Carlie A. LaLone Office of Research and Development, Center for Computational Toxicology and Exposure, Great Lakes Toxicology and Ecology Division U.S. Environmental Protection Agency Biography Publications Institution JoVE Articles Carlie A. LaLone has not added a biography. If you are Carlie A. LaLone and would like to personalize this page please email our Author Liaison for assistance. Publications Current Ecotoxicity Testing Needs Among Selected U.S. Federal Agencies Regulatory Toxicology and Pharmacology : RTP. Aug, 2022 | Pubmed ID: 35660046 Assessing Effects of Aromatase Inhibition on Fishes with Group-synchronous Oocyte Development Using Western Mosquitofish (Gambusia Affinis) As a Model Aquatic Toxicology (Amsterdam, Netherlands). Jan, 2021 | Pubmed ID: 33450672 Nontarget Screening of Per- and Polyfluoroalkyl Substances Binding to Human Liver Fatty Acid Binding Protein Environmental Science & Technology. May, 2020 | Pubmed ID: 32249562 Quantitative Response-Response Relationships Linking Aromatase Inhibition to Decreased Fecundity Are Conserved Across Three Fishes with Asynchronous Oocyte Development Environmental Science & Technology. Sep, 2019 | Pubmed ID: 31386814 Differential Sensitivity to In Vitro Inhibition of Cytochrome P450 Aromatase (CYP19) Activity Among 18 Freshwater Fishes Toxicological Sciences : an Official Journal of the Society of Toxicology. Aug, 2019 | Pubmed ID: 31099392 In Silico Site-Directed Mutagenesis Informs Species-Specific Predictions of Chemical Susceptibility Derived From the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) Tool Toxicological Sciences : an Official Journal of the Society of Toxicology. Nov, 2018 | Pubmed ID: 30060110 Derivation and Evaluation of Putative Adverse Outcome Pathways for the Effects of Cyclooxygenase Inhibitors on Reproductive Processes in Female Fish Toxicological Sciences : an Official Journal of the Society of Toxicology. Apr, 2017 | Pubmed ID: 28201806 Weight of Evidence Evaluation of a Network of Adverse Outcome Pathways Linking Activation of the Nicotinic Acetylcholine Receptor in Honey Bees to Colony Death The Science of the Total Environment. Apr, 2017 | Pubmed ID: 28126277 Editor's Highlight: Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS): A Web-Based Tool for Addressing the Challenges of Cross-Species Extrapolation of Chemical Toxicity Toxicological Sciences : an Official Journal of the Society of Toxicology. Oct, 2016 | Pubmed ID: 27370413 Leveraging Existing Data for Prioritization of the Ecological Risks of Human and Veterinary Pharmaceuticals to Aquatic Organisms Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Nov, 2014 | Pubmed ID: 25405975 Molecular Target Sequence Similarity As a Basis for Species Extrapolation to Assess the Ecological Risk of Chemicals with Known Modes of Action Aquatic Toxicology (Amsterdam, Netherlands). Nov, 2013 | Pubmed ID: 24177217 Current Perspectives on the Use of Alternative Species in Human Health and Ecological Hazard Assessments Environmental Health Perspectives. Jun, 2013 | Pubmed ID: 23771518 Effects of a Glucocorticoid Receptor Agonist, Dexamethasone, on Fathead Minnow Reproduction, Growth, and Development Environmental Toxicology and Chemistry. Mar, 2012 | Pubmed ID: 22189798 Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation Sara M. F. Vliet1, Monique Hazemi2, Donovan Blatz2, Marissa Jensen3, Sally Mayasich4, Thomas R. Transue5, Cody Simmons5, Audrey Wilkinson5, Carlie A. LaLone6 1Office of Research and Development, Center for Computational Toxicology and Exposure, Scientific Computing and Data Curation Division, U.S. Environmental Protection Agency, 2Oak Ridge Institute for Science and Education, 3Swenson College of Science and Engineering, Department of Biology, University of Minnesota Duluth, 4University of Wisconsin-Madison Aquatic Sciences Center, 5General Dynamics Information Technology, Research Triangle Park, 6Office of Research and Development, Center for Computational Toxicology and Exposure, Great Lakes Toxicology and Ecology Division, U.S. Environmental Protection Agency JoVE 63970 Genetics
Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation Sara M. F. Vliet1, Monique Hazemi2, Donovan Blatz2, Marissa Jensen3, Sally Mayasich4, Thomas R. Transue5, Cody Simmons5, Audrey Wilkinson5, Carlie A. LaLone6 1Office of Research and Development, Center for Computational Toxicology and Exposure, Scientific Computing and Data Curation Division, U.S. Environmental Protection Agency, 2Oak Ridge Institute for Science and Education, 3Swenson College of Science and Engineering, Department of Biology, University of Minnesota Duluth, 4University of Wisconsin-Madison Aquatic Sciences Center, 5General Dynamics Information Technology, Research Triangle Park, 6Office of Research and Development, Center for Computational Toxicology and Exposure, Great Lakes Toxicology and Ecology Division, U.S. Environmental Protection Agency JoVE 63970 Genetics