Patrick Thompson Department of Biomedical and Molecular Sciences Queen's University Biography Publications Institution JoVE Articles Patrick Thompson has not added a biography. If you are Patrick Thompson and would like to personalize this page please email our Author Liaison for assistance. Publications Systemic Gene Transfer of a Hexosaminidase Variant Using an ScAAV9.47 Vector Corrects GM2 Gangliosidosis in Sandhoff Mice Human Gene Therapy. Jul, 2016 | Pubmed ID: 27199088 Novel Vector Design and Hexosaminidase Variant Enabling Self-Complementary Adeno-Associated Virus for the Treatment of Tay-Sachs Disease Human Gene Therapy. Jul, 2016 | Pubmed ID: 27197548 Construction of a Hybrid β-hexosaminidase Subunit Capable of Forming Stable Homodimers That Hydrolyze GM2 Ganglioside in Vivo Molecular Therapy. Methods & Clinical Development. 2016 | Pubmed ID: 26966698 Retrovirus-Mediated Expression of E2A-PBX1 Blocks Lymphoid Fate but Permits Retention of Myeloid Potential in Early Hematopoietic Progenitors PloS One. 2015 | Pubmed ID: 26098938 Structural Basis of CBP/p300 Recruitment in Leukemia Induction by E2A-PBX1 Blood. Nov, 2012 | Pubmed ID: 22972988 E2A Proteins Enhance the Histone Acetyltransferase Activity of the Transcriptional Co-activators CBP and P300 Biochimica Et Biophysica Acta. May, 2012 | Pubmed ID: 22387215 Mapping Acetylation Sites in E2A Identifies a Conserved Lysine Residue in Activation Domain 1 That Promotes CBP/p300 Recruitment and Transcriptional Activation Biochimica Et Biophysica Acta. May, 2012 | Pubmed ID: 22207202 Anti-CD3 Prevents Factor VIII Inhibitor Development in Hemophilia A Mice by a Regulatory CD4+CD25+-dependent Mechanism and by Shifting Cytokine Production to Favor a Th1 Response Blood. Jan, 2009 | Pubmed ID: 18815284 Battery of Behavioral Tests Assessing General Locomotion, Muscular Strength, and Coordination in Mice Karlaina JL Osmon1, Meera Vyas1, Evan Woodley2, Patrick Thompson2, Jagdeep S Walia1,2,3 1Centre for Neuroscience Studies, Queen's University, 2Department of Biomedical and Molecular Sciences, Queen's University, 3Medical Genetics/ Department of Pediatrics, Kingston General Hospital, Centre for Neuroscience Studies, and Department of Biomedical and Molecular Sciences, Queen's University JoVE 55491 Behavior
Battery of Behavioral Tests Assessing General Locomotion, Muscular Strength, and Coordination in Mice Karlaina JL Osmon1, Meera Vyas1, Evan Woodley2, Patrick Thompson2, Jagdeep S Walia1,2,3 1Centre for Neuroscience Studies, Queen's University, 2Department of Biomedical and Molecular Sciences, Queen's University, 3Medical Genetics/ Department of Pediatrics, Kingston General Hospital, Centre for Neuroscience Studies, and Department of Biomedical and Molecular Sciences, Queen's University JoVE 55491 Behavior
