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Journal
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Biochemistry
/
Accelerating Macromolecular Structural Analysis Using Smart Leginon Autoscreen
/
Author Spotlight: Enhancing Cryo-Electron Microscopy by Automated Data Collection and Analysis Techniques
JoVE Journal
Biochemistry
This content is Free Access.
JoVE Journal
Biochemistry
Cryo-Electron Microscopy Screening Automation Across Multiple Grids Using Smart Leginon
Author Spotlight: Enhancing Cryo-Electron Microscopy by Automated Data Collection and Analysis Techniques
Accelerating Macromolecular Structural Analysis Using Smart Leginon Autoscreen
DOI:
10.3791/66007-v
•
01:41 min
•
December 01, 2023
•
Anjelique Sawh-Gopal
2
,
Aygul Ishemgulova*
1
,
Eugene Y. D. Chua*
1
,
Mahira F. Aragon*
1
,
Joshua H. Mendez
,
Edward T. Eng
,
Alex J. Noble
1
Simons Electron Microscopy Center, New York Structural Biology Center
,
2
Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology
Tags
Keywords: Cryo-electron Microscopy
Screening Automation
Smart Leginon
Data Collection
Data Analysis
Machine Learning
Particle Picking
3D Flexibility Analysis
Model Building
Grid Screening
Sample Preparation
CryoEM Workflow
Structural Biology
Macromolecular Protein Complexes
Grid Optimization
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Author Spotlight: Enhancing Cryo-Electron Microscopy by Automated Data Collection and Analysis Techniques
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Using Smart Leginon Autoscreen for CryoEM Grid Screening
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