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高悪性度漿液性卵巣癌患者由来オルガノイドの作製と培養
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
Generation and Culturing of High-Grade Serous Ovarian Cancer Patient-Derived Organoids
DOI:

07:19 min

January 06, 2023

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Chapters

  • 00:05Introduction
  • 00:51Harvesting Organoids from Tissue
  • 03:58Passaging of Organoids
  • 05:05Freezing and Thawing of Organoids
  • 06:22Results: Generating Patient-Derived Ovarian Cancer Organoids from Patient Tumors, Ascites, and Pleural Fluid Samples
  • 06:42Conclusion

Summary

Automatic Translation

患者由来オルガノイド(PDO)は、 in vitroで腫瘍環境を模倣できる3次元(3D)培養です。高悪性度漿液性卵巣がんにおいて、PDOは新しいバイオマーカーと治療法を研究するためのモデルです。

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