My N. Helms Department of Internal Medicine, Pulmonary Division University of Utah Biography Publications Institution JoVE Articles My N. Helms has not added a biography. If you are My N. Helms and would like to personalize this page please email our Author Liaison for assistance. Publications Cysteine Oxidation Impairs Systemic Glucocorticoid Responsiveness in Children with Difficult-to-treat Asthma The Journal of Allergy and Clinical Immunology. Aug, 2015 | Pubmed ID: 25748343 Oxidized Glutathione (GSSG) Inhibits Epithelial Sodium Channel Activity in Primary Alveolar Epithelial Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. May, 2015 | Pubmed ID: 25713321 Receptor for Advanced Glycation End-products Regulates Lung Fluid Balance Via Protein Kinase C-gp91(phox) Signaling to Epithelial Sodium Channels American Journal of Respiratory Cell and Molecular Biology. Jan, 2015 | Pubmed ID: 24978055 ERp29, a Chaperone Protein Ushering in New Insights on Ion Transport Regulation. Focus on "ERp29 Regulates Epithelial Sodium Channel Functional Expression by Promoting Channel Cleavage" American Journal of Physiology. Cell Physiology. Oct, 2014 | Pubmed ID: 25009112 Chronic Ethanol Exposure Alters the Lung Proteome and Leads to Mitochondrial Dysfunction in Alveolar Type 2 Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Jun, 2014 | Pubmed ID: 24682449 Preclinical Anatomical, Molecular, and Functional Imaging of the Lung with Multiple Modalities American Journal of Physiology. Lung Cellular and Molecular Physiology. May, 2014 | Pubmed ID: 24658139 Hyperoxia Induces Alveolar Epithelial-to-mesenchymal Cell Transition American Journal of Physiology. Lung Cellular and Molecular Physiology. Feb, 2014 | Pubmed ID: 24375795 Regulation of Ion Transport by Oxidants American Journal of Physiology. Lung Cellular and Molecular Physiology. Nov, 2013 | Pubmed ID: 24014684 Fulvene-5 Inhibition of Nadph Oxidases Attenuates Activation of Epithelial Sodium Channels in A6 Distal Nephron Cells American Journal of Physiology. Renal Physiology. Oct, 2013 | Pubmed ID: 23863470 Acute Effects of Cigarette Smoke Extract on Alveolar Epithelial Sodium Channel Activity and Lung Fluid Clearance American Journal of Respiratory Cell and Molecular Biology. Aug, 2013 | Pubmed ID: 23526224 Chronic Alcohol Ingestion Changes the Landscape of the Alveolar Epithelium BioMed Research International. 2013 | Pubmed ID: 23509726 Ethanol Alters Alveolar Fluid Balance Via Nadph Oxidase (NOX) Signaling to Epithelial Sodium Channels (ENaC) in the Lung PloS One. 2013 | Pubmed ID: 23382956 H2O2 Regulates Lung Epithelial Sodium Channel (ENaC) Via Ubiquitin-like Protein Nedd8 The Journal of Biological Chemistry. Mar, 2013 | Pubmed ID: 23362276 Cholinergic Regulation of Epithelial Sodium Channels in Rat Alveolar Type 2 Epithelial Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Mar, 2013 | Pubmed ID: 23292809 β-Adrenergic Agonists Differentially Regulate Highly Selective and Nonselective Epithelial Sodium Channels to Promote Alveolar Fluid Clearance in Vivo American Journal of Physiology. Lung Cellular and Molecular Physiology. Jun, 2012 | Pubmed ID: 22505670 Nadph Oxidase Regulates Alveolar Epithelial Sodium Channel Activity and Lung Fluid Balance in Vivo Via OFormula Signaling American Journal of Physiology. Lung Cellular and Molecular Physiology. Feb, 2012 | Pubmed ID: 22160304 Epithelial Sodium Channel Regulation by Cell Surface-associated Serum- and Glucocorticoid-regulated Kinase 1 The Journal of Biological Chemistry. Sep, 2011 | Pubmed ID: 21784856 Loss of Desmocollin-2 Confers a Tumorigenic Phenotype to Colonic Epithelial Cells Through Activation of Akt/β-catenin Signaling Molecular Biology of the Cell. Apr, 2011 | Pubmed ID: 21325624 Rac1-mediated NADPH Oxidase Release of O2- Regulates Epithelial Sodium Channel Activity in the Alveolar Epithelium American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2010 | Pubmed ID: 20097736 Extracellular Matrix Influences Alveolar Epithelial Claudin Expression and Barrier Function American Journal of Respiratory Cell and Molecular Biology. Feb, 2010 | Pubmed ID: 19423774 The Contribution of Epithelial Sodium Channels to Alveolar Function in Health and Disease Annual Review of Physiology. 2009 | Pubmed ID: 18831683 Single-channel Analysis of Functional Epithelial Sodium Channel (ENaC) Stability at the Apical Membrane of A6 Distal Kidney Cells American Journal of Physiology. Renal Physiology. Nov, 2008 | Pubmed ID: 18784262 Redox Regulation of Epithelial Sodium Channels Examined in Alveolar Type 1 and 2 Cells Patch-clamped in Lung Slice Tissue The Journal of Biological Chemistry. Aug, 2008 | Pubmed ID: 18541535 Aldosterone-induced Increases in Superoxide Production Counters Nitric Oxide Inhibition of Epithelial Na Channel Activity in A6 Distal Nephron Cells American Journal of Physiology. Renal Physiology. Nov, 2007 | Pubmed ID: 17804482 Effect of Divalent Heavy Metals on Epithelial Na+ Channels in A6 Cells American Journal of Physiology. Renal Physiology. Jul, 2007 | Pubmed ID: 17429036 Dopamine Activates Amiloride-sensitive Sodium Channels in Alveolar Type I Cells in Lung Slice Preparations American Journal of Physiology. Lung Cellular and Molecular Physiology. Oct, 2006 | Pubmed ID: 16679376 Functional Ion Channels in Pulmonary Alveolar Type I Cells Support a Role for Type I Cells in Lung Ion Transport Proceedings of the National Academy of Sciences of the United States of America. Mar, 2006 | Pubmed ID: 16549766 Dopamine Regulation of Amiloride-sensitive Sodium Channels in Lung Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2006 | Pubmed ID: 16284210 Phosphatidylinositol 3,4,5-trisphosphate Mediates Aldosterone Stimulation of Epithelial Sodium Channel (ENaC) and Interacts with Gamma-ENaC The Journal of Biological Chemistry. Dec, 2005 | Pubmed ID: 16204229 Role of SGK1 in Nitric Oxide Inhibition of ENaC in Na+-transporting Epithelia American Journal of Physiology. Cell Physiology. Sep, 2005 | Pubmed ID: 15843443 Regulation of Sodium Transport in Mammalian Collecting Duct Cells by Aldosterone-induced Kinase, SGK1: Structure/function Studies Molecular and Cellular Endocrinology. Mar, 2004 | Pubmed ID: 15134818 Hormone-regulated Transepithelial Na+ Transport in Mammalian CCD Cells Requires SGK1 Expression American Journal of Physiology. Renal Physiology. Mar, 2003 | Pubmed ID: 12429555 Real-time X-ray Imaging van Lung Fluid Volumes in Neonatale Mouse Lung Ashley E. Van Avermaete1, Phi T. Trac1, Theresa W. Gauthier1, My N. Helms2 1Department of Pediatrics, Neonatology Division, Emory Children's Center, Emory University, 2Department of Internal Medicine, Pulmonary Division, University of Utah Medicine Directe Tracheale Instillatie van opgeloste stoffen in de muis Lung My N. Helms1,2, Edilson Torres-Gonzalez2,3, Preston Goodson1, Mauricio Rojas2,3 1Department of Physiology, Emory University, 2Center for Respiratory Health, Emory University, 3Department of Medicine, Emory University JoVE 1941 Biology
Real-time X-ray Imaging van Lung Fluid Volumes in Neonatale Mouse Lung Ashley E. Van Avermaete1, Phi T. Trac1, Theresa W. Gauthier1, My N. Helms2 1Department of Pediatrics, Neonatology Division, Emory Children's Center, Emory University, 2Department of Internal Medicine, Pulmonary Division, University of Utah Medicine
Directe Tracheale Instillatie van opgeloste stoffen in de muis Lung My N. Helms1,2, Edilson Torres-Gonzalez2,3, Preston Goodson1, Mauricio Rojas2,3 1Department of Physiology, Emory University, 2Center for Respiratory Health, Emory University, 3Department of Medicine, Emory University JoVE 1941 Biology