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A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes
 

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

Article DOI: 10.3791/64914-v 05:18 min February 17th, 2023
February 17th, 2023

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Summary

The streptozotocin-induced diabetic wound model in male SD rats is currently the most widely used model for studying wound healing in type I diabetes mellitus. This protocol describes the methods used to construct this model. It also presents and addresses potential challenges and examines the progression and angiogenic characteristics of diabetic wounds.

Tags

Keywords: Rat Wound Model Type 1 Diabetes Streptozotocin Chronic Diabetic Wounds Wound Healing Angiogenesis Blood Glucose Measurement Skin Shaving Depilatory Cream Skin Disinfection Skin Incision Wound Dressing
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