Huijun SUn

Publications

• Activation of PGC-1α Via Isoliquiritigenin-induced Downregulation of MiR-138-5p Alleviates Nonalcoholic Fatty Liver Disease
  Phytotherapy Research : PTR. Jan, 2022   |   Pubmed ID: 35041255
• Isoliquiritigenin-mediated MiR-23a-3p Inhibition Activates PGC-1α to Alleviate Alcoholic Liver Injury
  Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. Feb, 2022   |   Pubmed ID: 34785106
• Identifying the Dominant Contribution of Human Cytochrome P450 2J2 to the Metabolism of Rivaroxaban, an Oral Anticoagulant
  Cardiovascular Drugs and Therapy. Feb, 2022   |   Pubmed ID: 33411110
• Isoliquiritigenin Alleviates LPS/ D-GalN-induced Acute Liver Failure by Activating the PGC-1α/ Nrf2 Pathway to Reduce Oxidative Stress and Inflammatory Response
  International Immunopharmacology. Nov, 2021   |   Pubmed ID: 34555641
• In Vitro Measurement and In Vivo Prediction of Time-Dependent Inhibitory Effects of Three Tyrosine Kinase Inhibitors on CYP3A Activity
  Current Drug Metabolism. Month, 2021   |   Pubmed ID: 34473615
• Kaempferol-induced GPER Upregulation Attenuates Atherosclerosis Via the PI3K/AKT/Nrf2 Pathway
  Pharmaceutical Biology. Dec, 2021   |   Pubmed ID: 34403325
• Yangonin Modulates Lipid Homeostasis, Ameliorates Cholestasis and Cellular Senescence in Alcoholic Liver Disease Via Activating Nuclear Receptor FXR
  Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. Sep, 2021   |   Pubmed ID: 34304130
• Noncovalent EGFR T790M/L858R Inhibitors Based on Diphenylpyrimidine Scaffold: Design, Synthesis, and Bioactivity Evaluation for the Treatment of NSCLC
  European Journal of Medicinal Chemistry. Nov, 2021   |   Pubmed ID: 34218082
• Synthesis and Biological Evaluation of Selenogefitinib for Reducing Bleomycin-induced Pulmonary Fibrosis
  Bioorganic & Medicinal Chemistry Letters. 09, 2021   |   Pubmed ID: 34216747
• Luteolin Ameliorates LPS-induced Acute Liver Injury by Inhibiting TXNIP-NLRP3 Inflammasome in Mice
  Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. Jul, 2021   |   Pubmed ID: 34044253
• Comparison of the Inhibitory Effects of Clotrimazole and Ketoconazole Against Human Carboxylesterase 2
  Current Drug Metabolism. Month, 2021   |   Pubmed ID: 33568030
• Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity Through the Mitochondrial-Dependent Pathway Without Compromising Its Anticancer Properties
  Oxidative Medicine and Cellular Longevity. Month, 2021   |   Pubmed ID: 33510841
• Synthesis and Biological Activity of Imidazole Group-substituted Arylaminopyrimidines (IAAPs) As Potent BTK Inhibitors Against B-cell Lymphoma and AML
  Bioorganic Chemistry. 01, 2021   |   Pubmed ID: 33272709
• Phosphocreatine Promotes Osteoblastic Activities in HO-Induced MC3T3-E1 Cells by Regulating SIRT1/FOXO1/PGC-1α Signaling Pathway
  Current Pharmaceutical Biotechnology. Month, 2021   |   Pubmed ID: 33198615
• Puerarin Sensitized K562/ADR Cells by Inhibiting NF-κB Pathway and Inducing Autophagy
  Phytotherapy Research : PTR. Mar, 2021   |   Pubmed ID: 33141989
• Yangonin Inhibits Ethanol-induced Hepatocyte Senescence Via MiR-194/FXR Axis
  European Journal of Pharmacology. Jan, 2021   |   Pubmed ID: 33068587
• Rosmarinic Acid Exerts an Antagonistic Effect on Nonalcoholic Fatty Liver Disease by Regulating the YAP1/TAZ-PPARγ/PGC-1α Signaling Pathway
  Phytotherapy Research : PTR. Feb, 2021   |   Pubmed ID: 32914480
• Author Correction: Potent Effects of Dioscin Against Obesity in Mice
  Scientific Reports. Oct, 2020   |   Pubmed ID: 33093537
• CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism
  Frontiers in Pharmacology. Month, 2020   |   Pubmed ID: 32792941
• Targeting Renal OATs to Develop Renal Protective Agent from Traditional Chinese Medicines: Protective Effect of Apigenin Against Imipenem-induced Nephrotoxicity
  Phytotherapy Research : PTR. Nov, 2020   |   Pubmed ID: 32468621
• Organic Anion Transporters Also Mediate the Drug-drug Interaction Between Imipenem and Cilastatin
  Asian Journal of Pharmaceutical Sciences. Mar, 2020   |   Pubmed ID: 32373203
• Molecular Pharmacokinetic Mechanism of the Drug-drug Interaction Between Genistein and Repaglinide Mediated by P-gp
  Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. May, 2020   |   Pubmed ID: 32187961
• A Review of the Anti-Inflammatory Effects of Rosmarinic Acid on Inflammatory Diseases
  Frontiers in Pharmacology. Month, 2020   |   Pubmed ID: 32184728
• Macrophage-derived MMP-9 Enhances the Progression of Atherosclerotic Lesions and Vascular Calcification in Transgenic Rabbits
  Journal of Cellular and Molecular Medicine. 04, 2020   |   Pubmed ID: 32126159
• Targeting of MiR-96-5p by Catalpol Ameliorates Oxidative Stress and Hepatic Steatosis in LDLr-/- Mice Via P66shc/cytochrome C Cascade
  Aging. 02, 2020   |   Pubmed ID: 32023549
• Protective Effect of Cilastatin Against Diclofenac-induced Nephrotoxicity Through Interaction with Diclofenac Acyl Glucuronide Via Organic Anion Transporters
  British Journal of Pharmacology. 05, 2020   |   Pubmed ID: 32000294
• Corrigendum to "Disocin Prevents Postmenopausal Atherosclerosis in Ovariectomized LDLR-/mice Through a PGC-1α/ERα Pathway Leading to Promotion of Autophagy and Inhibition of Oxidative Stress, Inflammation and Apoptosis" [Pharmacol. Res. 148 (2019) 104414]
  Pharmacological Research. Mar, 2020   |   Pubmed ID: 31926782
• Synthesis and Biological Activity of Thieno[3,2-d]pyrimidines As Potent JAK3 Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis
  Bioorganic & Medicinal Chemistry. 01, 2020   |   Pubmed ID: 31866272
• Corrigendum to "Dioscin Reduces Ovariectomy-induced Bone Loss by Enhancing Osteoblastogenesis and Inhibiting Osteoclastogenesis" [Pharmacol. Res. 108 (2016) 90-101]
  Pharmacological Research. Jan, 2020   |   Pubmed ID: 31780339
• Organic Anion Transporters and PI3K-AKT-mTOR Pathway Mediate the Synergistic Anticancer Effect of Pemetrexed and Rhein
  Journal of Cellular Physiology. 04, 2020   |   Pubmed ID: 31587272
• Piperacillin Enhances the Inhibitory Effect of Tazobactam on β-lactamase Through Inhibition of Organic Anion Transporter 1/3 in Rats
  Asian Journal of Pharmaceutical Sciences. Nov, 2019   |   Pubmed ID: 32104494
• Biomineralized Gd O @HSA Nanoparticles As a Versatile Platform for Dual-Modal Imaging and Chemo-Phototherapy-Synergized Tumor Ablation
  Advanced Healthcare Materials. 12, 2019   |   Pubmed ID: 31738019
• Corrigendum to "Dioscin Attenuates Renal Ischemia/reperfusion Injury by Inhibiting TheTLR4/MyD88 Signaling Pathway Via Up-regulation of HSP70" [Pharmacol. Res. 100 (2015) 341-352]
  Pharmacological Research. Dec, 2019   |   Pubmed ID: 31699473
• Cilastatin Protects Against Imipenem-induced Nephrotoxicity Inhibition of Renal Organic Anion Transporters (OATs)
  Acta Pharmaceutica Sinica. B. Sep, 2019   |   Pubmed ID: 31649848
• Hepatoprotection of Yangonin Against Hepatic Fibrosis in Mice Via Farnesoid X Receptor Activation
  International Immunopharmacology. Oct, 2019   |   Pubmed ID: 31450152
• Disocin Prevents Postmenopausal Atherosclerosis in Ovariectomized LDLR-/- Mice Through a PGC-1α/ERα Pathway Leading to Promotion of Autophagy and Inhibition of Oxidative Stress, Inflammation and Apoptosis
  Pharmacological Research. 10, 2019   |   Pubmed ID: 31449974
• Catalpol Alleviates Adriamycin-induced Nephropathy by Activating the SIRT1 Signalling Pathway in Vivo and in Vitro
  British Journal of Pharmacology. 12, 2019   |   Pubmed ID: 31378931
• Yangonin Protects Against Estrogen-induced Cholestasis in a Farnesoid X Receptor-dependent Manner
  European Journal of Pharmacology. Aug, 2019   |   Pubmed ID: 31220436
• An Interspecies Study of Lipid Profiles and Atherosclerosis in Familial Hypercholesterolemia Animal Models with Low-density Lipoprotein Receptor Deficiency
  American Journal of Translational Research. Month, 2019   |   Pubmed ID: 31217881
• Hepatoprotection of Auraptene from the Peels of Citrus Fruits Against 17α-ethinylestradiol-induced Cholestasis in Mice by Activating Farnesoid X Receptor
  Food & Function. Jul, 2019   |   Pubmed ID: 31210195
• Scutellarin Exerts Protective Effects Against Atherosclerosis in Rats by Regulating the Hippo-FOXO3A and PI3K/AKT Signaling Pathways
  Journal of Cellular Physiology. 08, 2019   |   Pubmed ID: 30891776
• Rosmarinic Acid Exerts an Antagonistic Effect on Vascular Calcification by Regulating the Nrf2 Signalling Pathway
  Free Radical Research. Feb, 2019   |   Pubmed ID: 30864863
• Potent Effects of Dioscin Against Hepatocellular Carcinoma Through Regulating TP53-induced Glycolysis and Apoptosis Regulator (TIGAR)-mediated Apoptosis, Autophagy, and DNA Damage
  British Journal of Pharmacology. 04, 2019   |   Pubmed ID: 30710454
• Facile Synthesis of Fluorescent Carbon Dots from Prunus Cerasifera Fruits for Fluorescent Ink, Fe Ion Detection and Cell Imaging
  Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy. Apr, 2019   |   Pubmed ID: 30703711
• Yangonin Protects Against Non-alcoholic Fatty Liver Disease Through Farnesoid X Receptor
  Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. Feb, 2019   |   Pubmed ID: 30668392
• Resveratrol Enhances the Protective Effects of JBP485 Against Indomethacin-induced Rat Intestinal Damage in Vivo and Vitro Through Up-regulating Oligopeptide Transporter 1 (Pept1)
  Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Mar, 2019   |   Pubmed ID: 30590313
• Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation Via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells
  Inflammation. Feb, 2019   |   Pubmed ID: 30315526
• Luteolin Attenuates Glucocorticoid-induced Osteoporosis by Regulating ERK/Lrp-5/GSK-3β Signaling Pathway in Vivo and in Vitro
  Journal of Cellular Physiology. 04, 2019   |   Pubmed ID: 30192012
• Combination of Dihydromyricetin and Ondansetron Strengthens Antiproliferative Efficiency of Adriamycin in K562/ADR Through Downregulation of SORCIN: A New Strategy of Inhibiting P-glycoprotein
  Journal of Cellular Physiology. 04, 2019   |   Pubmed ID: 30171603
• MiR-125a-5p Ameliorates Hepatic Glycolipid Metabolism Disorder in Type 2 Diabetes Mellitus Through Targeting of STAT3
  Theranostics. Month, 2018   |   Pubmed ID: 30555566
• Targeting P-Glycoprotein: Nelfinavir Reverses Adriamycin Resistance in K562/ADR Cells
  Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. Month, 2018   |   Pubmed ID: 30497065
• Protective Effects of Dioscin Against Cartilage Destruction in a Monosodium Iodoacetate (MIA)-indcued Osteoarthritis Rat Model
  Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Dec, 2018   |   Pubmed ID: 30372803
• Involvement of Organic Cation Transporter 2 in the Metformin-associated Increased Lactate Levels Caused by Contrast-induced Nephropathy
  Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Oct, 2018   |   Pubmed ID: 30119251
• Pharmacokinetic Changes of Cefdinir and Cefditoren and Its Molecular Mechanisms in Acute Kidney Injury in Rats
  The Journal of Pharmacy and Pharmacology. Nov, 2018   |   Pubmed ID: 30047127
• Activating the PGC-1/TERT Pathway by Catalpol Ameliorates Atherosclerosis Via Modulating ROS Production, DNA Damage, and Telomere Function: Implications on Mitochondria and Telomere Link
  Oxidative Medicine and Cellular Longevity. Month, 2018   |   Pubmed ID: 30046372
• Hepatoprotective Effect of Rhein Against Methotrexate-induced Liver Toxicity
  European Journal of Pharmacology. Sep, 2018   |   Pubmed ID: 30031796
• Structural Optimization of Diphenylpyrimidine Scaffold As Potent and Selective Epidermal Growth Factor Receptor Inhibitors Against L858R/T790M Resistance Mutation in Nonsmall Cell Lung Cancer
  Chemical Biology & Drug Design. 12, 2018   |   Pubmed ID: 30030903
• Ginsenoside Rg1 Protects Against Acetaminophen-induced Liver Injury Via Activating Nrf2 Signaling Pathway in Vivo and in Vitro
  Regulatory Toxicology and Pharmacology : RTP. Oct, 2018   |   Pubmed ID: 30030101
• Novel Amino Acid-substituted Diphenylpyrimidine Derivatives As Potent BTK Inhibitors Against B Cell Lymphoma Cell Lines
  Bioorganic & Medicinal Chemistry. 08, 2018   |   Pubmed ID: 30006143
• Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice
  Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. Month, 2018   |   Pubmed ID: 29975924
• Hepatoprotective Effect of Ginsenoside Rg1 from Panax Ginseng on Carbon Tetrachloride-induced Acute Liver Injury by Activating Nrf2 Signaling Pathway in Mice
  Environmental Toxicology. Oct, 2018   |   Pubmed ID: 29964319
• JBP485 Attenuates Vancomycin-induced Nephrotoxicity by Regulating the Expressions of Organic Anion Transporter (Oat) 1, Oat3, Organic Cation Transporter 2 (Oct2), Multidrug Resistance-associated Protein 2 (Mrp2) and P-glycoprotein (P-gp) in Rats
  Toxicology Letters. Oct, 2018   |   Pubmed ID: 29964132
• MicroRNA-351-5p Aggravates Intestinal Ischaemia/reperfusion Injury Through the Targeting of MAPK13 and Sirtuin-6
  British Journal of Pharmacology. 09, 2018   |   Pubmed ID: 29952043
• Protective Effects of Ginsenoside Rg1 Against Lipopolysaccharide/d-galactosamine-induced Acute Liver Injury in Mice Through Inhibiting Toll-like Receptor 4 Signaling Pathway
  International Immunopharmacology. Aug, 2018   |   Pubmed ID: 29902710
• Hepatoprotection of Auraptene from Peels of Citrus Fruits Against Thioacetamide-induced Hepatic Fibrosis in Mice by Activating Farnesoid X Receptor
  Food & Function. May, 2018   |   Pubmed ID: 29721568
• Puerarin Improves Methotrexate-induced Renal Damage by Up-regulating Renal Expression of Oat1 and Oat3 in Vivo and in Vitro
  Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Jul, 2018   |   Pubmed ID: 29710508
• Icariin Promotes Stable Chondrogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in Self‑assembling Peptide Nanofiber Hydrogel Scaffolds
  Molecular Medicine Reports. Jun, 2018   |   Pubmed ID: 29693145
• Yangonin Protects Against Cholestasis and Hepatotoxity Via Activation of Farnesoid X Receptor in Vivo and in Vitro
  Toxicology and Applied Pharmacology. 06, 2018   |   Pubmed ID: 29660435
• P-gp is Involved in the Intestinal Absorption and Biliary Excretion of Afatinib in Vitro and in Rats
  Pharmacological Reports : PR. Apr, 2018   |   Pubmed ID: 29475007
• Protective Effects of Yangonin from an Edible Botanical Kava Against Lithocholic Acid-induced Cholestasis and Hepatotoxicity
  European Journal of Pharmacology. Apr, 2018   |   Pubmed ID: 29427579
• Scutellarin Ameliorates Nonalcoholic Fatty Liver Disease Through the PPARγ/PGC-1α-Nrf2 Pathway
  Free Radical Research. Feb, 2018   |   Pubmed ID: 29400110
• Catalpol Ameliorates Hepatic Insulin Resistance in Type 2 Diabetes Through Acting on AMPK/NOX4/PI3K/AKT Pathway
  Pharmacological Research. 04, 2018   |   Pubmed ID: 29284152
• OAT1 and OAT3 Also Mediate the Drug-drug Interaction Between Piperacillin and Tazobactam
  International Journal of Pharmaceutics. Feb, 2018   |   Pubmed ID: 29277663
• Effects of Calycosin Against High-fat Diet-induced Nonalcoholic Fatty Liver Disease in Mice
  Journal of Gastroenterology and Hepatology. Feb, 2018   |   Pubmed ID: 28699662
• Targeting P-glycoprotein and SORCIN: Dihydromyricetin Strengthens Anti-proliferative Efficiency of Adriamycin Via MAPK/ERK and Ca -mediated Apoptosis Pathways in MCF-7/ADR and K562/ADR
  Journal of Cellular Physiology. 04, 2018   |   Pubmed ID: 28681913
• Computational Discovery and Experimental Verification of Farnesoid X Receptor Agonist Auraptene to Protect Against Cholestatic Liver Injury
  Biochemical Pharmacology. 12, 2017   |   Pubmed ID: 28987596
• Organic Anion-Transporting Polypeptide and Efflux Transporter-Mediated Hepatic Uptake and Biliary Excretion of Cilostazol and Its Metabolites in Rats and Humans
  Journal of Pharmaceutical Sciences. 09, 2017   |   Pubmed ID: 28535976
• Protective Effects of Glycyrrhizic Acid Against Non-alcoholic Fatty Liver Disease in Mice
  European Journal of Pharmacology. Jul, 2017   |   Pubmed ID: 28414056
• Targeting Oct2 and P53: Formononetin Prevents Cisplatin-induced Acute Kidney Injury
  Toxicology and Applied Pharmacology. 07, 2017   |   Pubmed ID: 28414026
• Protective Effects of Dioscin Against Lipopolysaccharide-Induced Acute Lung Injury Through Inhibition of Oxidative Stress and Inflammation
  Frontiers in Pharmacology. Month, 2017   |   Pubmed ID: 28377715
• Calycosin Attenuates Triglyceride Accumulation and Hepatic Fibrosis in Murine Model of Non-alcoholic Steatohepatitis Via Activating Farnesoid X Receptor
  Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. Feb, 2017   |   Pubmed ID: 28190475
• Targeting P-glycoprotein Function, P53 and Energy Metabolism: Combination of Metformin and 2-deoxyglucose Reverses the Multidrug Resistance of MCF-7/Dox Cells to Doxorubicin
  Oncotarget. Jan, 2017   |   Pubmed ID: 28052008
• Design and Synthesis of Phosphoryl-substituted Diphenylpyrimidines (Pho-DPPYs) As Potent Bruton's Tyrosine Kinase (BTK) Inhibitors: Targeted Treatment of B Lymphoblastic Leukemia Cell Lines
  Bioorganic & Medicinal Chemistry. 01, 2017   |   Pubmed ID: 27956037
• Protective Effects of Glycyrrhizic Acid from Edible Botanical Glycyrrhiza Glabra Against Non-alcoholic Steatohepatitis in Mice
  Food & Function. Sep, 2016   |   Pubmed ID: 27487733
• Dioscin Alleviates Lipopolysaccharide-induced Inflammatory Kidney Injury Via the MicroRNA Let-7i/TLR4/MyD88 Signaling Pathway
  Pharmacological Research. 09, 2016   |   Pubmed ID: 27431331
• P-gp, MRP2 and OAT1/OAT3 Mediate the Drug-drug Interaction Between Resveratrol and Methotrexate
  Toxicology and Applied Pharmacology. 09, 2016   |   Pubmed ID: 27377006
• Dioscin Strengthens the Efficiency of Adriamycin in MCF-7 and MCF-7/ADR Cells Through Autophagy Induction: More Than Just Down-regulation of MDR1
  Scientific Reports. 06, 2016   |   Pubmed ID: 27329817
• Dioscin Protects Against ANIT-induced Cholestasis Via Regulating Oatps, Mrp2 and Bsep Expression in Rats
  Toxicology and Applied Pharmacology. 08, 2016   |   Pubmed ID: 27317372
• Dioscin Reduces Ovariectomy-induced Bone Loss by Enhancing Osteoblastogenesis and Inhibiting Osteoclastogenesis
  Pharmacological Research. 06, 2016   |   Pubmed ID: 27155058
• Alpha-lipoic Acid Defends Homocysteine-induced Endoplasmic Reticulum and Oxidative Stress in HAECs
  Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. May, 2016   |   Pubmed ID: 27133040
• Chondroprotective Effects of Alpha-lipoic Acid in a Rat Model of Osteoarthritis
  Free Radical Research. Jul, 2016   |   Pubmed ID: 27055478
• Targeting P-glycoprotein Expression and Cancer Cell Energy Metabolism: Combination of Metformin and 2-deoxyglucose Reverses the Multidrug Resistance of K562/Dox Cells to Doxorubicin
  Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine. Jul, 2016   |   Pubmed ID: 26733176
• Bezafibrate-mizoribine Interaction: Involvement of Organic Anion Transporters OAT1 and OAT3 in Rats
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Jan, 2016   |   Pubmed ID: 26474691
• Enhancement Effect of Resveratrol on the Intestinal Absorption of Bestatin by Regulating PEPT1, MDR1 and MRP2 in Vivo and in Vitro
  International Journal of Pharmaceutics. Nov, 2015   |   Pubmed ID: 26394120
• Dioscin Attenuates Renal Ischemia/reperfusion Injury by Inhibiting the TLR4/MyD88 Signaling Pathway Via Up-regulation of HSP70
  Pharmacological Research. Oct, 2015   |   Pubmed ID: 26348276
• Protective Effects of Alisol B 23-Acetate Via Farnesoid X Receptor-Mediated Regulation of Transporters and Enzymes in Estrogen-Induced Cholestatic Liver Injury in Mice
  Pharmaceutical Research. Nov, 2015   |   Pubmed ID: 26040663
• Potent Effects of Dioscin Against Liver Fibrosis
  Scientific Reports. Apr, 2015   |   Pubmed ID: 25853178
• Protective Effects of Alisol B 23-acetate from Edible Botanical Rhizoma Alismatis Against Carbon Tetrachloride-induced Hepatotoxicity in Mice
  Food & Function. Apr, 2015   |   Pubmed ID: 25747392
• Decreased Liver Distribution of Entecavir is Related to Down-regulation of Oat2/Oct1 and Up-regulation of Mrp1/2/3/5 in Rat Liver Fibrosis
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Apr, 2015   |   Pubmed ID: 25712368
• Potent Effects of Dioscin Against Obesity in Mice
  Scientific Reports. Jan, 2015   |   Pubmed ID: 25609476
• Potent Anti-inflammatory Effect of Dioscin Mediated by Suppression Of TNF-α-induced VCAM-1, ICAM-1and EL Expression Via the NF-κB Pathway
  Biochimie. Mar, 2015   |   Pubmed ID: 25577996
• Dasatinib Reverses the Multidrug Resistance of Breast Cancer MCF-7 Cells to Doxorubicin by Downregulating P-gp Expression Via Inhibiting the Activation of ERK Signaling Pathway
  Cancer Biology & Therapy. Month, 2015   |   Pubmed ID: 25482933
• Rhizoma Dioscoreae Nipponicae Polysaccharides Protect HUVECs from H2O2-induced Injury by Regulating PPARγ Factor and the NADPH Oxidase/ROS-NF-κB Signal Pathway
  Toxicology Letters. Jan, 2015   |   Pubmed ID: 25305479
• Protective Effects of Calycosin Against CCl4-induced Liver Injury with Activation of FXR and STAT3 in Mice
  Pharmaceutical Research. Feb, 2015   |   Pubmed ID: 25143196
• Naringin Inhibits TNF-α Induced Oxidative Stress and Inflammatory Response in HUVECs Via Nox4/NF-κ B and PI3K/Akt Pathways
  Current Pharmaceutical Biotechnology. Month, 2014   |   Pubmed ID: 25391245
• Alisol B 23-acetate Promotes Liver Regeneration in Mice After Partial Hepatectomy Via Activating Farnesoid X Receptor
  Biochemical Pharmacology. Nov, 2014   |   Pubmed ID: 25278094
• PEPT1- and OAT1/3-mediated Drug-drug Interactions Between Bestatin and Cefixime in Vivo and in Vitro in Rats, and in Vitro in Human
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Oct, 2014   |   Pubmed ID: 25016073
• OATP and MRP2-mediated Hepatic Uptake and Biliary Excretion of Eprosartan in Rat and Human
  Pharmacological Reports : PR. Apr, 2014   |   Pubmed ID: 24911086
• Dioscin Promotes Osteoblastic Proliferation and Differentiation Via Lrp5 and ER Pathway in Mouse and Human Osteoblast-like Cell Lines
  Journal of Biomedical Science. Apr, 2014   |   Pubmed ID: 24742230
• Aspirin and Probenecid Inhibit Organic Anion Transporter 3-mediated Renal Uptake of Cilostazol and Probenecid Induces Metabolism of Cilostazol in the Rat
  Drug Metabolism and Disposition: the Biological Fate of Chemicals. Jun, 2014   |   Pubmed ID: 24692216
• Dioscin Enhances Methotrexate Absorption by Down-regulating MDR1 in Vitro and in Vivo
  Toxicology and Applied Pharmacology. Jun, 2014   |   Pubmed ID: 24680847
• Luteolin Protects HUVECs from TNF-α-induced Oxidative Stress and Inflammation Via Its Effects on the Nox4/ROS-NF-κB and MAPK Pathways
  Journal of Atherosclerosis and Thrombosis. Month, 2014   |   Pubmed ID: 24621786
• Methotrexate-bestatin Interaction: Involvement of P-glycoprotein and Organic Anion Transporters in Rats
  International Journal of Pharmaceutics. Apr, 2014   |   Pubmed ID: 24530518
• Inhibitory Effect of Valsartan on the Intestinal Absorption and Renal Excretion of Bestatin in Rats
  Journal of Pharmaceutical Sciences. Feb, 2014   |   Pubmed ID: 24338900
• MDR1 and OAT1/OAT3 Mediate the Drug-drug Interaction Between Puerarin and Methotrexate
  Pharmaceutical Research. May, 2014   |   Pubmed ID: 24242937
• The Oligopeptide Transporter 2-mediated Reabsorption of Entecavir in Rat Kidney
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Feb, 2014   |   Pubmed ID: 24184752
• Enhancement Effect of P-gp Inhibitors on the Intestinal Absorption and Antiproliferative Activity of Bestatin
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Nov, 2013   |   Pubmed ID: 23981338
• Anti-cancer Effects of Dioscin on Three Kinds of Human Lung Cancer Cell Lines Through Inducing DNA Damage and Activating Mitochondrial Signal Pathway
  Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. Sep, 2013   |   Pubmed ID: 23764357
• Benzylpenicillin Inhibits the Renal Excretion of Acyclovir by OAT1 and OAT3
  Pharmacological Reports : PR. Month, 2013   |   Pubmed ID: 23744435
• JBP485 Improves Gentamicin-induced Acute Renal Failure by Regulating the Expression and Function of Oat1 and Oat3 in Rats
  Toxicology and Applied Pharmacology. May, 2013   |   Pubmed ID: 23707770
• Dioscin Restores the Activity of the Anticancer Agent Adriamycin in Multidrug-Resistant Human Leukemia K562/Adriamycin Cells by Down-Regulating MDR1 Via a Mechanism Involving NF-κB Signaling Inhibition
  Journal of Natural Products. May, 2013   |   Pubmed ID: 23621869
• Involvement of Organic Anion-transporting Polypeptides in the Hepatic Uptake of Dioscin in Rats and Humans
  Drug Metabolism and Disposition: the Biological Fate of Chemicals. May, 2013   |   Pubmed ID: 23396419
• OAT1 and OAT3: Targets of Drug-drug Interaction Between Entecavir and JBP485
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Mar, 2013   |   Pubmed ID: 23313623
• Inhibitory Effect of 1α,25-dihydroxyvitamin D₃ on Excretion of JBP485 Via Organic Anion Transporters in Rats
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Jan, 2013   |   Pubmed ID: 23201003
• Changes in Expression of Renal Oat1, Oat3 and Mrp2 in Cisplatin-induced Acute Renal Failure After Treatment of JBP485 in Rats
  Toxicology and Applied Pharmacology. Nov, 2012   |   Pubmed ID: 22992436
• Inhibitory Effect of JBP485 on Renal Excretion of Acyclovir by the Inhibition of OAT1 and OAT3
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Sep, 2012   |   Pubmed ID: 22728397
• Effect of JBP485 on Obstructive Jaundice is Related to Regulation of Renal Oat1, Oat3 and Mrp2 Expression in ANIT-treated Rats
  Peptides. Jul, 2012   |   Pubmed ID: 22521734
• Construction, Identification and Application of HeLa Cells Stably Transfected with Human PEPT1 and PEPT2
  Peptides. Apr, 2012   |   Pubmed ID: 22369721
• Organic Anion Transporters Involved in the Excretion of Bestatin in the Kidney
  Peptides. Feb, 2012   |   Pubmed ID: 22273603
• Subchronic Toxicity Study of the Total Flavonoids from Rosa Laevigata Michx Fruit in Rats
  Regulatory Toxicology and Pharmacology : RTP. Mar, 2012   |   Pubmed ID: 22226919
• Peptide Cotransporter 1 in Intestine and Organic Anion Transporters in Kidney Are Targets of Interaction Between JBP485 and Lisinopril in Rats
  Drug Metabolism and Pharmacokinetics. Month, 2012   |   Pubmed ID: 22123131
• Molecular Mechanisms of Biliary Excretion of Cefditoren and the Effects of Cefditoren on the Expression Levels of Hepatic Transporters
  Drug Metabolism and Pharmacokinetics. Month, 2010   |   Pubmed ID: 20814152
• Pharmacokinetic Interaction Between JBP485 and Cephalexin in Rats
  Drug Metabolism and Disposition: the Biological Fate of Chemicals. Jun, 2010   |   Pubmed ID: 20219852
• Laennec Protects Murine from Concanavalin A-induced Liver Injury Through Inhibition of Inflammatory Reactions and Hepatocyte Apoptosis
  Biological & Pharmaceutical Bulletin. Nov, 2008   |   Pubmed ID: 18981570
• Protective Effect of JBP485 on Concanavalin A-induced Hepatocyte Toxicity in Primary Cultured Rat Hepatocytes
  European Journal of Pharmacology. Jul, 2008   |   Pubmed ID: 18571156
• Increased Expression of Human Macrophage Metalloelastase (MMP-12) is Associated with the Invasion of Endometrial Adenocarcinoma
  Pathology, Research and Practice. Month, 2007   |   Pubmed ID: 17574772
• C-reactive Protein in Atherosclerotic Lesions: Its Origin and Pathophysiological Significance
  The American Journal of Pathology. Oct, 2005   |   Pubmed ID: 16192648
• Association of Increased Expression of Macrophage Elastase (matrix Metalloproteinase 12) with Rheumatoid Arthritis
  Arthritis and Rheumatism. Oct, 2004   |   Pubmed ID: 15476203
• Overexpression of Human Matrix Metalloproteinase-12 Enhances the Development of Inflammatory Arthritis in Transgenic Rabbits
  The American Journal of Pathology. Oct, 2004   |   Pubmed ID: 15466401