Deniz Dalkara Department of Therapeutics, Institut de la Vision Sorbonne Universtés, UPMC Univ Paris 06, UMR_S 968 Biography Publications Institution JoVE Articles Deniz Dalkara has not added a biography. If you are Deniz Dalkara and would like to personalize this page please email our Author Liaison for assistance. Publications Gene Therapy for the Eye Focus on Mutation-independent Approaches Current Opinion in Neurology. Feb, 2015 | Pubmed ID: 25545056 Viral-mediated RdCVF and RdCVFL Expression Protects Cone and Rod Photoreceptors in Retinal Degeneration The Journal of Clinical Investigation. Jan, 2015 | Pubmed ID: 25415434 Targeting Channelrhodopsin-2 to ON-bipolar Cells with Vitreally Administered AAV Restores ON and OFF Visual Responses in Blind Mice Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2015 | Pubmed ID: 25095892 Intracisternal Delivery of NFκB-inducible ScAAV2/9 Reveals Locoregional Neuroinflammation Induced by Systemic Kainic Acid Treatment Frontiers in Molecular Neuroscience. 2014 | Pubmed ID: 25520614 Imaging Light Responses of Foveal Ganglion Cells in the Living Macaque Eye The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2014 | Pubmed ID: 24806684 Gene Therapy for Inherited Retinal Degenerations Comptes Rendus Biologies. Mar, 2014 | Pubmed ID: 24702845 Vertebrate Cone Opsins Enable Sustained and Highly Sensitive Rapid Control of Gi/o Signaling in Anxiety Circuitry Neuron. Mar, 2014 | Pubmed ID: 24656249 AAV-mediated Gene Delivery in Dp71-null Mouse Model with Compromised Barriers Glia. Mar, 2014 | Pubmed ID: 24382652 In Vivo-directed Evolution of a New Adeno-associated Virus for Therapeutic Outer Retinal Gene Delivery from the Vitreous Science Translational Medicine. Jun, 2013 | Pubmed ID: 23761039 Functional Rescue of Cone Photoreceptors in Retinitis Pigmentosa Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Jul, 2013 | Pubmed ID: 23575948 Long-distance Axonal Regeneration Induced by CNTF Gene Transfer is Impaired by Axonal Misguidance in the Injured Adult Optic Nerve Neurobiology of Disease. Mar, 2013 | Pubmed ID: 23194670 Systemic ScAAV9 Variant Mediates Brain Transduction in Newborn Rhesus Macaques Scientific Reports. 2012 | Pubmed ID: 22355765 Rapid Optical Control of Nociception with an Ion-channel Photoswitch Nature Methods. Apr, 2012 | Pubmed ID: 22343342 LiGluR Restores Visual Responses in Rodent Models of Inherited Blindness Molecular Therapy : the Journal of the American Society of Gene Therapy. Jul, 2011 | Pubmed ID: 21610698 AAV Mediated GDNF Secretion from Retinal Glia Slows Down Retinal Degeneration in a Rat Model of Retinitis Pigmentosa Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2011 | Pubmed ID: 21522134 Intravitreal Injection of AAV2 Transduces Macaque Inner Retina Investigative Ophthalmology & Visual Science. Apr, 2011 | Pubmed ID: 21310920 Changes in Adeno-associated Virus-mediated Gene Delivery in Retinal Degeneration Human Gene Therapy. May, 2010 | Pubmed ID: 20021232 A Novel Adeno-associated Viral Variant for Efficient and Selective Intravitreal Transduction of Rat Müller Cells PloS One. 2009 | Pubmed ID: 19826483 Inner Limiting Membrane Barriers to AAV-mediated Retinal Transduction from the Vitreous Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2009 | Pubmed ID: 19672248 Molecular Evolution of Adeno-associated Virus for Enhanced Glial Gene Delivery Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2009 | Pubmed ID: 19672246 Suppression of Cervical Carcinoma Cell Growth by Intracytoplasmic Codelivery of Anti-oncoprotein E6 Antibody and Small Interfering RNA Molecular Cancer Therapeutics. Jun, 2007 | Pubmed ID: 17575104 Intracellular Protein Delivery with a Dimerizable Amphiphile for Improved Complex Stability and Prolonged Protein Release in the Cytoplasm of Adherent Cell Lines Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2006 | Pubmed ID: 17097756 Cationic Oligonucleotide-peptide Conjugates with Aggregating Properties Enter Efficiently into Cells While Maintaining Hybridization Properties and Enzymatic Recognition Journal of the American Chemical Society. Aug, 2006 | Pubmed ID: 16910671 Intracytoplasmic Delivery of Anionic Proteins Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2004 | Pubmed ID: 15194063 Using Adeno-associated Virus as a Tool to Study Retinal Barriers in Disease Ophélie Vacca1,2,3, Brahim El Mathari1,2,3, Marie Darche1,2,3, José-Alain Sahel1,2,3, Alvaro Rendon1,2,3, Deniz Dalkara1,2,3 1Department of Therapeutics, Institut de la Vision, Sorbonne Universtés, UPMC Univ Paris 06, UMR_S 968, 2INSERM, U968, 3CNRS, UMR_7210 JoVE 52451 Medicine
Using Adeno-associated Virus as a Tool to Study Retinal Barriers in Disease Ophélie Vacca1,2,3, Brahim El Mathari1,2,3, Marie Darche1,2,3, José-Alain Sahel1,2,3, Alvaro Rendon1,2,3, Deniz Dalkara1,2,3 1Department of Therapeutics, Institut de la Vision, Sorbonne Universtés, UPMC Univ Paris 06, UMR_S 968, 2INSERM, U968, 3CNRS, UMR_7210 JoVE 52451 Medicine