Catherine Bowes Rickman Department of Ophthalmology Duke University Biography Publications Institution JoVE Articles Catherine Bowes Rickman has not added a biography. If you are Catherine Bowes Rickman and would like to personalize this page please email our Author Liaison for assistance. Publications Distinct Phenotypic Consequences of Pathogenic Mutants Associated with Late-Onset Retinal Degeneration The American Journal of Pathology. Oct, 2022 | Pubmed ID: 36328299 Cell Culture Models to Study Retinal Pigment Epithelium-related Pathogenesis in Age-related Macular Degeneration Experimental Eye Research. Sep, 2022 | Pubmed ID: 35835183 Encapsulating Cas9 into Extracellular Vesicles by Protein Myristoylation Journal of Extracellular Vesicles. Apr, 2022 | Pubmed ID: 35384352 Targeting Lipid Metabolism for the Treatment of Age-Related Macular Degeneration: Insights from Preclinical Mouse Models Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics. Month, 2022 | Pubmed ID: 34788573 High-density Lipoproteins Are a Potential Therapeutic Target for Age-related Macular Degeneration The Journal of Biological Chemistry. Sep, 2020 | Pubmed ID: 32737203 Correction To: Retinal Degenerative Diseases Advances in Experimental Medicine and Biology. Month, 2019 | Pubmed ID: 32274704 Isolation of Retinal Exosome Biomarkers from Blood By Targeted Immunocapture Advances in Experimental Medicine and Biology. Month, 2019 | Pubmed ID: 31884583 Four-Dimensional Microscope-Integrated Optical Coherence Tomography Guidance in a Model Eye Subretinal Surgery Retina (Philadelphia, Pa.). Oct, 2019 | Pubmed ID: 31090685 Microglial Function Is Distinct in Different Anatomical Locations During Retinal Homeostasis and Degeneration Immunity. Mar, 2019 | Pubmed ID: 30850344 Human Complement Factor H Y402H Polymorphism Causes an Age-related Macular Degeneration Phenotype and Lipoprotein Dysregulation in Mice Proceedings of the National Academy of Sciences of the United States of America. Feb, 2019 | Pubmed ID: 30808757 Author Correction: Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Scientific Reports. Nov, 2018 | Pubmed ID: 30455433 Polarized Exosome Release from the Retinal Pigmented Epithelium Advances in Experimental Medicine and Biology. Month, 2018 | Pubmed ID: 29721985 Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration Investigative Ophthalmology & Visual Science. Feb, 2018 | Pubmed ID: 29392311 Complement Factor H in AMD: Bridging Genetic Associations and Pathobiology Progress in Retinal and Eye Research. Jan, 2018 | Pubmed ID: 28928087 Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Scientific Reports. Jul, 2017 | Pubmed ID: 28687758 Roles of Exosomes in the Normal and Diseased Eye Progress in Retinal and Eye Research. Jul, 2017 | Pubmed ID: 28465248 Oxidative Stress-mediated NFκB Phosphorylation Upregulates P62/SQSTM1 and Promotes Retinal Pigmented Epithelial Cell Survival Through Increased Autophagy PloS One. Month, 2017 | Pubmed ID: 28222108 Lack of the P2X Receptor Protects Against AMD-like Defects and Microparticle Accumulation in a Chronic Oxidative Stress-induced Mouse Model of AMD Biochemical and Biophysical Research Communications. Jan, 2017 | Pubmed ID: 27810364 AMD and the Alternative Complement Pathway: Genetics and Functional Implications Human Genomics. Jun, 2016 | Pubmed ID: 27329102 A Non-Canonical Role for β-Secretase in the Retina Advances in Experimental Medicine and Biology. Month, 2016 | Pubmed ID: 26427429 Regulation of Age-related Macular Degeneration-like Pathology by Complement Factor H Proceedings of the National Academy of Sciences of the United States of America. Jun, 2015 | Pubmed ID: 25991857 Expression of Human Complement Factor H Prevents Age-related Macular Degeneration-like Retina Damage and Kidney Abnormalities in Aged Cfh Knockout Mice The American Journal of Pathology. Jan, 2015 | Pubmed ID: 25447048 Dysregulated Autophagy in the RPE is Associated with Increased Susceptibility to Oxidative Stress and AMD Autophagy. Month, 2014 | Pubmed ID: 25484094 The Role of Complement Dysregulation in AMD Mouse Models Advances in Experimental Medicine and Biology. Month, 2014 | Pubmed ID: 24664701 Dry Age-related Macular Degeneration: Mechanisms, Therapeutic Targets, and Imaging Investigative Ophthalmology & Visual Science. Dec, 2013 | Pubmed ID: 24335072 β-Secretase (BACE1) Inhibition Causes Retinal Pathology by Vascular Dysregulation and Accumulation of Age Pigment EMBO Molecular Medicine. Sep, 2012 | Pubmed ID: 22903875 Automatic Segmentation of Closed-contour Features in Ophthalmic Images Using Graph Theory and Dynamic Programming Biomedical Optics Express. May, 2012 | Pubmed ID: 22567602 ApoER2 Function in the Establishment and Maintenance of Retinal Synaptic Connectivity The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2011 | Pubmed ID: 21976526 Anti-amyloid Therapy Protects Against Retinal Pigmented Epithelium Damage and Vision Loss in a Model of Age-related Macular Degeneration Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21690377 Serial Analysis of Gene Expression (SAGE) in Normal Human Trabecular Meshwork Molecular Vision. Apr, 2011 | Pubmed ID: 21528004 Heparan Sulfate, Including That in Bruch's Membrane, Inhibits the Complement Alternative Pathway: Implications for Age-related Macular Degeneration Journal of Immunology (Baltimore, Md. : 1950). Nov, 2010 | Pubmed ID: 20876352 The Pivotal Role of the Complement System in Aging and Age-related Macular Degeneration: Hypothesis Re-visited Progress in Retinal and Eye Research. Mar, 2010 | Pubmed ID: 19961953 Developing SDOCT to Assess Donor Human Eyes Prior to Tissue Sectioning for Research Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. Aug, 2009 | Pubmed ID: 19225801 Evaluation of the X-linked High-grade Myopia Locus (MYP1) with Cone Dysfunction and Color Vision Deficiencies Investigative Ophthalmology & Visual Science. Apr, 2009 | Pubmed ID: 19098318 Rapid and Sensitive Method for Detection of Y402, H402, I62, and V62 Variants of Complement Factor H in Human Plasma Samples Using Mass Spectrometry Investigative Ophthalmology & Visual Science. Apr, 2009 | Pubmed ID: 19029036 NEIBank: Genomics and Bioinformatics Resources for Vision Research Molecular Vision. Jul, 2008 | Pubmed ID: 18648525 Recurrent Choroidal Neovascularization After Macular Translocation Surgery with 360-degree Peripheral Retinectomy Retina (Philadelphia, Pa.). Oct, 2008 | Pubmed ID: 18626416 ERG Responses and Microarray Analysis of Gene Expression in a Multifactorial Murine Model of Age-related Retinal Degeneration Advances in Experimental Medicine and Biology. Month, 2008 | Pubmed ID: 18188941 Targeting Age-related Macular Degeneration with Alzheimer's Disease Based Immunotherapies: Anti-amyloid-beta Antibody Attenuates Pathologies in an Age-related Macular Degeneration Mouse Model Vision Research. Feb, 2008 | Pubmed ID: 17888483 Oxidative Stress-induced Expression and Modulation of Phosphatase of Regenerating Liver-1 (PRL-1) in Mammalian Retina Biochimica Et Biophysica Acta. Sep, 2007 | Pubmed ID: 17673310 Initial Observations of Key Features of Age-related Macular Degeneration in APOE Targeted Replacement Mice Advances in Experimental Medicine and Biology. Month, 2006 | Pubmed ID: 17249563 Why Do Mutations in the Ubiquitously Expressed Housekeeping Gene IMPDH1 Cause Retina-specific Photoreceptor Degeneration? Investigative Ophthalmology & Visual Science. Sep, 2006 | Pubmed ID: 16936083 Defining the Human Macula Transcriptome and Candidate Retinal Disease Genes Using EyeSAGE Investigative Ophthalmology & Visual Science. Jun, 2006 | Pubmed ID: 16723438 Recurrence of Retinal Pigment Epithelial Changes After Macular Translocation with 360 Degrees Peripheral Retinectomy for Geographic Atrophy Archives of Ophthalmology (Chicago, Ill. : 1960). Jul, 2005 | Pubmed ID: 16009834 Human RPE Expression of Cell Survival Factors Investigative Ophthalmology & Visual Science. May, 2005 | Pubmed ID: 15851579 Unraveling a Multifactorial Late-onset Disease: from Genetic Susceptibility to Disease Mechanisms for Age-related Macular Degeneration Annual Review of Genomics and Human Genetics. Month, | Pubmed ID: 19405847 Protocole d’évaluation et de quantification des pathologies de l’épithélium pigmenté rétinien dans des modèles murins de dégénérescence maculaire liée à l’âge Michael Landowski1,2, Samuel Grindel1, Ying Hao3, Sakae Ikeda1,2, Catherine Bowes Rickman3,4, Akihiro Ikeda1,2 1Department of Medical Genetics, University of Wisconsin-Madison, 2McPherson Eye Research Institute, University of Wisconsin-Madison, 3Department of Ophthalmology, Duke University, 4Department of Cell Biology, Duke University JoVE 64927 Genetics
Protocole d’évaluation et de quantification des pathologies de l’épithélium pigmenté rétinien dans des modèles murins de dégénérescence maculaire liée à l’âge Michael Landowski1,2, Samuel Grindel1, Ying Hao3, Sakae Ikeda1,2, Catherine Bowes Rickman3,4, Akihiro Ikeda1,2 1Department of Medical Genetics, University of Wisconsin-Madison, 2McPherson Eye Research Institute, University of Wisconsin-Madison, 3Department of Ophthalmology, Duke University, 4Department of Cell Biology, Duke University JoVE 64927 Genetics
