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使用银纳米颗粒改善小鼠骨关节炎

JoVE Journal
Medicine

This content is Free Access.

JoVE Journal Medicine

Ameliorating Osteoarthritis in Mice Using Silver Nanoparticles

Please note that all translations are automatically generated. Click here for the English version.

使用银纳米颗粒改善小鼠骨关节炎

DOI:

10.3791/65111-v

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05:50 min

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June 02, 2023

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Yuan Sang*¹, Junbin Zhang*¹, Chang Liu, Kaihua Liu, Hui Yao, Huiqing Zhao, Wenbin Xu, Yichun Xu, Gang Hou

¹Department of Orthopedics,The Third Affiliated Hospital of Sun Yat-sen University

Chapters

00:00Introduction
00:44Knee Osteoarthritis (KOA) Mouse Model Establishment
01:41Synthesis of Silver Nanoparticle and Treatment of Collagenase‐Induced KOA Mice
03:10Staining of the Collected Knee Joint and Synovial Tissue
03:55Results: Comparative Analysis of KOA and Silver Nanoparticle‐Treated Murine Groups
05:24Conclusion

Summary

Automatic Translation

这里介绍的是一种利用银纳米颗粒有效改善II型胶原酶诱导的骨关节炎小鼠急性症状的方案，包括滑膜炎症、滑膜增生、血管增生等。

Tags

Keywords: Silver Nanoparticles Osteoarthritis Knee Joint Collagenase Type 1 Collagen Surgical Procedure Animal Experimentation Joint Injection Inflammation

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