Manju M. Hingorani Molecular Biology and Biochemistry Department Wesleyan University Biography Publications Institution JoVE Articles Manju M. Hingorani has not added a biography. If you are Manju M. Hingorani and would like to personalize this page please email our Author Liaison for assistance. Publications ATP Binding and Hydrolysis-Driven Rate-Determining Events in the RFC-Catalyzed PCNA Clamp Loading Reaction Journal of Molecular Biology. Feb, 2012 | Pubmed ID: 22197378 A Central Swivel Point in the RFC Clamp Loader Controls PCNA Opening and Loading on DNA Journal of Molecular Biology. Feb, 2012 | Pubmed ID: 22197374 Dynamical Allosterism in the Mechanism of Action of DNA Mismatch Repair Protein MutS Biophysical Journal. Oct, 2011 | Pubmed ID: 21961599 Human MSH2 (hMSH2) Protein Controls ATP Processing by HMSH2-hMSH6 The Journal of Biological Chemistry. Nov, 2011 | Pubmed ID: 21937421 Saccharomyces Cerevisiae Msh2-Msh6 DNA Binding Kinetics Reveal a Mechanism of Targeting Sites for DNA Mismatch Repair Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 20080735 Model-based Global Analysis of Heterogeneous Experimental Data Using Gfit Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19399438 Mechanism of Cadmium-mediated Inhibition of Msh2-Msh6 Function in DNA Mismatch Repair Biochemistry. Oct, 2009 | Pubmed ID: 19320425 Mechanism of ATP-driven PCNA Clamp Loading by S. Cerevisiae RFC Journal of Molecular Biology. May, 2009 | Pubmed ID: 19285992 Structure of a Mutant Form of Proliferating Cell Nuclear Antigen That Blocks Translesion DNA Synthesis Biochemistry. Dec, 2008 | Pubmed ID: 19053247 Mechanism of MutS Searching for DNA Mismatches and Signaling Repair The Journal of Biological Chemistry. Dec, 2008 | Pubmed ID: 18854319 Conserved Residues in the Delta Subunit Help the E. Coli Clamp Loader, Gamma Complex, Target Primer-template DNA for Clamp Assembly Nucleic Acids Research. Jun, 2008 | Pubmed ID: 18424802 TIRF(ing) Reveals Msh2-Msh6 Surfing on DNA Nature Structural & Molecular Biology. Dec, 2007 | Pubmed ID: 18059451 The Effects of Nucleotides on MutS-DNA Binding Kinetics Clarify the Role of MutS ATPase Activity in Mismatch Repair Journal of Molecular Biology. Mar, 2007 | Pubmed ID: 17207499 Contribution of Msh2 and Msh6 Subunits to the Asymmetric ATPase and DNA Mismatch Binding Activities of Saccharomyces Cerevisiae Msh2-Msh6 Mismatch Repair Protein DNA Repair. Feb, 2006 | Pubmed ID: 16214425 Role of a Conserved Glutamate Residue in the Escherichia Coli SecA ATPase Mechanism The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15710614 Asymmetric ATP Binding and Hydrolysis Activity of the Thermus Aquaticus MutS Dimer is Key to Modulation of Its Interactions with Mismatched DNA Biochemistry. Oct, 2004 | Pubmed ID: 15476405 Dual Functions, Clamp Opening and Primer-template Recognition, Define a Key Clamp Loader Subunit Journal of Molecular Biology. Oct, 2004 | Pubmed ID: 15364574 Replication Factor C Clamp Loader Subunit Arrangement Within the Circular Pentamer and Its Attachment Points to Proliferating Cell Nuclear Antigen The Journal of Biological Chemistry. Dec, 2003 | Pubmed ID: 14530260 Overproduction and Analysis of Eukaryotic Multiprotein Complexes in Escherichia Coli Using a Dual-vector Strategy Analytical Biochemistry. Aug, 2003 | Pubmed ID: 12842110 Mismatch Recognition-coupled Stabilization of Msh2-Msh6 in an ATP-bound State at the Initiation of DNA Repair Biochemistry. Jul, 2003 | Pubmed ID: 12820877 Mechanism of Loading the Escherichia Coli DNA Polymerase III Beta Sliding Clamp on DNA. Bona Fide Primer/templates Preferentially Trigger the Gamma Complex to Hydrolyze ATP and Load the Clamp The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12519754 On the Specificity of Interaction Between the Saccharomyces Cerevisiae Clamp Loader Replication Factor C and Primed DNA Templates During DNA Replication The Journal of Biological Chemistry. Dec, 2002 | Pubmed ID: 12370190 Application of Stopped-flow Kinetics Methods to Investigate the Mechanism of Action of a DNA Repair Protein F. Noah Biro1, Jie Zhai1, Christopher W. Doucette1, Manju M. Hingorani1 1Molecular Biology and Biochemistry Department, Wesleyan University JoVE 1874 Biology
Application of Stopped-flow Kinetics Methods to Investigate the Mechanism of Action of a DNA Repair Protein F. Noah Biro1, Jie Zhai1, Christopher W. Doucette1, Manju M. Hingorani1 1Molecular Biology and Biochemistry Department, Wesleyan University JoVE 1874 Biology