Bon-Kyoung Koo Wellcome Trust - Medical Research Council Stem Cell Institute University of Cambridge Biography Publications Institution JoVE Articles Bon-Kyoung Koo has not added a biography. If you are Bon-Kyoung Koo and would like to personalize this page please email our Author Liaison for assistance. Publications Stem Cells in Repair of Gastrointestinal Epithelia Physiology (Bethesda, Md.). Jul, 2017 | Pubmed ID: 28615312 Long-term, Hormone-responsive Organoid Cultures of Human Endometrium in a Chemically Defined Medium Nature Cell Biology. May, 2017 | Pubmed ID: 28394884 One-step Generation of Conditional and Reversible Gene Knockouts Nature Methods. Mar, 2017 | Pubmed ID: 28135257 Adult Gastric Stem Cells and Their Niches Wiley Interdisciplinary Reviews. Developmental Biology. Mar, 2017 | Pubmed ID: 28044412 Simultaneous Paralogue Knockout Using a CRISPR-concatemer in Mouse Small Intestinal Organoids Developmental Biology. Dec, 2016 | Pubmed ID: 27983963 Organoids: A New in Vitro Model System for Biomedical Science and Disease Modelling and Promising Source for Cell-based Transplantation Developmental Biology. Dec, 2016 | Pubmed ID: 27983962 Clonal Evolution of Stem Cells in the Gastrointestinal Tract Advances in Experimental Medicine and Biology. 2016 | Pubmed ID: 27573765 Culture and Establishment of Self-renewing Human and Mouse Adult Liver and Pancreas 3D Organoids and Their Genetic Manipulation Nature Protocols. Sep, 2016 | Pubmed ID: 27560176 Adult Stem Cell Lineage Tracing and Deep Tissue Imaging BMB Reports. Dec, 2015 | Pubmed ID: 26634741 Modeling Mouse and Human Development Using Organoid Cultures Development (Cambridge, England). Sep, 2015 | Pubmed ID: 26395140 Porcupine Inhibitor Suppresses Paracrine Wnt-driven Growth of Rnf43;Znrf3-mutant Neoplasia Proceedings of the National Academy of Sciences of the United States of America. Jun, 2015 | Pubmed ID: 26023187 Ascl2 Acts As an R-spondin/Wnt-responsive Switch to Control Stemness in Intestinal Crypts Cell Stem Cell. Feb, 2015 | Pubmed ID: 25620640 Stem Cells Marked by the R-Spondin Receptor LGR5 Gastroenterology. Aug, 2014 | Pubmed ID: 24859206 Retroviral Gene Expression Control in Primary Organoid Cultures Current Protocols in Stem Cell Biology. 2013 | Pubmed ID: 24510288 Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients Cell Stem Cell. Dec, 2013 | Pubmed ID: 24315439 Generation of BAC Transgenic Epithelial Organoids PloS One. 2013 | Pubmed ID: 24204693 Differentiated Troy+ Chief Cells Act As Reserve Stem Cells to Generate All Lineages of the Stomach Epithelium Cell. Oct, 2013 | Pubmed ID: 24120136 ER Stress Causes Rapid Loss of Intestinal Epithelial Stemness Through Activation of the Unfolded Protein Response Cell Reports. Apr, 2013 | Pubmed ID: 23545496 Tumour Suppressor RNF43 is a Stem-cell E3 Ligase That Induces Endocytosis of Wnt Receptors Nature. Aug, 2012 | Pubmed ID: 22895187 Notch1 Counteracts WNT/β-catenin Signaling Through Chromatin Modification in Colorectal Cancer The Journal of Clinical Investigation. Sep, 2012 | Pubmed ID: 22863622 The Lgr5 Intestinal Stem Cell Signature: Robust Expression of Proposed Quiescent '+4' Cell Markers The EMBO Journal. Jul, 2012 | Pubmed ID: 22692129 A Critical Role for the Wnt Effector Tcf4 in Adult Intestinal Homeostatic Self-renewal Molecular and Cellular Biology. May, 2012 | Pubmed ID: 22393260 Controlled Gene Expression in Primary Lgr5 Organoid Cultures Nature Methods. Jan, 2012 | Pubmed ID: 22138822 Survival and Differentiation of Mammary Epithelial Cells in Mammary Gland Development Require Nuclear Retention of Id2 Due to RANK Signaling Molecular and Cellular Biology. Dec, 2011 | Pubmed ID: 21947283 Lgr5 Homologues Associate with Wnt Receptors and Mediate R-spondin Signalling Nature. Aug, 2011 | Pubmed ID: 21727895 The WNT Antagonist Dickkopf2 Promotes Angiogenesis in Rodent and Human Endothelial Cells The Journal of Clinical Investigation. May, 2011 | Pubmed ID: 21540552 Inactivation of Notch Signaling in the Renal Collecting Duct Causes Nephrogenic Diabetes Insipidus in Mice The Journal of Clinical Investigation. Nov, 2009 | Pubmed ID: 19855135 Essential Role of CR6-interacting Factor 1 (Crif1) in E74-like Factor 3 (ELF3)-mediated Intestinal Development The Journal of Biological Chemistry. Nov, 2009 | Pubmed ID: 19801644 Notch Signaling Promotes the Generation of EphrinB1-positive Intestinal Epithelial Cells Gastroenterology. Jul, 2009 | Pubmed ID: 19332065 Mind Bomb 1 in the Lymphopoietic Niches is Essential for T and Marginal Zone B Cell Development The Journal of Experimental Medicine. Oct, 2008 | Pubmed ID: 18824586 Defective Notch Activation in Microenvironment Leads to Myeloproliferative Disease Blood. Dec, 2008 | Pubmed ID: 18818392 Mind Bomb-1 is Essential for Intraembryonic Hematopoiesis in the Aortic Endothelium and the Subaortic Patches Molecular and Cellular Biology. Aug, 2008 | Pubmed ID: 18505817 Mind Bomb 1-expressing Intermediate Progenitors Generate Notch Signaling to Maintain Radial Glial Cells Neuron. May, 2008 | Pubmed ID: 18498734 A Crucial Role of WW45 in Developing Epithelial Tissues in the Mouse The EMBO Journal. Apr, 2008 | Pubmed ID: 18369314 Crif1 is a Novel Transcriptional Coactivator of STAT3 The EMBO Journal. Feb, 2008 | Pubmed ID: 18200042 An Obligatory Role of Mind Bomb-1 in Notch Signaling of Mammalian Development PloS One. 2007 | Pubmed ID: 18043734 Neuralized-2 Regulates a Notch Ligand in Cooperation with Mind Bomb-1 The Journal of Biological Chemistry. Nov, 2006 | Pubmed ID: 17003037 Snx5, As a Mind Bomb-binding Protein, is Expressed in Hematopoietic and Endothelial Precursor Cells in Zebrafish FEBS Letters. Aug, 2006 | Pubmed ID: 16857196 Receptor Activator of NF-kappaB Ligand Regulates the Proliferation of Mammary Epithelial Cells Via Id2 Molecular and Cellular Biology. Feb, 2006 | Pubmed ID: 16428453 Mind Bomb 1 is Essential for Generating Functional Notch Ligands to Activate Notch Development (Cambridge, England). Aug, 2005 | Pubmed ID: 16000382 Mind Bomb-2 is an E3 Ligase for Notch Ligand The Journal of Biological Chemistry. Jun, 2005 | Pubmed ID: 15824097 פרוטוקול של נוקאוט גנים מרובים עכבר קטן Organoids באמצעות CISPR-concatemer Alessandra Merenda1,2, Amanda Andersson-Rolf1,2, Roxana C. Mustata1, Taibo Li1, Hyunki Kim3, Bon-Kyoung Koo1,2 1Wellcome Trust - Medical Research Council Stem Cell Institute, University of Cambridge, 2Department of Genetics, University of Cambridge, 3Department of Pathology, Yonsei University College of Medicine JoVE 55916 Bioengineering פרוטוקול וידאו של זיהום retroviral ביסודי מעיים Organoid תרבות Amanda Andersson-Rolf1,2, Juergen Fink1,2, Roxana C. Mustata2, Bon-Kyoung Koo1,2 1Department of Genetics, University of Cambridge, 2Wellcome Trust - Medical Research Council Stem Cell Institute, University of Cambridge JoVE 51765 Biology
פרוטוקול של נוקאוט גנים מרובים עכבר קטן Organoids באמצעות CISPR-concatemer Alessandra Merenda1,2, Amanda Andersson-Rolf1,2, Roxana C. Mustata1, Taibo Li1, Hyunki Kim3, Bon-Kyoung Koo1,2 1Wellcome Trust - Medical Research Council Stem Cell Institute, University of Cambridge, 2Department of Genetics, University of Cambridge, 3Department of Pathology, Yonsei University College of Medicine JoVE 55916 Bioengineering
פרוטוקול וידאו של זיהום retroviral ביסודי מעיים Organoid תרבות Amanda Andersson-Rolf1,2, Juergen Fink1,2, Roxana C. Mustata2, Bon-Kyoung Koo1,2 1Department of Genetics, University of Cambridge, 2Wellcome Trust - Medical Research Council Stem Cell Institute, University of Cambridge JoVE 51765 Biology