Francis Lin Department of Physics and Astronomy University of Manitoba Biography Publications Institution JoVE Articles Francis Lin has not added a biography. If you are Francis Lin and would like to personalize this page please email our Author Liaison for assistance. Publications Fibroblast Growth Factor 23 Weakens Chemotaxis of Human Blood Neutrophils in Microfluidic Devices Scientific Reports. Jun, 2017 | Pubmed ID: 28596573 The Effects of Activin A on the Migration of Human Breast Cancer Cells and Neutrophils and Their Migratory Interaction Experimental Cell Research. May, 2017 | Pubmed ID: 28479070 A Dual-docking Microfluidic Cell Migration Assay (D(2)-Chip) for Testing Neutrophil Chemotaxis and the Memory Effect Integrative Biology : Quantitative Biosciences from Nano to Macro. Apr, 2017 | Pubmed ID: 28367571 Rapid and Low-Cost CRP Measurement by Integrating a Paper-Based Microfluidic Immunoassay with Smartphone (CRP-Chip) Sensors (Basel, Switzerland). Mar, 2017 | Pubmed ID: 28346363 Toward All Room-Temperature, Solution-Processed, High-Performance Planar Perovskite Solar Cells: A New Scheme of Pyridine-Promoted Perovskite Formation Advanced Materials (Deerfield Beach, Fla.). Jan, 2017 | Pubmed ID: 28128871 Chemorepellent Semaphorin 3E Negatively Regulates Neutrophil Migration In Vitro and In Vivo Journal of Immunology (Baltimore, Md. : 1950). Feb, 2017 | Pubmed ID: 27913633 Enhanced Ambient Stability of Efficient Perovskite Solar Cells by Employing a Modified Fullerene Cathode Interlayer Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Sep, 2016 | Pubmed ID: 27711269 Microfluidic-Based Live-Cell Analysis of NK Cell Migration In Vitro Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 27177658 Novel Developments in Mobile Sensing Based on the Integration of Microfluidic Devices and Smartphones Lab on a Chip. Mar, 2016 | Pubmed ID: 26899264 Efficient Vacuum-Deposited Ternary Organic Solar Cells with Broad Absorption, Energy Transfer, and Enhanced Hole Mobility ACS Applied Materials & Interfaces. Jan, 2016 | Pubmed ID: 26714649 Phosphatidylinositol-3,4-Bisphosphate and Its Binding Protein Lamellipodin Regulate Chemotaxis of Malignant B Lymphocytes Journal of Immunology (Baltimore, Md. : 1950). Jan, 2016 | Pubmed ID: 26695371 Pinhole-Free and Surface-Nanostructured NiOx Film by Room-Temperature Solution Process for High-Performance Flexible Perovskite Solar Cells with Good Stability and Reproducibility ACS Nano. Jan, 2016 | Pubmed ID: 26688212 Neutrophil Migration Under Spatially-varying Chemoattractant Gradient Profiles Biomedical Microdevices. 2015 | Pubmed ID: 25998723 A Microfluidic Platform for Evaluating Neutrophil Chemotaxis Induced by Sputum from COPD Patients PloS One. 2015 | Pubmed ID: 25961597 Effectiveness of a Discharge Planning and Community Support Programme in Preventing Readmission of High-risk Older Patients Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi. Jun, 2015 | Pubmed ID: 25904292 Analysis of CCR7 Mediated T Cell Transfectant Migration Using a Microfluidic Gradient Generator Journal of Immunological Methods. Apr, 2015 | Pubmed ID: 25733353 Adipose-derived Stem Cells from Both Visceral and Subcutaneous Fat Deposits Significantly Improve Contractile Function of Infarcted Rat Hearts Cell Transplantation. 2015 | Pubmed ID: 25562327 Microfluidic-based, Live-cell Analysis Allows Assessment of NK-cell Migration in Response to Crosstalk with Dendritic Cells European Journal of Immunology. Sep, 2014 | Pubmed ID: 24954649 Recent Developments in Electrotaxis Assays Advances in Wound Care. Feb, 2014 | Pubmed ID: 24761355 A Compact Microfluidic System for Cell Migration Studies Biomedical Microdevices. Aug, 2014 | Pubmed ID: 24609918 Microcavity-embedded, Colour-tuneable, Transparent Organic Solar Cells Advanced Materials (Deerfield Beach, Fla.). Feb, 2014 | Pubmed ID: 24347466 Recent Developments in Microfluidics-based Chemotaxis Studies Lab on a Chip. Jul, 2013 | Pubmed ID: 23712326 DC Electric Fields Direct Breast Cancer Cell Migration, Induce EGFR Polarization, and Increase the Intracellular Level of Calcium Ions Cell Biochemistry and Biophysics. 2013 | Pubmed ID: 23657921 Effects of Clostridium Difficile Toxin A and B on Human T Lymphocyte Migration Toxins. May, 2013 | Pubmed ID: 23645153 The Tandem PH Domain-containing Protein 2 (TAPP2) Regulates Chemokine-induced Cytoskeletal Reorganization and Malignant B Cell Migration PloS One. 2013 | Pubmed ID: 23460911 Growth and Positioning of Adipose-derived Stem Cells in Microfluidic Devices Lab on a Chip. Nov, 2012 | Pubmed ID: 23007449 Vacuum-deposited Small-molecule Organic Solar Cells with High Power Conversion Efficiencies by Judicious Molecular Design and Device Optimization Journal of the American Chemical Society. Aug, 2012 | Pubmed ID: 22831172 Purification and Characterization of Alkaline Pectin Lyase from a Newly Isolated Bacillus Clausii and Its Application in Elicitation of Plant Disease Resistance Applied Biochemistry and Biotechnology. Aug, 2012 | Pubmed ID: 22695924 Microfluidic Device for Studying Cell Migration in Single or Co-existing Chemical Gradients and Electric Fields Biomicrofluidics. Jun, 2012 | Pubmed ID: 22670168 Device Engineering for Highly Efficient Top-illuminated Organic Solar Cells with Microcavity Structures Advanced Materials (Deerfield Beach, Fla.). May, 2012 | Pubmed ID: 22473611 E-cadherin Plays an Essential Role in Collective Directional Migration of Large Epithelial Sheets Cellular and Molecular Life Sciences : CMLS. Aug, 2012 | Pubmed ID: 22410739 A Donor-acceptor-acceptor Molecule for Vacuum-processed Organic Solar Cells with a Power Conversion Efficiency of 6.4% Chemical Communications (Cambridge, England). Feb, 2012 | Pubmed ID: 22167175 A Low-energy-gap Organic Dye for High-performance Small-molecule Organic Solar Cells Journal of the American Chemical Society. Oct, 2011 | Pubmed ID: 21905648 A Receptor-electromigration-based Model for Cellular Electrotactic Sensing and Migration Biochemical and Biophysical Research Communications. Aug, 2011 | Pubmed ID: 21782800 Microfluidic Devices for Studying Chemotaxis and Electrotaxis Trends in Cell Biology. Aug, 2011 | Pubmed ID: 21665472 Modeling Cell Gradient Sensing and Migration in Competing Chemoattractant Fields PloS One. 2011 | Pubmed ID: 21559528 Combinatorial Guidance by CCR7 Ligands for T Lymphocytes Migration in Co-existing Chemokine Fields PloS One. 2011 | Pubmed ID: 21464944 A New Spirobifluorene-bridged Bipolar System for a Nitric Oxide Turn-on Fluorescent Probe Organic Letters. May, 2011 | Pubmed ID: 21446738 Microfluidics for Food, Agriculture and Biosystems Industries Lab on a Chip. May, 2011 | Pubmed ID: 21431239 Activated T Lymphocytes Migrate Toward the Cathode of DC Electric Fields in Microfluidic Devices Lab on a Chip. Apr, 2011 | Pubmed ID: 21327249 Chapter 15. A Microfluidics-based Method for Chemoattractant Gradients Methods in Enzymology. 2009 | Pubmed ID: 19480926 Modeling the Role of Homologous Receptor Desensitization in Cell Gradient Sensing Journal of Immunology (Baltimore, Md. : 1950). Dec, 2008 | Pubmed ID: 19050250 Lymphocyte Electrotaxis in Vitro and in Vivo Journal of Immunology (Baltimore, Md. : 1950). Aug, 2008 | Pubmed ID: 18684937 Generation of Stable Concentration Gradients in 2D and 3D Environments Using a Microfluidic Ladder Chamber Biomedical Microdevices. Oct, 2007 | Pubmed ID: 17530414 T Cell Chemotaxis in a Simple Microfluidic Device Lab on a Chip. Nov, 2006 | Pubmed ID: 17066171 A Microfluidic Multi-injector for Gradient Generation Lab on a Chip. Jun, 2006 | Pubmed ID: 16738728 A Parallel-gradient Microfluidic Chamber for Quantitative Analysis of Breast Cancer Cell Chemotaxis Biomedical Microdevices. Jun, 2006 | Pubmed ID: 16688570 Neutrophil Migration in Opposing Chemoattractant Gradients Using Microfluidic Chemotaxis Devices Annals of Biomedical Engineering. Apr, 2005 | Pubmed ID: 15909653 Differential Effects of EGF Gradient Profiles on MDA-MB-231 Breast Cancer Cell Chemotaxis Experimental Cell Research. Oct, 2004 | Pubmed ID: 15383325 Intracellular Actin-based Transport: How Far You Go Depends on How Often You Switch Proceedings of the National Academy of Sciences of the United States of America. Sep, 2004 | Pubmed ID: 15331778 Effective Neutrophil Chemotaxis is Strongly Influenced by Mean IL-8 Concentration Biochemical and Biophysical Research Communications. Jun, 2004 | Pubmed ID: 15178445 Generation of Dynamic Temporal and Spatial Concentration Gradients Using Microfluidic Devices Lab on a Chip. Jun, 2004 | Pubmed ID: 15159771 An All-on-chip Method for Rapid Neutrophil Chemotaxis Analysis Directly from a Drop of Blood Ke Yang*1,2,3, Jiandong Wu*3,4, Ling Zhu1, Yong Liu1, Michael Zhang5, Francis Lin3,4,6,7 1Institute of Applied Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 2University of Science and Technology of China, 3Department of Physics and Astronomy, University of Manitoba, 4Department of Biosystems Engineering, University of Manitoba, 5Seven Oaks General Hospital, 6Department of Immunology, University of Manitoba, 7Department of Biological Sciences, University of Manitoba JoVE 55615 Immunology and Infection A Gradient-generating Microfluidic Device for Cell Biology Bong Geun Chung1, Amir Manbachi1, Wajeeh Saadi1, Francis Lin1, Noo Li Jeon1, Ali Khademhosseini1 1Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology; Center for Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital JoVE 271 Biology
An All-on-chip Method for Rapid Neutrophil Chemotaxis Analysis Directly from a Drop of Blood Ke Yang*1,2,3, Jiandong Wu*3,4, Ling Zhu1, Yong Liu1, Michael Zhang5, Francis Lin3,4,6,7 1Institute of Applied Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 2University of Science and Technology of China, 3Department of Physics and Astronomy, University of Manitoba, 4Department of Biosystems Engineering, University of Manitoba, 5Seven Oaks General Hospital, 6Department of Immunology, University of Manitoba, 7Department of Biological Sciences, University of Manitoba JoVE 55615 Immunology and Infection
A Gradient-generating Microfluidic Device for Cell Biology Bong Geun Chung1, Amir Manbachi1, Wajeeh Saadi1, Francis Lin1, Noo Li Jeon1, Ali Khademhosseini1 1Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology; Center for Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital JoVE 271 Biology