Journal
/
Medicine
/
A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal Medicine
A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

DOI:
10.3791/64914-v

•

05:18 min

•

February 17, 2023

•

, , , , , ,
1College of Nursing,Chengdu University of Traditional Chinese Medicine

Chapters

  • 00:04Introduction
  • 01:04Induction of Type 1 Diabetes Mellitus (T1DM) Model
  • 02:21Construction of the Wound Model
  • 03:18Results: Wound Healing Study in Type I Diabetes Mellitus
  • 04:51Conclusion

Summary

Automatic Translation

Automatic Translation

The streptozotocin-induced diabetic wound model in male SD rats is currently the most widely used model for studying wound healing in type I diabetes mellitus. This protocol describes the methods used to construct this model. It also presents and addresses potential challenges and examines the progression and angiogenic characteristics of diabetic wounds.

Tags

Keywords: Rat Wound ModelType 1 DiabetesStreptozotocinChronic Diabetic WoundsWound HealingAngiogenesisBlood Glucose MeasurementSkin ShavingDepilatory CreamSkin DisinfectionSkin IncisionWound Dressing

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

check_url/64914?article_type=v

A Simplified Technique for Producing an Ischemic Wound Model
check_url/64914?article_type=v

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
check_url/64914?article_type=v

Murine Model of Wound Healing
check_url/64914?article_type=v

A Model of Chronic Nutrient Infusion in the Rat
check_url/64914?article_type=v

A Mouse Fetal Skin Model of Scarless Wound Repair
check_url/64914?article_type=v

Leprdb Mouse Model of Type 2 Diabetes: Pancreatic Islet Isolation and Live-cell 2-Photon Imaging Of Intact Islets
check_url/64914?article_type=v

Demonstration of the Rat Ischemic Skin Wound Model
check_url/64914?article_type=v

Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol
check_url/64914?article_type=v

Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing
check_url/64914?article_type=v

A High-Throughput Electrochemiluminescence 7-Plex Assay Simultaneously Screening for Type 1 Diabetes and Multiple Autoimmune Diseases

Read Article