Constantin Radu

Publications

• Evaluation of Compound Optical Interference in High-Content Screening
  SLAS Discovery. Apr, 2017  |   Pubmed ID: 28467117
• High-Content Screening of Raw Actinomycete Extracts for the Identification of Antituberculosis Activities
  SLAS Discovery. Feb, 2017  |   Pubmed ID: 27810952
• Proteasome Addiction Defined in Ewing Sarcoma Is Effectively Targeted by a Novel Class of 19S Proteasome Inhibitors
  Cancer Research. Aug, 2016  |   Pubmed ID: 27256563
• Small-molecule Inhibitors of SETD8 with Cellular Activity
  ACS Chemical Biology. Nov, 2014  |   Pubmed ID: 25137013
• A 1536-well Fluorescence Polarization Assay to Screen for Modulators of the MUSASHI Family of RNA-binding Proteins
  Combinatorial Chemistry & High Throughput Screening. 2014  |   Pubmed ID: 24912481
• Chemical & RNAi Screening at MSKCC: a Collaborative Platform to Discover & Repurpose Drugs to Fight Disease
  Combinatorial Chemistry & High Throughput Screening. May, 2014  |   Pubmed ID: 24661215
• Inhibition of Dengue Virus Replication by a Class of Small-molecule Compounds That Antagonize Dopamine Receptor D4 and Downstream Mitogen-activated Protein Kinase Signaling
  Journal of Virology. May, 2014  |   Pubmed ID: 24599995
• A High-content Assay Strategy for the Identification and Profiling of ABCG2 Modulators in Live Cells
  Assay and Drug Development Technologies. Jan-Feb, 2014  |   Pubmed ID: 23992118
• Flaviviruses Are Sensitive to Inhibition of Thymidine Synthesis Pathways
  Journal of Virology. Sep, 2013  |   Pubmed ID: 23824813
• A Novel High Throughput 1536-well Notch1 γ -secretase AlphaLISA Assay
  Combinatorial Chemistry & High Throughput Screening. Jul, 2013  |   Pubmed ID: 23448293
• An Arrayed Genome-scale Lentiviral-enabled Short Hairpin RNA Screen Identifies Lethal and Rescuer Gene Candidates
  Assay and Drug Development Technologies. Apr, 2013  |   Pubmed ID: 23198867
• An Arrayed RNA Interference Genome-wide Screen Identifies Candidate Genes Involved in the MicroRNA 21 Biogenesis Pathway
  Assay and Drug Development Technologies. Apr, 2013  |   Pubmed ID: 23153064
• Large-scale Screening Using Familial Dysautonomia Induced Pluripotent Stem Cells Identifies Compounds That Rescue IKBKAP Expression
  Nature Biotechnology. Dec, 2012  |   Pubmed ID: 23159879
• Designs and Concept Reliance of a Fully Automated High-content Screening Platform
  Journal of Laboratory Automation. Oct, 2012  |   Pubmed ID: 22797489
• An Image-based Biosensor Assay Strategy to Screen for Modulators of the MicroRNA 21 Biogenesis Pathway
  Combinatorial Chemistry & High Throughput Screening. Aug, 2012  |   Pubmed ID: 22540737
• A High Throughput Scintillation Proximity Imaging Assay for Protein Methyltransferases
  Combinatorial Chemistry & High Throughput Screening. Jun, 2012  |   Pubmed ID: 22256970
• Comparison of Luminescence ADP Production Assay and Radiometric Scintillation Proximity Assay for Cdc7 Kinase
  Combinatorial Chemistry & High Throughput Screening. Sep, 2011  |   Pubmed ID: 21564015
• High-content Assay to Identify Inhibitors of Dengue Virus Infection
  Assay and Drug Development Technologies. Oct, 2010  |   Pubmed ID: 20973722
• Live-cell Imaging of Caspase Activation for High-content Screening
  Journal of Biomolecular Screening. Sep, 2009  |   Pubmed ID: 19726787
• A Miniaturized 1536-well Format Gamma-secretase Assay
  Assay and Drug Development Technologies. Oct, 2009  |   Pubmed ID: 19715456
• Development and Validation of a High-density Fluorescence Polarization-based Assay for the Trypanosoma RNA Triphosphatase TbCet1
  Combinatorial Chemistry & High Throughput Screening. Mar, 2009  |   Pubmed ID: 19275531
• Revisiting Old Drugs As Novel Agents for Retinoblastoma: in Vitro and in Vivo Antitumor Activity of Cardenolides
  Investigative Ophthalmology & Visual Science. Jul, 2009  |   Pubmed ID: 19151399
• A High Density Assay Format for the Detection of Novel Cytotoxic Agents in Large Chemical Libraries
  Journal of Enzyme Inhibition and Medicinal Chemistry. Dec, 2008  |   Pubmed ID: 18608772
• A Profiling Platform for the Identification of Selective Metalloprotease Inhibitors
  Journal of Biomolecular Screening. Apr, 2008  |   Pubmed ID: 18349423
• Synthesis, Antileukemic and Antiplatelet Activities of 2,3-diaryl-6,7-dihydro-5H-1,4-diazepines
  European Journal of Medicinal Chemistry. Sep, 2008  |   Pubmed ID: 18191304
• Synthesis and Antiproliferative Activity of Some Diaryldiazepines and Diarylpyrimidines
  Journal of Enzyme Inhibition and Medicinal Chemistry. Dec, 2007  |   Pubmed ID: 18237024