Alexey Kostikov McConnell Brain Imaging Centre, Montreal Neurological Institute McGill University Biography Publications Institution JoVE Articles Alexey Kostikov has not added a biography. If you are Alexey Kostikov and would like to personalize this page please email our Author Liaison for assistance. Publications Radiosynthesis of the Diastereomerically Pure (E)-[ C]ABP688 Journal of Labelled Compounds & Radiopharmaceuticals. Aug, 2019 | Pubmed ID: 31418468 Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging Pharmaceuticals (Basel, Switzerland). Jan, 2019 | Pubmed ID: 30609832 Effect of (Z)-isomer Content on [C]ABP688 Binding Potential in Humans European Journal of Nuclear Medicine and Molecular Imaging. May, 2019 | Pubmed ID: 30607444 A Simplified Radiosynthesis of [ F]MK-6240 for Tau PET Imaging Journal of Labelled Compounds & Radiopharmaceuticals. 02, 2019 | Pubmed ID: 30426529 Identification of [F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging Journal of Medicinal Chemistry. 02, 2018 | Pubmed ID: 29257860 [F]ODIBO: a Prosthetic Group for Bioorthogonal Radiolabeling of Macromolecules Via Strain-promoted Alkyne-azide Cycloaddition Organic & Biomolecular Chemistry. 01, 2018 | Pubmed ID: 29170778 Multimodal Imaging in Rat Model Recapitulates Alzheimer's Disease Biomarkers Abnormalities The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 12, 2017 | Pubmed ID: 29097597 Highly Efficient Solid Phase Supported Radiosynthesis of [ C]PiB Using TC18 Cartridge As a "3-in-1" Production Entity Journal of Labelled Compounds & Radiopharmaceuticals. 12, 2017 | Pubmed ID: 28981146 A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human Journal of Medicinal Chemistry. 08, 2017 | Pubmed ID: 28696690 Development of "[C]kits" for a Fast, Efficient and Reliable Production of Carbon-11 Labeled Radiopharmaceuticals for Positron Emission Tomography Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine. Mar, 2017 | Pubmed ID: 28038410 Towards the PET Radiotracer for P75 Neurotrophin Receptor: [(11)C]LM11A-24 Shows Biological Activity in Vitro, but Unfavorable Ex Vivo and in Vivo Profile Bioorganic & Medicinal Chemistry. 10, 2016 | Pubmed ID: 27567078 Which Aspects of Stroke Do Animal Models Capture? A Multitracer Micro-PET Study of Focal Ischemia with Endothelin-1 Cerebrovascular Diseases (Basel, Switzerland). 2016 | Pubmed ID: 26752046 In Vivo Characterization of Metabotropic Glutamate Receptor Type 5 Abnormalities in Behavioral Variant FTD Brain Structure & Function. Apr, 2016 | Pubmed ID: 25596865 In Vivo Evaluation of ¹⁸F-SiFAlin-Modified TATE: A Potential Challenge for ⁶⁸Ga-DOTATATE, the Clinical Gold Standard for Somatostatin Receptor Imaging with PET Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jul, 2015 | Pubmed ID: 25977461 Syntheses and Evaluation of Carbon-11- and Fluorine-18-radiolabeled Pan-tropomyosin Receptor Kinase (Trk) Inhibitors: Exploration of the 4-aza-2-oxindole Scaffold As Trk PET Imaging Agents ACS Chemical Neuroscience. Feb, 2015 | Pubmed ID: 25350780 ¹⁸F-labeled Silicon-based Fluoride Acceptors: Potential Opportunities for Novel Positron Emitting Radiopharmaceuticals BioMed Research International. 2014 | Pubmed ID: 25157357 Cholinergic Depletion in Alzheimer's Disease Shown by [ (18) F]FEOBV Autoradiography International Journal of Molecular Imaging. 2013 | Pubmed ID: 24324884 Concordance Between in Vivo and Postmortem Measurements of Cholinergic Denervation in Rats Using PET with [18F]FEOBV and Choline Acetyltransferase Immunochemistry EJNMMI Research. Oct, 2013 | Pubmed ID: 24103360 GABAA Receptors Predict Aversion-related Brain Responses: an FMRI-PET Investigation in Healthy Humans Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Jul, 2013 | Pubmed ID: 23389691 Synthesis of [(18)F]SiFB: a Prosthetic Group for Direct Protein Radiolabeling for Application in Positron Emission Tomography Nature Protocols. Nov, 2012 | Pubmed ID: 23037310 Oxalic Acid Supported Si-18F-radiofluorination: One-step Radiosynthesis of N-succinimidyl 3-(di-tert-butyl[18F]fluorosilyl)benzoate ([18F]SiFB) for Protein Labeling Bioconjugate Chemistry. Jan, 2012 | Pubmed ID: 22148255 T-Bu2SiF-derivatized D2-receptor Ligands: the First SiFA-containing Small Molecule Radiotracers for Target-specific PET-imaging Molecules (Basel, Switzerland). Sep, 2011 | Pubmed ID: 21892125 Where In-vivo Imaging Meets Cytoarchitectonics: the Relationship Between Cortical Thickness and Neuronal Density Measured with High-resolution [18F]flumazenil-PET NeuroImage. Jun, 2011 | Pubmed ID: 21073964 Pet İzleyicilerin Üretimi için Katı Faz 11C-Metilasyon, Arıtma ve Formülasyon Thomas A. Singleton*1, Mehdi Boudjemeline*1, Robert Hopewell1, Dean Jolly1, Hussein Bdair1, Alexey Kostikov1,2 1McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, 2Department of Neurology and Neurosurgery, McGill University JoVE 60237 Chemistry
Pet İzleyicilerin Üretimi için Katı Faz 11C-Metilasyon, Arıtma ve Formülasyon Thomas A. Singleton*1, Mehdi Boudjemeline*1, Robert Hopewell1, Dean Jolly1, Hussein Bdair1, Alexey Kostikov1,2 1McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, 2Department of Neurology and Neurosurgery, McGill University JoVE 60237 Chemistry