be a runner assigned to wait outside of the room. In case additional equipment or materials are needed, an intubation checklist, which is tailor-made by every hospital according to their resources will now be carried out by the second doctor and will be clearly communicated to the team.

The airway trolley is placed outside of the room so that all potential and necessary airway equipment is quickly available. This includes supraglottic airway devices, such as laryngeal mask airways and esophageal tracheal double-lumen airways. The on-call EMT tracheostomy team should also be contactable and the telephone number known.

The connecting ports of the prepared ventilator are tested. An HME filter is connected between the Y-piece and the respiratory mask. The patient is informed of the anesthesia and intubation procedure in order to attain informed consent.

Complete vital sign monitoring is to be carried out and the ECG tone switched on. The working environment must be optimized. Ensure enough space is around the bed. The pillow is removed, and the patient positioned in a head-up position. The suction system must be fully functional with the suction catheter attached and in reaching distance of the intubating doctor. The patient should have a minimal of two intravenous cannulas, which are tested prior to intubation.

Before beginning the procedure, the team must follow a 10 second for 10 minute principle where facts, procedural planning, potential complications, and team roles are clarified and outstanding questions can be answered. The second doctor also reads and ensures that the recommendations in the airway protection checklist in COVID-19 patients is sufficiently completed. The procedure may begin once everything is clarified.

The oxygen supply to the nasal cannula is turned off. The patient’s protective mask then removed. The respiratory mask is placed and held directly on the patient’s mouth and nose with a C-grip technique. As soon as the mask is airtight, oxygen is provided through the nasal cannula at a flow rate of 3 liters per minute. The ventilator is set to a CPAP mode without pressure support and with a PEEP of 5 and FI02 of 1. The patient should be pre-oxygenated for a total of three to five minutes.

Meanwhile, the patient’s cardiovascular state is monitored, and if required, catecholamine therapy initiated. Now, the five minutes are over. In the context of a rapid sequence induction, all anesthetic agents are rapidly applied. The purpose is to achieve a rapid and deep state of anesthesia without eliciting a cough reflex or hiccup. There will be a 45-second pause after the application of muscle relaxants.

The oxygen supply over the nasal cannula is stopped. However, the nasal cannula is left in place. The ventilator is also paused. The respiratory mask is either hung to the side or placed in a kidney dish next to the patient’s head and held by the assistant positioned near the ventilator. Intubation will now be attempted through videolaryngoscopy and with an endotracheal tube with a pre-positioned bougie within. It is important to maintain as much distance as possible between the intubating doctor and the patient.

After the removal of the bougie, the endotracheal tube cuff must be blocked quickly to prevent aerosolization. The assistant detaches the respiratory mask from the breathing circuit, and places this, in turn, in a kidney dish. A closed suction system is attached to the breathing circuit and once any leaks are eliminated, ventilation can be continued.

The tube position is confirmed through capnography and auscultation. Contamination can be minimized by having a dedicated stethoscope for each patient, which is left by the patient’s bed. Now, the nasal cannula are cut and removed. The endotracheal tube is then fixed. The first pair of gloves are removed and disposed of.

Now, a nasogastric tube should be inserted and its position checked and then fixed. Per the procedures, difficult airway algorithms are well established and are also relevant in COVID-19 patients. The airway or emergency trolley is pre-prepared with all potentially necessary equipment and is placed outside of the patient room.

An allocated runner is made available to pass any equipment on to the intubated team. Supraglottic airways, such as a laryngeal tube should be utilized early on in the algorithm. This is because the potential for leakage or aerosolization of respiratory tract droplets is lower than when compared to bag mask ventilation through a normal respiratory mask. If a second intubation attempt is required, then cricothyroid pressure can be applied. If a further attempt is required, then the second doctor from the team may carry this out.

Early consideration of the need for additional personnel or technical assistance is important as donning of personal protection equipment requires significant time. If a surgical airway is necessary, such as an emergency tracheotomy, then EMT colleagues must be informed early on. Extubation should be carried out by a team of two individuals with full personal protection equipment.

The first person stands next to the ventilator. The second loosens the endotracheal tube fixation tape and operates the closed suction system. The patient is ventilated with an FI02 of 1.0 prior to extubation and with a PEEP of 5. The ventilator is placed on standby immediately prior to extubation. The patient must then be continuously suctioned whilst the endotracheal tube is carefully removed.

The breathing system may not at any point be disconnected. A tight-fitting respiratory mask is placed on the patient covering the mouth and nose, and all vital signs with particular attention to the respiratory function must be monitored.

Thank you.

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JoVE Science Education Database. JoVE Science Education. COVID-19 / Coronavirus Outbreak: Protecting The Airway – Endotracheal Intubation. JoVE, Cambridge, MA, (2020).