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Journal
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Chemistry
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Enrichment of Host Cell Proteins in Monoclonal Antibody Drug Products
/
Author Spotlight: Detecting Low-Abundant Host Cell Proteins in Drug Products Using Enrichment Beads and Limited Digestion
JoVE Journal
Chemistry
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JoVE Journal
Chemistry
Host Cell Protein Analysis using Enrichment Beads Coupled with Limited Digestion
Author Spotlight: Detecting Low-Abundant Host Cell Proteins in Drug Products Using Enrichment Beads and Limited Digestion
Enrichment of Host Cell Proteins in Monoclonal Antibody Drug Products
DOI:
10.3791/65544-v
•
02:35 min
•
January 19, 2024
•
Sisi Zhang
,
Hui Xiao
,
Ning Li
1
Analytical Chemistry
,
Regeneron Pharmaceuticals Inc.
Tags
Host Cell Protein
HCP Analysis
Proteome Enrichment Beads
Limited Digestion
Dynamic Range
ProteoMiner Technology
Nano LC-MS/MS
Monoclonal Antibody
Therapeutic Proteins
Impurities
Risk Assessment
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Author Spotlight: Detecting Low-Abundant Host Cell Proteins in Drug Products Using Enrichment Beads and Limited Digestion
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