Norma Andrews Department of Cell Biology and Molecular Genetics University of Maryland Biography Publications Institution JoVE Articles Norma Andrews has not added a biography. If you are Norma Andrews and would like to personalize this page please email our Author Liaison for assistance. Publications Pathways of Iron Acquisition and Utilization in Leishmania Current Opinion in Microbiology. Aug, 2013 | Pubmed ID: 23962817 Irony of Fate: Role of Iron-mediated ROS in Leishmania Differentiation Trends in Parasitology. Aug, 2013 | Pubmed ID: 23948431 Heme Uptake Mediated by LHR1 is Essential for Leishmania Amazonensis Virulence Infection and Immunity. Jul, 2013 | Pubmed ID: 23876801 Iron Uptake Controls the Generation of Leishmania Infective Forms Through Regulation of ROS Levels The Journal of Experimental Medicine. Feb, 2013 | Pubmed ID: 23382545 Extracellular Amastigotes of Trypanosoma Cruzi Are Potent Inducers of Phagocytosis in Mammalian Cells Cellular Microbiology. Jun, 2013 | Pubmed ID: 23241026 Heme Uptake by Leishmania Amazonensis is Mediated by the Transmembrane Protein LHR1 PLoS Pathogens. 2012 | Pubmed ID: 22807677 Oxidative Stress and Intracellular Infections: More Iron to the Fire The Journal of Clinical Investigation. Jul, 2012 | Pubmed ID: 22728929 Host Cell Invasion by Trypanosoma Cruzi: a Unique Strategy That Promotes Persistence FEMS Microbiology Reviews. May, 2012 | Pubmed ID: 22339763 Toxin Pores Endocytosed During Plasma Membrane Repair Traffic into the Lumen of MVBs for Degradation Traffic (Copenhagen, Denmark). Mar, 2012 | Pubmed ID: 22212686 Trypanosoma Cruzi Trypomastigotes Induce Cytoskeleton Modifications During HeLa Cell Invasion Memórias Do Instituto Oswaldo Cruz. Dec, 2011 | Pubmed ID: 22241126 Leishmania Promotes Its Own Virulence by Inducing Expression of the Host Immune Inhibitory Ligand CD200 Cell Host & Microbe. Jun, 2011 | Pubmed ID: 21669395 LFR1 Ferric Iron Reductase of Leishmania Amazonensis is Essential for the Generation of Infective Parasite Forms The Journal of Biological Chemistry. Jul, 2011 | Pubmed ID: 21558274 Trypanosoma Cruzi Subverts the Sphingomyelinase-mediated Plasma Membrane Repair Pathway for Cell Invasion The Journal of Experimental Medicine. May, 2011 | Pubmed ID: 21536739 Palmitoylation-dependent Association with CD63 Targets the Ca2+ Sensor Synaptotagmin VII to Lysosomes The Journal of Cell Biology. Nov, 2010 | Pubmed ID: 21041449 Exocytosis of Acid Sphingomyelinase by Wounded Cells Promotes Endocytosis and Plasma Membrane Repair The Journal of Cell Biology. Jun, 2010 | Pubmed ID: 20530211 Synaptotagmin-mediated Vesicle Fusion Regulates Cell Migration Nature Immunology. Jun, 2010 | Pubmed ID: 20473299 Functional Characterization of LIT1, the Leishmania Amazonensis Ferrous Iron Transporter Molecular and Biochemical Parasitology. Mar, 2010 | Pubmed ID: 20025906 How Do Bone Cells Secrete Proteins? Advances in Experimental Medicine and Biology. 2010 | Pubmed ID: 19950020 Characterization of a 21kDa Protein from Trypanosoma Cruzi Associated with Mammalian Cell Invasion Microbes and Infection / Institut Pasteur. Apr, 2009 | Pubmed ID: 19344784 Differential Role of the Ca(2+) Sensor Synaptotagmin VII in Macrophages and Dendritic Cells Immunobiology. Jul, 2009 | Pubmed ID: 19157638 Control of Parasitophorous Vacuole Expansion by LYST/Beige Restricts the Intracellular Growth of Leishmania Amazonensis PLoS Pathogens. Oct, 2008 | Pubmed ID: 18927622 Two-way Traffic on the Road to Plasma Membrane Repair Trends in Cell Biology. Nov, 2008 | Pubmed ID: 18848451 Synaptotagmin VII Regulates Bone Remodeling by Modulating Osteoclast and Osteoblast Secretion Developmental Cell. Jun, 2008 | Pubmed ID: 18539119 Repair of Injured Plasma Membrane by Rapid Ca2+-dependent Endocytosis The Journal of Cell Biology. Mar, 2008 | Pubmed ID: 18316410 Iron Acquisition Within Host Cells and the Pathogenicity of Leishmania Cellular Microbiology. Feb, 2008 | Pubmed ID: 18070118 Regulation of Insulin Secretion and GLUT4 Trafficking by the Calcium Sensor Synaptotagmin VII Biochemical and Biophysical Research Communications. Oct, 2007 | Pubmed ID: 17720139 Expression and Function of Synaptotagmin VII in CTLs Journal of Immunology (Baltimore, Md. : 1950). Feb, 2007 | Pubmed ID: 17237398 A Leishmania Amazonensis ZIP Family Iron Transporter is Essential for Parasite Replication Within Macrophage Phagolysosomes The Journal of Experimental Medicine. Oct, 2006 | Pubmed ID: 17000865 Ca2+ and Synaptotagmin VII-dependent Delivery of Lysosomal Membrane to Nascent Phagosomes The Journal of Cell Biology. Sep, 2006 | Pubmed ID: 16982801 A Role for Synaptotagmin VII-regulated Exocytosis of Lysosomes in Neurite Outgrowth from Primary Sympathetic Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2006 | Pubmed ID: 16641243 The Trypanosoma Cruzi-host-cell Interplay: Location, Invasion, Retention Nature Reviews. Microbiology. Oct, 2005 | Pubmed ID: 16175174 There's More to Life Than Neurotransmission: the Regulation of Exocytosis by Synaptotagmin VII Trends in Cell Biology. Nov, 2005 | Pubmed ID: 16168654 Membrane Repair and Immunological Danger EMBO Reports. Sep, 2005 | Pubmed ID: 16138093 The Small Chemical Vacuolin-1 Alters the Morphology of Lysosomes Without Inhibiting Ca2+-regulated Exocytosis EMBO Reports. Sep, 2005 | Pubmed ID: 16113649 Membrane Resealing: Synaptotagmin VII Keeps Running the Show Science's STKE : Signal Transduction Knowledge Environment. May, 2005 | Pubmed ID: 15870423 Trypanosoma Cruzi Invades Synaptotagmin VII-deficient Cells by a PI-3 Kinase Independent Pathway Molecular and Biochemical Parasitology. May, 2005 | Pubmed ID: 15811535 Identification of the Reactive Cysteine Residues in Oligopeptidase B from Trypanosoma Brucei FEBS Letters. Apr, 2005 | Pubmed ID: 15811340 Defective Lysosomal Exocytosis and Plasma Membrane Repair in Chediak-Higashi/beige Cells Proceedings of the National Academy of Sciences of the United States of America. Nov, 2004 | Pubmed ID: 15557559 Lysosomal Fusion is Essential for the Retention of Trypanosoma Cruzi Inside Host Cells The Journal of Experimental Medicine. Nov, 2004 | Pubmed ID: 15520245 Synaptotagmin VII Restricts Fusion Pore Expansion During Lysosomal Exocytosis PLoS Biology. Aug, 2004 | Pubmed ID: 15226824 A Process for Controlling Intracellular Bacterial Infections Induced by Membrane Injury Science (New York, N.Y.). Jun, 2004 | Pubmed ID: 15178804 Identification of SNAREs Involved in Synaptotagmin VII-regulated Lysosomal Exocytosis The Journal of Biological Chemistry. May, 2004 | Pubmed ID: 14993220 Leishmania Amazonensis Rab7 Promotes Toxicity of the Amino Acid Ester Leu-OMe in Amastigote Megasomes Molecular and Biochemical Parasitology. Dec, 2003 | Pubmed ID: 14599671 Impaired Membrane Resealing and Autoimmune Myositis in Synaptotagmin VII-deficient Mice The Journal of Cell Biology. Aug, 2003 | Pubmed ID: 12925704 Subsite Specificity (S3, S2, S1', S2' and S3') of Oligopeptidase B from Trypanosoma Cruzi and Trypanosoma Brucei Using Fluorescent Quenched Peptides: Comparative Study and Identification of Specific Carboxypeptidase Activity The Biochemical Journal. Aug, 2003 | Pubmed ID: 12737623 Membrane Proximal Lysosomes Are the Major Vesicles Responsible for Calcium-dependent Exocytosis in Nonsecretory Cells The Journal of Cell Biology. Nov, 2002 | Pubmed ID: 12438417 Don't Bother to Knock--the Cell Invasion Strategy of Trypanosoma Cruzi Trends in Parasitology. Oct, 2002 | Pubmed ID: 12377585 Lysosomes and the Plasma Membrane: Trypanosomes Reveal a Secret Relationship The Journal of Cell Biology. Aug, 2002 | Pubmed ID: 12147679 Substrate Recognition Properties of Oligopeptidase B from Salmonella Enterica Serovar Typhimurium Journal of Bacteriology. Jun, 2002 | Pubmed ID: 12029050 Role for Sialic Acid in the Formation of Tight Lysosome-derived Vacuoles During Trypanosoma Cruzi Invasion Molecular and Biochemical Parasitology. Jan, 2002 | Pubmed ID: 11755197 Live Imaging Assay for Assessing the Roles of Ca2+ and Sphingomyelinase in the Repair of Pore-forming Toxin Wounds Christina Tam1, Andrew R. Flannery1, Norma Andrews1 1Department of Cell Biology and Molecular Genetics, University of Maryland JoVE 50531 Biology
Live Imaging Assay for Assessing the Roles of Ca2+ and Sphingomyelinase in the Repair of Pore-forming Toxin Wounds Christina Tam1, Andrew R. Flannery1, Norma Andrews1 1Department of Cell Biology and Molecular Genetics, University of Maryland JoVE 50531 Biology