Eng Eong Ooi Program in Emerging Infectious Diseases Duke-NUS Graduate Medical School Biography Publications Institution JoVE Articles Eng Eong Ooi has not added a biography. If you are Eng Eong Ooi and would like to personalize this page please email our Author Liaison for assistance. Publications Chikungunya and Dengue Fever Among Hospitalized Febrile Patients in Northern Tanzania The American Journal of Tropical Medicine and Hygiene. Jan, 2012 | Pubmed ID: 22232469 Dengue Virus Activates Polyreactive, Natural IgG B Cells After Primary and Secondary Infection PloS One. 2011 | Pubmed ID: 22216280 Economic Impact of Dengue Illness and the Cost-effectiveness of Future Vaccination Programs in Singapore PLoS Neglected Tropical Diseases. Dec, 2011 | Pubmed ID: 22206028 New Dengue Virus Type 1 Genotype in Colombo, Sri Lanka Emerging Infectious Diseases. Nov, 2011 | Pubmed ID: 22099096 Celgosivir Treatment Misfolds Dengue Virus NS1 Protein, Induces Cellular Pro-survival Genes and Protects Against Lethal Challenge Mouse Model Antiviral Research. Dec, 2011 | Pubmed ID: 22020302 Preparing for Introduction of a Dengue Vaccine: Recommendations from the 1st Dengue V2V Asia-Pacific Meeting Vaccine. Nov, 2011 | Pubmed ID: 21864627 Characterization of Early Host Responses in Adults with Dengue Disease BMC Infectious Diseases. 2011 | Pubmed ID: 21810247 Antimicrobial Activity of Cathelicidin Peptides Against Burkholderia Pseudomallei, the Causative Agent of Melioidosis International Journal of Antimicrobial Agents. Sep, 2011 | Pubmed ID: 21782393 Ligation of Fc Gamma Receptor IIB Inhibits Antibody-dependent Enhancement of Dengue Virus Infection Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21746897 The Early Clinical Features of Dengue in Adults: Challenges for Early Clinical Diagnosis PLoS Neglected Tropical Diseases. 2011 | Pubmed ID: 21655307 Chloroquine for Influenza Prevention: a Randomised, Double-blind, Placebo Controlled Trial The Lancet Infectious Diseases. Sep, 2011 | Pubmed ID: 21550310 Evaluation of the NS1 Rapid Test and the WHO Dengue Classification Schemes for Use As Bedside Diagnosis of Acute Dengue Fever in Adults The American Journal of Tropical Medicine and Hygiene. Feb, 2011 | Pubmed ID: 21292888 Unfolded Protein Response (UPR) Gene Expression During Antibody-dependent Enhanced Infection of Cultured Monocytes Correlates with Dengue Disease Severity Bioscience Reports. Jun, 2011 | Pubmed ID: 20858223 Update on Dengue: Epidemiology, Virus Evolution, Antiviral Drugs, and Vaccine Development Current Infectious Disease Reports. May, 2010 | Pubmed ID: 21308524 Contribution of Herpesvirus Specific CD8 T Cells to Anti-viral T Cell Response in Humans PLoS Pathogens. 2010 | Pubmed ID: 20808900 Activation of the Innate Immune System Provides Broad-spectrum Protection Against Influenza A Viruses with Pandemic Potential in Mice Virology. Oct, 2010 | Pubmed ID: 20667572 Influenza B Outbreak Among Influenza-vaccinated Welfare Home Residents in Singapore Annals of the Academy of Medicine, Singapore. Jun, 2010 | Pubmed ID: 20625620 A Method for Full Genome Sequencing of All Four Serotypes of the Dengue Virus Journal of Virological Methods. Oct, 2010 | Pubmed ID: 20600330 An Adjuvant for the Induction of Potent, Protective Humoral Responses to an H5N1 Influenza Virus Vaccine with Antigen-sparing Effect in Mice Journal of Virology. Sep, 2010 | Pubmed ID: 20538850 Multilocus Sequence Types of Carbapenem-resistant Pseudomonas Aeruginosa in Singapore Carrying Metallo-beta-lactamase Genes, Including the Novel Bla(IMP-26) Gene Journal of Clinical Microbiology. Jul, 2010 | Pubmed ID: 20463166 A Simple Method for Alexa Fluor Dye Labelling of Dengue Virus Journal of Virological Methods. Aug, 2010 | Pubmed ID: 20399231 A Label-free Immunosensor for Diagnosis of Dengue Infection with Simple Electrical Measurements Biosensors & Bioelectronics. Jan, 2010 | Pubmed ID: 19854635 Innate Immune Responses of Pulmonary Epithelial Cells to Burkholderia Pseudomallei Infection PloS One. 2009 | Pubmed ID: 19806192 Economic Analysis of Pandemic Influenza Vaccination Strategies in Singapore PloS One. 2009 | Pubmed ID: 19771173 Structural and Biological Diversity of Lipopolysaccharides from Burkholderia Pseudomallei and Burkholderia Thailandensis Clinical and Vaccine Immunology : CVI. Oct, 2009 | Pubmed ID: 19692625 Chikungunya in Singapore: Imported Cases Among Travelers Visiting Friends and Relatives Journal of Travel Medicine. Jul-Aug, 2009 | Pubmed ID: 19674272 Monkey Malaria in Humans: a Diagnostic Dilemma with Conflicting Laboratory Data The American Journal of Tropical Medicine and Hygiene. Jun, 2009 | Pubmed ID: 19478250 Dengue in Southeast Asia: Epidemiological Characteristics and Strategic Challenges in Disease Prevention Cadernos De Saúde Pública / Ministério Da Saúde, Fundação Oswaldo Cruz, Escola Nacional De Saúde Pública. 2009 | Pubmed ID: 19287856 Genomic Epidemiology of a Dengue Virus Epidemic in Urban Singapore Journal of Virology. May, 2009 | Pubmed ID: 19211734 IL-1beta, IL-6, and RANTES As Biomarkers of Chikungunya Severity PloS One. 2009 | Pubmed ID: 19156204 A TLR3 Ligand That Exhibits Potent Inhibition of Influenza Virus Replication and Has Strong Adjuvant Activity Has the Potential for Dual Applications in an Influenza Pandemic Vaccine. Feb, 2009 | Pubmed ID: 19150474 Neutralizing Human Monoclonal Antibody Against H5N1 Influenza HA Selected from a Fab-phage Display Library Virology Journal. 2008 | Pubmed ID: 18957074 The Core and Accessory Genomes of Burkholderia Pseudomallei: Implications for Human Melioidosis PLoS Pathogens. Oct, 2008 | Pubmed ID: 18927621 Epitope Characterization of the Protective Monoclonal Antibody VN04-2 Shows Broadly Neutralizing Activity Against Highly Pathogenic H5N1 Virology Journal. 2008 | Pubmed ID: 18616831 Naturally Acquired Human Plasmodium Knowlesi Infection, Singapore Emerging Infectious Diseases. May, 2008 | Pubmed ID: 18439370 Reconstructing Historical Changes in the Force of Infection of Dengue Fever in Singapore: Implications for Surveillance and Control Bulletin of the World Health Organization. Mar, 2008 | Pubmed ID: 18368205 Burkholderia Pseudomallei Aerosol Infection Results in Differential Inflammatory Responses in BALB/c and C57Bl/6 Mice Journal of Medical Microbiology. Apr, 2008 | Pubmed ID: 18349373 Decision Tree Algorithms Predict the Diagnosis and Outcome of Dengue Fever in the Early Phase of Illness PLoS Neglected Tropical Diseases. 2008 | Pubmed ID: 18335069 Pre- and Post-exposure Prophylaxis of Experimental Burkholderia Pseudomallei Infection with Doxycycline, Amoxicillin/clavulanic Acid and Co-trimoxazole The Journal of Antimicrobial Chemotherapy. Mar, 2008 | Pubmed ID: 18192684 Development of Real-time PCR Assays and Evaluation of Their Potential Use for Rapid Detection of Burkholderia Pseudomallei in Clinical Blood Specimens Journal of Clinical Microbiology. Sep, 2007 | Pubmed ID: 17634296 Cost-effective Real-time Reverse Transcriptase PCR (RT-PCR) to Screen for Dengue Virus Followed by Rapid Single-tube Multiplex RT-PCR for Serotyping of the Virus Journal of Clinical Microbiology. Mar, 2007 | Pubmed ID: 17215345 Early Dengue Infection and Outcome Study (EDEN) - Study Design and Preliminary Findings Annals of the Academy of Medicine, Singapore. Nov, 2006 | Pubmed ID: 17160194 A Prospective Clinical Study on the Use of Reverse Transcription-polymerase Chain Reaction for the Early Diagnosis of Dengue Fever The Journal of Molecular Diagnostics : JMD. Nov, 2006 | Pubmed ID: 17065431 Passive Immunoprophylaxis and Therapy with Humanized Monoclonal Antibody Specific for Influenza A H5 Hemagglutinin in Mice Respiratory Research. 2006 | Pubmed ID: 17040574 Antibiotic Susceptibility of 50 Clinical Isolates of Burkholderia Pseudomallei from Singapore The Journal of Antimicrobial Chemotherapy. Nov, 2006 | Pubmed ID: 16951412 In Vitro Inhibition of Human Influenza A Virus Replication by Chloroquine Virology Journal. 2006 | Pubmed ID: 16729896 Japanese Encephalitis, Singapore Emerging Infectious Diseases. Mar, 2006 | Pubmed ID: 16710983 Dengue Prevention and 35 Years of Vector Control in Singapore Emerging Infectious Diseases. Jun, 2006 | Pubmed ID: 16707042 Rapid Molecular Typing of Burkholderia Pseudomallei, Isolated in an Outbreak of Melioidosis in Singapore in 2004, Based on Variable-number Tandem Repeats Transactions of the Royal Society of Tropical Medicine and Hygiene. Jul, 2006 | Pubmed ID: 16343569 The Performance of RT-PCR Compared with a Rapid Serological Assay for Acute Dengue Fever in a Diagnostic Laboratory Transactions of the Royal Society of Tropical Medicine and Hygiene. Feb, 2006 | Pubmed ID: 16212996 An Outbreak of Primary Dengue Infection Among Migrant Chinese Workers in Singapore Characterized by Prominent Gastrointestinal Symptoms and a High Proportion of Symptomatic Cases Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology. Aug, 2005 | Pubmed ID: 16036184 Surveillance, Prevention, and Control of Legionellosis in a Tropical City-state American Journal of Infection Control. Jun, 2005 | Pubmed ID: 15947745 South-Asian Tsunami Lancet. Mar 12-18, 2005 | Pubmed ID: 15766984 Novel Immunofluorescence Assay Using Recombinant Nucleocapsid-spike Fusion Protein As Antigen to Detect Antibodies Against Severe Acute Respiratory Syndrome Coronavirus Clinical and Diagnostic Laboratory Immunology. Feb, 2005 | Pubmed ID: 15699428 Seroepidemiology of Neutralizing Antibodies to Japanese Encephalitis Virus in Singapore: Continued Transmission Despite Abolishment of Pig Farming? Acta Tropica. Nov-Dec, 2004 | Pubmed ID: 15533286 A Human in Vitro Model System for Investigating Genome-wide Host Responses to SARS Coronavirus Infection BMC Infectious Diseases. Sep, 2004 | Pubmed ID: 15357874 Mutational Dynamics of the SARS Coronavirus in Cell Culture and Human Populations Isolated in 2003 BMC Infectious Diseases. Sep, 2004 | Pubmed ID: 15347429 Characterization of a Unique Group-specific Protein (U122) of the Severe Acute Respiratory Syndrome Coronavirus Journal of Virology. Jul, 2004 | Pubmed ID: 15220404 Inhibition of SARS Coronavirus Infection in Vitro with Clinically Approved Antiviral Drugs Emerging Infectious Diseases. Apr, 2004 | Pubmed ID: 15200845 A Novel Severe Acute Respiratory Syndrome Coronavirus Protein, U274, is Transported to the Cell Surface and Undergoes Endocytosis Journal of Virology. Jul, 2004 | Pubmed ID: 15194747 Immunological Characterization of the Spike Protein of the Severe Acute Respiratory Syndrome Coronavirus Journal of Clinical Microbiology. Apr, 2004 | Pubmed ID: 15071006 Healthcare Worker Seroconversion in SARS Outbreak Emerging Infectious Diseases. Feb, 2004 | Pubmed ID: 15030691 Development of a Western Blot Assay for Detection of Antibodies Against Coronavirus Causing Severe Acute Respiratory Syndrome Clinical and Diagnostic Laboratory Immunology. Mar, 2004 | Pubmed ID: 15013997 Profiles of Antibody Responses Against Severe Acute Respiratory Syndrome Coronavirus Recombinant Proteins and Their Potential Use As Diagnostic Markers Clinical and Diagnostic Laboratory Immunology. Mar, 2004 | Pubmed ID: 15013989 Detection of Severe Acute Respiratory Syndrome Coronavirus in Blood of Infected Patients Journal of Clinical Microbiology. Jan, 2004 | Pubmed ID: 14715775 Effect of Increasing Age on the Trend of Dengue and Dengue Hemorrhagic Fever in Singapore International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases. Sep, 2003 | Pubmed ID: 14563228 Molecular Typing of Salmonella Enterica Serovar Typhi Isolates from Various Countries in Asia by a Multiplex PCR Assay on Variable-number Tandem Repeats Journal of Clinical Microbiology. Sep, 2003 | Pubmed ID: 12958274 Seroepidemiology of Human Enterovirus 71, Singapore Emerging Infectious Diseases. Sep, 2002 | Pubmed ID: 12194783 Presence of Hemagglutination Inhibition and Neutralization Antibodies to Japanese Encephalitis Virus in Wild Pigs on an Offshore Island in Singapore Acta Tropica. Mar, 2002 | Pubmed ID: 11835900 Visualizing Dengue Virus through Alexa Fluor Labeling Summer Zhang1, Hwee Cheng Tan2, Eng Eong Ooi3 1Defence Medical and Environmental Research Institute, DSO National Laboratories, 2Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, 3Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School JoVE 3168 Immunology and Infection
Visualizing Dengue Virus through Alexa Fluor Labeling Summer Zhang1, Hwee Cheng Tan2, Eng Eong Ooi3 1Defence Medical and Environmental Research Institute, DSO National Laboratories, 2Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, 3Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School JoVE 3168 Immunology and Infection