Eric A. Appel Materials Science & Engineering Stanford University Biography Publications Institution JoVE Articles Eric A. Appel Eric A. Appel is an Assistant Professor of Materials Science & Engineering at Stanford University. He received his BS in Chemistry and MS in Polymer Science from California Polytechnic in San Luis Obispo, CA. Eric performed his MS thesis research with Dr Jim Hedrick and Dr Robert Miller on the synthesis of polymers for drug delivery applications at the IBM Almaden Research Center in San Jose, CA. He then obtained his PhD in Chemistry with Prof. Oren A. Scherman in the Melville Laboratory for Polymer Synthesis at the University of Cambridge. His PhD research focused on the preparation of dynamic and stimuli-responsive supramolecular polymeric materials. For his PhD work, Eric was the recipient of the Jon Weaver PhD prize from the Royal Society of Chemistry and a Graduate Student Award from the Materials Research Society. Upon graduating from Cambridge in 2012, he was awarded a National Research Service Award from the NIH (NIBIB) and a Wellcome Trust Postdoctoral Fellowship to work with Prof. Robert Langer at MIT on the development of supramolecular biomaterials for applications in tissue engineering and drug delivery. During his post-doctoral work, he received a Margaret A. Cunningham Immune Mechanisms in Cancer Research Award. His work at Stanford focuses on the development of biomimetic polymeric materials that can be used as tools to better understand fundamental biological processes and to engineer advanced healthcare solutions. Publications Physical Networks from Entropy-driven Non-covalent Interactions Nature Communications. Feb, 2021 | Pubmed ID: 33531475 Seasonal Impact of Phosphate-Based Fire Retardants on Soil Chemistry Following the Prophylactic Treatment of Vegetation Environmental Science & Technology. Feb, 2021 | Pubmed ID: 33529000 Engineering Biopharmaceutical Formulations to Improve Diabetes Management Science Translational Medicine. Jan, 2021 | Pubmed ID: 33504649 Prolonged Codelivery of Hemagglutinin and a TLR7/8 Agonist in a Supramolecular Polymer-Nanoparticle Hydrogel Enhances Potency and Breadth of Influenza Vaccination ACS Biomaterials Science & Engineering. Jan, 2021 | Pubmed ID: 33404236 A Fluorescence Sandwich Immunoassay for the Real-time Continuous Detection of Glucose and Insulin in Live Animals Nature Biomedical Engineering. Jan, 2021 | Pubmed ID: 33349659 Highly Branched Polydimethylacrylamide Copolymers As Functional Biomaterials Biomacromolecules. Jan, 2021 | Pubmed ID: 32786733 MRBLES 2.0: High-throughput Generation of Chemically Functionalized Spectrally and Magnetically Encoded Hydrogel Beads Using a Simple Single-layer Microfluidic Device Microsystems & Nanoengineering. Month, 2020 | Pubmed ID: 33299601 A Quantitative Description for Designing the Extrudability of Shear-Thinning Physical Hydrogels Macromolecular Bioscience. Nov, 2020 | Pubmed ID: 33164332 Injectable Hydrogels for Sustained Codelivery of Subunit Vaccines Enhance Humoral Immunity ACS Central Science. Oct, 2020 | Pubmed ID: 33145416 Engineered Biomaterials for Heart Disease Current Opinion in Biotechnology. Dec, 2020 | Pubmed ID: 33011453 Nanoparticles Presenting Potent TLR7/8 Agonists Enhance Anti-PD-L1 Immunotherapy in Cancer Treatment Biomacromolecules. 09, 2020 | Pubmed ID: 32816460 Towards Brain-tissue-like Biomaterials Nature Communications. 07, 2020 | Pubmed ID: 32647269 An Ultrafast Insulin Formulation Enabled by High-throughput Screening of Engineered Polymeric Excipients Science Translational Medicine. Jul, 2020 | Pubmed ID: 32611683 Site-selective Modification of Proteins Using Cucurbit[7]uril As Supramolecular Protection for N-terminal Aromatic Amino Acids Organic & Biomolecular Chemistry. May, 2020 | Pubmed ID: 32459261 A Co-formulation of Supramolecularly Stabilized Insulin and Pramlintide Enhances Mealtime Glucagon Suppression in Diabetic Pigs Nature Biomedical Engineering. 05, 2020 | Pubmed ID: 32393892 Stable Monomeric Insulin Formulations Enabled by Supramolecular PEGylation of Insulin Analogues Advanced Therapeutics. Jan, 2020 | Pubmed ID: 32190729 Reply to Santín Et Al.: Viscoelastic Retardant Fluids Enable Treatments to Prevent Wildfire on Landscapes Subject to Routine Ignitions Proceedings of the National Academy of Sciences of the United States of America. 03, 2020 | Pubmed ID: 32079729 Injectable Supramolecular Polymer-nanoparticle Hydrogels Enhance Human Mesenchymal Stem Cell Delivery Bioengineering & Translational Medicine. Jan, 2020 | Pubmed ID: 31989036 Multi-phase Catheter-injectable Hydrogel Enables Dual-stage Protein-engineered Cytokine Release to Mitigate Adverse Left Ventricular Remodeling Following Myocardial Infarction in a Small Animal Model and a Large Animal Model Cytokine. 03, 2020 | Pubmed ID: 31978642 A Human Mission to Mars: Predicting the Bone Mineral Density Loss of Astronauts PloS One. Month, 2020 | Pubmed ID: 31967993 Universal Scaling Behavior During Network Formation in Controlled Radical Polymerizations Macromolecules. Dec, 2019 | Pubmed ID: 31894160 Injectable Polymer-Nanoparticle Hydrogels for Local Immune Cell Recruitment Biomacromolecules. 12, 2019 | Pubmed ID: 31682423 A Multiscale Model for Solute Diffusion in Hydrogels Macromolecules. Sep, 2019 | Pubmed ID: 31579160 Wildfire Prevention Through Prophylactic Treatment of High-risk Landscapes Using Viscoelastic Retardant Fluids Proceedings of the National Academy of Sciences of the United States of America. 10, 2019 | Pubmed ID: 31570592 Use of a Supramolecular Polymeric Hydrogel As an Effective Post-operative Pericardial Adhesion Barrier Nature Biomedical Engineering. 08, 2019 | Pubmed ID: 31391596 Block Copolymer Composition Drives Function of Self-assembled Nanoparticles for Delivery of Small-molecule Cargo Journal of Polymer Science. Part A, Polymer Chemistry. Jun, 2019 | Pubmed ID: 31244507 A Biocompatible Therapeutic Catheter-Deliverable Hydrogel for In Situ Tissue Engineering Advanced Healthcare Materials. 03, 2019 | Pubmed ID: 30714355 Non-Newtonian Polymer-Nanoparticle Hydrogels Enhance Cell Viability During Injection Macromolecular Bioscience. 01, 2019 | Pubmed ID: 30369048 Supramolecular Polymeric Biomaterials Biomaterials Science. Dec, 2017 | Pubmed ID: 29164196 Engineering the Mechanical Properties of Polymer Networks with Precise Doping of Primary Defects ACS Applied Materials & Interfaces. Dec, 2017 | Pubmed ID: 29135222 Mechanistic Understanding of in Vivo Protein Corona Formation on Polymeric Nanoparticles and Impact on Pharmacokinetics Nature Communications. 10, 2017 | Pubmed ID: 28974673 Decoupled Associative and Dissociative Processes in Strong Yet Highly Dynamic Host-Guest Complexes Journal of the American Chemical Society. 09, 2017 | Pubmed ID: 28661667 Single-Chain Polymeric Nanocarriers: A Platform for Determining Structure-Function Correlations in the Delivery of Molecular Cargo Biomacromolecules. 04, 2017 | Pubmed ID: 28263572 Scalable Manufacturing of Biomimetic Moldable Hydrogels for Industrial Applications Proceedings of the National Academy of Sciences of the United States of America. 12, 2016 | Pubmed ID: 27911849 Supramolecular Biomaterials Nature Materials. Jan, 2016 | Pubmed ID: 26681596 حقن فوق الجزيئية البوليمر نانوجسيمات هيدروجيلس لتطبيقات توصيل الخلايا والمخدرات Catherine M. Meis*1, Abigail K. Grosskopf*2, Santiago Correa1, Eric A. Appel1,3,4 1Department of Materials Science & Engineering, Stanford University, 2Department of Chemical Engineering, Stanford University, 3Department of Bioengineering, Stanford University, 4Department of Pediatrics - Endocrinology, Stanford University JoVE 62234 Bioengineering
حقن فوق الجزيئية البوليمر نانوجسيمات هيدروجيلس لتطبيقات توصيل الخلايا والمخدرات Catherine M. Meis*1, Abigail K. Grosskopf*2, Santiago Correa1, Eric A. Appel1,3,4 1Department of Materials Science & Engineering, Stanford University, 2Department of Chemical Engineering, Stanford University, 3Department of Bioengineering, Stanford University, 4Department of Pediatrics - Endocrinology, Stanford University JoVE 62234 Bioengineering