Peter Setlow Department of Molecular Biology and Biophysics University of Connecticut Health Center Biography Publications Institution JoVE Articles Peter Setlow Dr. Peter Setlow is Distinguished Professor of Molecular Biology and Biophysics at UConn Health in Farmington, CT. He received a BA in Chemistry from Swarthmore College, and a PhD in Biochemistry from Brandeis University. After postdoctoral work in the Department of Biochemistry at Stanford University Medical School with the late Nobel Laureate Dr. Arthur Kornberg, he joined the faculty of the University of Connecticut Health Center (now UConn Health) in the Department of Biochemistry. His research interests are the formation, biochemistry, resistance, killing and germination of spores of the bacteria of Bacillus species, and he has published more than 500 articles on the biochemistry, physiology, resistance, killing and germination of spores of various Bacillus species. Dr. Setlow has been a Principal Investigator on grants from the NIH and the Department of Defense for more than 40 years. He is currently a member of the editorial boards of Journal of Bacteriology, Applied and Environmental Microbiology and the International Journal of Food Microbiology, and an editor of Journal of Applied Microbiology, Letters in Applied Microbiology and PLoS One. Dr. Setlow is a Fellow of the American Academy of Microbiology, an Honorary Member of the Society for Applied Microbiology in the United Kingdom, and a member of the Connecticut Academy of Science and Engineering. Dr. Setlow is also a member in the American Society for Microbiology, and the American Association for the Advancement of Science. Publications High Precision Fitting Measurements of the Kinetics of Size Changes During Germination of Individual Bacillus Spores Applied and Environmental Microbiology. May, 2014 | Pubmed ID: 24837375 Monitoring of Commitment, Blocking, and Continuation of Nutrient Germination of Individual Bacillus Subtilis Spores Journal of Bacteriology. Jul, 2014 | Pubmed ID: 24769693 Function of the SpoVAEa and SpoVAF Proteins of Bacillus Subtilis Spores Journal of Bacteriology. Jun, 2014 | Pubmed ID: 24682327 Analysis of the Loss in Heat and Acid Resistance During Germination of Spores of Bacillus Species Journal of Bacteriology. May, 2014 | Pubmed ID: 24563034 Structural and Functional Analysis of the GerD Spore Germination Protein of Bacillus Species Journal of Molecular Biology. May, 2014 | Pubmed ID: 24530795 Germination of Spores of Bacillus Species: What We Know and Do Not Know Journal of Bacteriology. Apr, 2014 | Pubmed ID: 24488313 High Salinity Alters the Germination Behavior of Bacillus Subtilis Spores with Nutrient and Nonnutrient Germinants Applied and Environmental Microbiology. Feb, 2014 | Pubmed ID: 24317076 Interaction of Apurinic/apyrimidinic Endonucleases Nfo and ExoA with the DNA Integrity Scanning Protein DisA in the Processing of Oxidative DNA Damage During Bacillus Subtilis Spore Outgrowth Journal of Bacteriology. Feb, 2014 | Pubmed ID: 24244006 Monitoring Rates and Heterogeneity of High-pressure Germination of Bacillus Spores by Phase-contrast Microscopy of Individual Spores Applied and Environmental Microbiology. Jan, 2014 | Pubmed ID: 24162576 Resistance of Bacillus Subtilis Spore DNA to Lethal Ionizing Radiation Damage Relies Primarily on Spore Core Components and DNA Repair, with Minor Effects of Oxygen Radical Detoxification Applied and Environmental Microbiology. Jan, 2014 | Pubmed ID: 24123749 Observation of the Dynamic Germination of Single Bacterial Spores Using Rapid Raman Imaging Journal of Biomedical Optics. Month, 2014 | Pubmed ID: 23843133 Mobility of Core Water in Bacillus Subtilis Spores by 2H NMR Biophysical Journal. Nov, 2013 | Pubmed ID: 24209846 Kinetics of Germination of Individual Spores of Geobacillus Stearothermophilus As Measured by Raman Spectroscopy and Differential Interference Contrast Microscopy PloS One. Month, 2013 | Pubmed ID: 24058645 The Clostridium Perfringens Germinant Receptor Protein GerKC is Located in the Spore Inner Membrane and is Crucial for Spore Germination Journal of Bacteriology. Nov, 2013 | Pubmed ID: 24013629 A Conserved ClpP-like Protease Involved in Spore Outgrowth in Bacillus Subtilis Molecular Microbiology. Oct, 2013 | Pubmed ID: 23927687 Direct Analysis of Water Content and Movement in Single Dormant Bacterial Spores Using Confocal Raman Microspectroscopy and Raman Imaging Analytical Chemistry. Aug, 2013 | Pubmed ID: 23815288 Numbers of Individual Nutrient Germinant Receptors and Other Germination Proteins in Spores of Bacillus Subtilis Journal of Bacteriology. Aug, 2013 | Pubmed ID: 23749970 A Novel RNA Polymerase-binding Protein Controlling Genes Involved in Spore Germination in Bacillus Subtilis Molecular Microbiology. Jul, 2013 | Pubmed ID: 23678950 Identification of New Proteins That Modulate the Germination of Spores of Bacillus Species Journal of Bacteriology. Jul, 2013 | Pubmed ID: 23625846 Activity and Regulation of Various Forms of CwlJ, SleB, and YpeB Proteins in Degrading Cortex Peptidoglycan of Spores of Bacillus Species in Vitro and During Spore Germination Journal of Bacteriology. Jun, 2013 | Pubmed ID: 23543708 Expression Level of Bacillus Subtilis Germinant Receptors Determines the Average Rate but Not the Heterogeneity of Spore Germination Journal of Bacteriology. Apr, 2013 | Pubmed ID: 23396907 Topology and Accessibility of Germination Proteins in the Bacillus Subtilis Spore Inner Membrane Journal of Bacteriology. Apr, 2013 | Pubmed ID: 23335419 Alternative Excision Repair of Ultraviolet B- and C-induced DNA Damage in Dormant and Developing Spores of Bacillus Subtilis Journal of Bacteriology. Nov, 2012 | Pubmed ID: 22961846 Analysis of the Effects of a GerP Mutation on the Germination of Spores of Bacillus Subtilis Journal of Bacteriology. Nov, 2012 | Pubmed ID: 22904285 Analysis of the Raman Spectra of Ca(2+)-dipicolinic Acid Alone and in the Bacterial Spore Core in Both Aqueous and Dehydrated Environments The Analyst. Aug, 2012 | Pubmed ID: 22763367 Crystal Structure of the Catalytic Domain of the Bacillus Cereus SleB Protein, Important in Cortex Peptidoglycan Degradation During Spore Germination Journal of Bacteriology. Sep, 2012 | Pubmed ID: 22730118 Effects of the SpoVT Regulatory Protein on the Germination and Germination Protein Levels of Spores of Bacillus Subtilis Journal of Bacteriology. Jul, 2012 | Pubmed ID: 22522895 Germination Protein Levels and Rates of Germination of Spores of Bacillus Subtilis with Overexpressed or Deleted Genes Encoding Germination Proteins Journal of Bacteriology. Jun, 2012 | Pubmed ID: 22493018 Levels of Germination Proteins in Dormant and Superdormant Spores of Bacillus Subtilis Journal of Bacteriology. May, 2012 | Pubmed ID: 22343299 Role of a SpoVA Protein in Dipicolinic Acid Uptake into Developing Spores of Bacillus Subtilis Journal of Bacteriology. Apr, 2012 | Pubmed ID: 22328679 Effects of Sporulation Conditions on the Germination and Germination Protein Levels of Bacillus Subtilis Spores Applied and Environmental Microbiology. Apr, 2012 | Pubmed ID: 22327596 Dynamics of the Assembly of a Complex Macromolecular Structure--the Coat of Spores of the Bacterium Bacillus Subtilis Molecular Microbiology. Jan, 2012 | Pubmed ID: 22192522 Effects of Cortex Peptidoglycan Structure and Cortex Hydrolysis on the Kinetics of Ca(2+)-dipicolinic Acid Release During Bacillus Subtilis Spore Germination Journal of Bacteriology. Feb, 2012 | Pubmed ID: 22123250 Roles of Endonuclease V, Uracil-DNA Glycosylase, and Mismatch Repair in Bacillus Subtilis DNA Base-deamination-induced Mutagenesis Journal of Bacteriology. Jan, 2012 | Pubmed ID: 22056936 Multifocus Confocal Raman Microspectroscopy for Rapid Single-particle Analysis Journal of Biomedical Optics. Dec, 2011 | Pubmed ID: 22191908 Maturation of Released Spores is Necessary for Acquisition of Full Spore Heat Resistance During Bacillus Subtilis Sporulation Applied and Environmental Microbiology. Oct, 2011 | Pubmed ID: 21821751 Synergism Between Different Germinant Receptors in the Germination of Bacillus Subtilis Spores Journal of Bacteriology. Sep, 2011 | Pubmed ID: 21725007 Germination Proteins in the Inner Membrane of Dormant Bacillus Subtilis Spores Colocalize in a Discrete Cluster Molecular Microbiology. Aug, 2011 | Pubmed ID: 21696470 Structure-based Functional Studies of the Effects of Amino Acid Substitutions in GerBC, the C Subunit of the Bacillus Subtilis GerB Spore Germinant Receptor Journal of Bacteriology. Aug, 2011 | Pubmed ID: 21685283 Efficient Inhibition of Germination of Coat-deficient Bacterial Spores by Multivalent Metal Cations, Including Terbium (Tb³+) Applied and Environmental Microbiology. Aug, 2011 | Pubmed ID: 21685163 Quantitative Analysis of Spatial-temporal Correlations During Germination of Spores of Bacillus Species Journal of Bacteriology. Aug, 2011 | Pubmed ID: 21622756 Monitoring the Wet-heat Inactivation Dynamics of Single Spores of Bacillus Species by Using Raman Tweezers, Differential Interference Contrast Microscopy, and Nucleic Acid Dye Fluorescence Microscopy Applied and Environmental Microbiology. Jul, 2011 | Pubmed ID: 21602365 Characterization of Bacterial Spore Germination Using Phase-contrast and Fluorescence Microscopy, Raman Spectroscopy and Optical Tweezers Nature Protocols. May, 2011 | Pubmed ID: 21527920 Role of the Nfo and ExoA Apurinic/apyrimidinic Endonucleases in Radiation Resistance and Radiation-induced Mutagenesis of Bacillus Subtilis Spores Journal of Bacteriology. Jun, 2011 | Pubmed ID: 21441501 Kinetics of Germination of Wet-heat-treated Individual Spores of Bacillus Species, Monitored by Raman Spectroscopy and Differential Interference Contrast Microscopy Applied and Environmental Microbiology. May, 2011 | Pubmed ID: 21441336 Germination of Individual Bacillus Subtilis Spores with Alterations in the GerD and SpoVA Proteins, Which Are Important in Spore Germination Journal of Bacteriology. May, 2011 | Pubmed ID: 21398556 Extremely Variable Conservation of γ-type Small, Acid-soluble Proteins from Spores of Some Species in the Bacterial Order Bacillales Journal of Bacteriology. Apr, 2011 | Pubmed ID: 21317325 Germination of Spores of Bacillales and Clostridiales Species: Mechanisms and Proteins Involved Trends in Microbiology. Feb, 2011 | Pubmed ID: 21112786 Effects of Mn and Fe Levels on Bacillus Subtilis Spore Resistance and Effects of Mn2+, Other Divalent Cations, Orthophosphate, and Dipicolinic Acid on Protein Resistance to Ionizing Radiation Applied and Environmental Microbiology. Jan, 2011 | Pubmed ID: 21057011 Combination of Raman Tweezers and Quantitative Differential Interference Contrast Microscopy for Measurement of Dynamics and Heterogeneity During the Germination of Individual Bacterial Spores Journal of Biomedical Optics. Sep-Oct, 2010 | Pubmed ID: 21054104 Multiple-trap Laser Tweezers Raman Spectroscopy for Simultaneous Monitoring of the Biological Dynamics of Multiple Individual Cells Optics Letters. Oct, 2010 | Pubmed ID: 20967053 Monitoring the Kinetics of Uptake of a Nucleic Acid Dye During the Germination of Single Spores of Bacillus Species Analytical Chemistry. Oct, 2010 | Pubmed ID: 20873796 Crystal Structure of the GerBC Component of a Bacillus Subtilis Spore Germinant Receptor Journal of Molecular Biology. Sep, 2010 | Pubmed ID: 20654628 Factors Affecting Variability in Time Between Addition of Nutrient Germinants and Rapid Dipicolinic Acid Release During Germination of Spores of Bacillus Species Journal of Bacteriology. Jul, 2010 | Pubmed ID: 20472791 Studies of the Commitment Step in the Germination of Spores of Bacillus Species Journal of Bacteriology. Jul, 2010 | Pubmed ID: 20435722 Characterization of Bacterial Spore Germination Using Integrated Phase Contrast Microscopy, Raman Spectroscopy, and Optical Tweezers Analytical Chemistry. May, 2010 | Pubmed ID: 20369827 Characterization of Wet-heat Inactivation of Single Spores of Bacillus Species by Dual-trap Raman Spectroscopy and Elastic Light Scattering Applied and Environmental Microbiology. Mar, 2010 | Pubmed ID: 20097820 Superdormant Spores of Bacillus Species Germinate Normally with High Pressure, Peptidoglycan Fragments, and Bryostatin Journal of Bacteriology. Mar, 2010 | Pubmed ID: 20047906 Effects of Forespore-specific Overexpression of Apurinic/apyrimidinic Endonuclease Nfo on the DNA-damage Resistance Properties of Bacillus Subtilis Spores FEMS Microbiology Letters. Jan, 2010 | Pubmed ID: 19930460 The Physical State of Water in Bacterial Spores Proceedings of the National Academy of Sciences of the United States of America. Nov, 2009 | Pubmed ID: 19892742 Structural and Genetic Analysis of X-ray Scattering by Spores of Bacillus Subtilis Journal of Bacteriology. Dec, 2009 | Pubmed ID: 19837800 Characterization of Single Heat-activated Bacillus Spores Using Laser Tweezers Raman Spectroscopy Optics Express. Sep, 2009 | Pubmed ID: 19770863 Workshop Report: Modeling the Molecular Mechanism of Bacterial Spore Germination and Elucidating Reasons for Germination Heterogeneity Journal of Food Science. Aug, 2009 | Pubmed ID: 19723224 The Protease CspB is Essential for Initiation of Cortex Hydrolysis and Dipicolinic Acid (DPA) Release During Germination of Spores of Clostridium Perfringens Type A Food Poisoning Isolates Microbiology (Reading, England). Oct, 2009 | Pubmed ID: 19628563 Superdormant Spores of Bacillus Species Have Elevated Wet-heat Resistance and Temperature Requirements for Heat Activation Journal of Bacteriology. Sep, 2009 | Pubmed ID: 19592590 Roles of Small, Acid-soluble Spore Proteins and Core Water Content in Survival of Bacillus Subtilis Spores Exposed to Environmental Solar UV Radiation Applied and Environmental Microbiology. Aug, 2009 | Pubmed ID: 19542328 Elastic and Inelastic Light Scattering from Single Bacterial Spores in an Optical Trap Allows the Monitoring of Spore Germination Dynamics Analytical Chemistry. May, 2009 | Pubmed ID: 19374431 GerO, a Putative Na+/H+-K+ Antiporter, is Essential for Normal Germination of Spores of the Pathogenic Bacterium Clostridium Perfringens Journal of Bacteriology. Jun, 2009 | Pubmed ID: 19363115 Role of GerKB in Germination and Outgrowth of Clostridium Perfringens Spores Applied and Environmental Microbiology. Jun, 2009 | Pubmed ID: 19363077 Levels and Localization of Mechanosensitive Channel Proteins in Bacillus Subtilis Archives of Microbiology. May, 2009 | Pubmed ID: 19252899 SleC is Essential for Cortex Peptidoglycan Hydrolysis During Germination of Spores of the Pathogenic Bacterium Clostridium Perfringens Journal of Bacteriology. Apr, 2009 | Pubmed ID: 19218389 Isolation and Characterization of Superdormant Spores of Bacillus Species Journal of Bacteriology. Mar, 2009 | Pubmed ID: 19136594 Dormant Spores Receive an Unexpected Wake-up Call Cell. Oct, 2008 | Pubmed ID: 18984151 Characterization of Spores of Bacillus Subtilis That Lack Most Coat Layers Journal of Bacteriology. Oct, 2008 | Pubmed ID: 18723620 Sampling and Quantitative Analysis of Clean B. Subtilis Spores at Sub-monolayer Coverage by Reflectance Fourier Transform Infrared Microscopy Using Gold-coated Filter Substrates Applied Spectroscopy. Aug, 2008 | Pubmed ID: 18702861 Protozoal Digestion of Coat-defective Bacillus Subtilis Spores Produces "rinds" Composed of Insoluble Coat Protein Applied and Environmental Microbiology. Oct, 2008 | Pubmed ID: 18689521 Germination of Spores of Clostridium Difficile Strains, Including Isolates from a Hospital Outbreak of Clostridium Difficile-associated Disease (CDAD) Microbiology (Reading, England). Aug, 2008 | Pubmed ID: 18667557 Localization of the Germination Protein GerD to the Inner Membrane in Bacillus Subtilis Spores Journal of Bacteriology. Aug, 2008 | Pubmed ID: 18556788 Release of Small Molecules During Germination of Spores of Bacillus Species Journal of Bacteriology. Jul, 2008 | Pubmed ID: 18469112 Characterization of Clostridium Perfringens Spores That Lack SpoVA Proteins and Dipicolinic Acid Journal of Bacteriology. Jul, 2008 | Pubmed ID: 18469104 Role of Dipicolinic Acid in the Germination, Stability, and Viability of Spores of Bacillus Subtilis Journal of Bacteriology. Jul, 2008 | Pubmed ID: 18469099 Roles of DacB and Spm Proteins in Clostridium Perfringens Spore Resistance to Moist Heat, Chemicals, and UV Radiation Applied and Environmental Microbiology. Jun, 2008 | Pubmed ID: 18441110 Structure of a Protein-DNA Complex Essential for DNA Protection in Spores of Bacillus Species Proceedings of the National Academy of Sciences of the United States of America. Feb, 2008 | Pubmed ID: 18287075 Role of the Nfo and ExoA Apurinic/apyrimidinic Endonucleases in Repair of DNA Damage During Outgrowth of Bacillus Subtilis Spores Journal of Bacteriology. Mar, 2008 | Pubmed ID: 18203828 Clostridium Perfringens Spore Germination: Characterization of Germinants and Their Receptors Journal of Bacteriology. Feb, 2008 | Pubmed ID: 18083820 Roles of the Major, Small, Acid-soluble Spore Proteins and Spore-specific and Universal DNA Repair Mechanisms in Resistance of Bacillus Subtilis Spores to Ionizing Radiation from X Rays and High-energy Charged-particle Bombardment Journal of Bacteriology. Feb, 2008 | Pubmed ID: 18055591 Characterization of Amorphous Solids with Weak Glass Transitions Using High Ramp Rate Differential Scanning Calorimetry Journal of Pharmaceutical Sciences. Feb, 2008 | Pubmed ID: 17724657 Growth, Osmotic Downshock Resistance and Differentiation of Bacillus Subtilis Strains Lacking Mechanosensitive Channels Archives of Microbiology. Jan, 2008 | Pubmed ID: 17665170 How Moist Heat Kills Spores of Bacillus Subtilis Journal of Bacteriology. Dec, 2007 | Pubmed ID: 17890306 Effect of a Small, Acid-soluble Spore Protein from Clostridium Perfringens on the Resistance Properties of Bacillus Subtilis Spores Journal of Bacteriology. Nov, 2007 | Pubmed ID: 17766414 Analysis of Interactions Between Nutrient Germinant Receptors and SpoVA Proteins of Bacillus Subtilis Spores FEMS Microbiology Letters. Sep, 2007 | Pubmed ID: 17573930 Structure, Flexibility, and Mechanism of the Bacillus Stearothermophilus RecU Holliday Junction Resolvase Proteins. Sep, 2007 | Pubmed ID: 17557334 Crystallization and Preliminary X-ray Analysis of the Complex Between a Bacillus Subtilis Alpha/beta-type Small Acid-soluble Spore Protein and DNA Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Jun, 2007 | Pubmed ID: 17554173 Levels of Ca2+-dipicolinic Acid in Individual Bacillus Spores Determined Using Microfluidic Raman Tweezers Journal of Bacteriology. Jul, 2007 | Pubmed ID: 17468248 I Will Survive: DNA Protection in Bacterial Spores Trends in Microbiology. Apr, 2007 | Pubmed ID: 17336071 Antisense-RNA-mediated Decreased Synthesis of Small, Acid-soluble Spore Proteins Leads to Decreased Resistance of Clostridium Perfringens Spores to Moist Heat and UV Radiation Applied and Environmental Microbiology. Apr, 2007 | Pubmed ID: 17259355 Role of SpoVA Proteins in Release of Dipicolinic Acid During Germination of Bacillus Subtilis Spores Triggered by Dodecylamine or Lysozyme Journal of Bacteriology. Mar, 2007 | Pubmed ID: 17158659 Role of GerD in Germination of Bacillus Subtilis Spores Journal of Bacteriology. Feb, 2007 | Pubmed ID: 17122337 Structure and Molecular Mechanism of Bacillus Anthracis Cofactor-independent Phosphoglycerate Mutase: a Crucial Enzyme for Spores and Growing Cells of Bacillus Species Biophysical Journal. Feb, 2007 | Pubmed ID: 17085493 Localization of the Transglutaminase Cross-linking Sites in the Bacillus Subtilis Spore Coat Protein GerQ Journal of Bacteriology. Nov, 2006 | Pubmed ID: 16936016 The Synthesis and Role of the Mechanosensitive Channel of Large Conductance in Growth and Differentiation of Bacillus Subtilis Archives of Microbiology. Nov, 2006 | Pubmed ID: 16897034 Investigating the Role of Small, Acid-soluble Spore Proteins (SASPs) in the Resistance of Clostridium Perfringens Spores to Heat BMC Microbiology. Month, 2006 | Pubmed ID: 16759397 Transcription of the Bacillus Subtilis GerK Operon, Which Encodes a Spore Germinant Receptor, and Comparison with That of Operons Encoding Other Germinant Receptors Journal of Bacteriology. Jun, 2006 | Pubmed ID: 16707705 Role of Dipicolinic Acid in Resistance and Stability of Spores of Bacillus Subtilis with or Without DNA-protective Alpha/beta-type Small Acid-soluble Proteins Journal of Bacteriology. Jun, 2006 | Pubmed ID: 16707666 Levels of Glycine Betaine in Growing Cells and Spores of Bacillus Species and Lack of Effect of Glycine Betaine on Dormant Spore Resistance Journal of Bacteriology. Apr, 2006 | Pubmed ID: 16585779 YtkD and MutT Protect Vegetative Cells but Not Spores of Bacillus Subtilis from Oxidative Stress Journal of Bacteriology. Mar, 2006 | Pubmed ID: 16513759 The Forespore Line of Gene Expression in Bacillus Subtilis Journal of Molecular Biology. Apr, 2006 | Pubmed ID: 16497325 The Bacillus Subtilis Spore Coat Provides "eat Resistance" During Phagocytic Predation by the Protozoan Tetrahymena Thermophila Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006 | Pubmed ID: 16371471 Cooperativity Between Different Nutrient Receptors in Germination of Spores of Bacillus Subtilis and Reduction of This Cooperativity by Alterations in the GerB Receptor Journal of Bacteriology. Jan, 2006 | Pubmed ID: 16352818 Role of the Nfo (YqfS) and ExoA Apurinic/apyrimidinic Endonucleases in Protecting Bacillus Subtilis Spores from DNA Damage Journal of Bacteriology. Nov, 2005 | Pubmed ID: 16237020 Factors Influencing Germination of Bacillus Subtilis Spores Via Activation of Nutrient Receptors by High Pressure Applied and Environmental Microbiology. Oct, 2005 | Pubmed ID: 16204500 Site-directed Mutagenesis and Structural Studies Suggest That the Germination Protease, GPR, in Spores of Bacillus Species is an Atypical Aspartic Acid Protease Journal of Bacteriology. Oct, 2005 | Pubmed ID: 16199582 Localization of SpoVAD to the Inner Membrane of Spores of Bacillus Subtilis Journal of Bacteriology. Aug, 2005 | Pubmed ID: 16077113 Photosensitization of DNA by Dipicolinic Acid, a Major Component of Spores of Bacillus Species Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology. Aug, 2005 | Pubmed ID: 16052264 Interaction Between Individual Protein Components of the GerA and GerB Nutrient Receptors That Trigger Germination of Bacillus Subtilis Spores Journal of Bacteriology. Apr, 2005 | Pubmed ID: 15774895 The Solar UV Environment and Bacterial Spore UV Resistance: Considerations for Earth-to-Mars Transport by Natural Processes and Human Spaceflight Mutation Research. Apr, 2005 | Pubmed ID: 15748651 Effects of the Binding of Alpha/beta-type Small, Acid-soluble Spore Proteins on the Photochemistry of DNA in Spores of Bacillus Subtilis and in Vitro Photochemistry and Photobiology. Jan-Feb, 2005 | Pubmed ID: 15458366 Analysis of the Germination of Spores of Bacillus Subtilis with Temperature Sensitive Spo Mutations in the SpoVA Operon FEMS Microbiology Letters. Oct, 2004 | Pubmed ID: 15451103 Transglutaminase-mediated Cross-linking of GerQ in the Coats of Bacillus Subtilis Spores Journal of Bacteriology. Sep, 2004 | Pubmed ID: 15317760 Differential Gene Expression to Investigate the Effect of (5Z)-4-bromo- 5-(bromomethylene)-3-butyl-2(5H)-furanone on Bacillus Subtilis Applied and Environmental Microbiology. Aug, 2004 | Pubmed ID: 15294834 Structure of the DNA-SspC Complex: Implications for DNA Packaging, Protection, and Repair in Bacterial Spores Journal of Bacteriology. Jun, 2004 | Pubmed ID: 15150240 Lipids in the Inner Membrane of Dormant Spores of Bacillus Species Are Largely Immobile Proceedings of the National Academy of Sciences of the United States of America. May, 2004 | Pubmed ID: 15126669 Effects of a GerF (lgt) Mutation on the Germination of Spores of Bacillus Subtilis Journal of Bacteriology. May, 2004 | Pubmed ID: 15126458 Gene Expression in Bacillus Subtilis Surface Biofilms with and Without Sporulation and the Importance of YveR for Biofilm Maintenance Biotechnology and Bioengineering. May, 2004 | Pubmed ID: 15083514 Killing of Bacillus Subtilis Spores by a Modified Fenton Reagent Containing CuCl2 and Ascorbic Acid Applied and Environmental Microbiology. Apr, 2004 | Pubmed ID: 15066856 Identification of Aryl-phospho-beta-D-glucosidases in Bacillus Subtilis Archives of Microbiology. Jan, 2004 | Pubmed ID: 14652714 Spore Germination Current Opinion in Microbiology. Dec, 2003 | Pubmed ID: 14662349 Effects of Carboxy-terminal Modifications and PH on Binding of a Bacillus Subtilis Small, Acid-soluble Spore Protein to DNA Journal of Bacteriology. Oct, 2003 | Pubmed ID: 14526021 Effects of Overexpression of Nutrient Receptors on Germination of Spores of Bacillus Subtilis Journal of Bacteriology. Apr, 2003 | Pubmed ID: 12670969 A Soluble Protein is Immobile in Dormant Spores of Bacillus Subtilis but is Mobile in Germinated Spores: Implications for Spore Dormancy Proceedings of the National Academy of Sciences of the United States of America. Apr, 2003 | Pubmed ID: 12646705 Identification of a New Gene Essential for Germination of Bacillus Subtilis Spores with Ca2+-dipicolinate Journal of Bacteriology. Apr, 2003 | Pubmed ID: 12644503 Small, Acid-soluble Proteins As Biomarkers in Mass Spectrometry Analysis of Bacillus Spores Applied and Environmental Microbiology. Feb, 2003 | Pubmed ID: 12571035 UV Photochemistry of DNA in Vitro and in Bacillus Subtilis Spores at Earth-ambient and Low Atmospheric Pressure: Implications for Spore Survival on Other Planets or Moons in the Solar System Astrobiology. Month, 2002 | Pubmed ID: 12593780 PrfA Protein of Bacillus Species: Prediction and Demonstration of Endonuclease Activity on DNA Protein Science : a Publication of the Protein Society. Oct, 2002 | Pubmed ID: 12237459 Protection of DNA by Alpha/beta-type Small, Acid-soluble Proteins from Bacillus Subtilis Spores Against Cytosine Deamination Biochemistry. Sep, 2002 | Pubmed ID: 12234173 Base-change Mutations Induced by Various Treatments of Bacillus Subtilis Spores with and Without DNA Protective Small, Acid-soluble Spore Proteins Mutation Research. Jun, 2002 | Pubmed ID: 12052506 Mechanisms of Induction of Germination of Bacillus Subtilis Spores by High Pressure Applied and Environmental Microbiology. Jun, 2002 | Pubmed ID: 12039788 Structure and Mechanism of Action of a Cofactor-dependent Phosphoglycerate Mutase Homolog from Bacillus Stearothermophilus with Broad Specificity Phosphatase Activity Journal of Molecular Biology. Feb, 2002 | Pubmed ID: 11827481 Localization of the Cortex Lytic Enzyme CwlJ in Spores of Bacillus Subtilis Journal of Bacteriology. Feb, 2002 | Pubmed ID: 11807087 Killing of Spores of Bacillus Subtilis by Peroxynitrite Appears to Be Caused by Membrane Damage Microbiology (Reading, England). Jan, 2002 | Pubmed ID: 11782523 The Products of the SpoVA Operon Are Involved in Dipicolinic Acid Uptake into Developing Spores of Bacillus Subtilis Journal of Bacteriology. Jan, 2002 | Pubmed ID: 11751839 Visualization of Germinosomes and the Inner Membrane in Bacillus subtilis Spores Juan Wen1, Raymond Pasman1, Erik M.M. Manders*2,3, Peter Setlow*4, Stanley Brul*1 1Molecular Biology and Microbial Food Safety, Swammerdam Institute for Life Sciences, University of Amsterdam, 2Van Leeuwenhoek Centre for Advanced Microscopy, Swammerdam Institute for Life Sciences, University of Amsterdam, 3Confocal.nl BV., 4Dept. of Molecular Biology and Biophysics, UConn Health JoVE 59388 Bioengineering The Portable Chemical Sterilizer (PCS), D-FENS, and D-FEND ALL: Novel Chlorine Dioxide Decontamination Technologies for the Military Christopher J. Doona1, Florence E. Feeherry1, Peter Setlow2, Alexander J. Malkin3, Terrence J. Leighton4 1United States Army-Natick Soldier RD&E Center, Warfighter Directorate, 2Department of Molecular Biology and Biophysics, University of Connecticut Health Center, 3Lawrence Livermore National Laboratory, 4Children's Hospital Oakland Research Institute JoVE 4354 Bioengineering
Visualization of Germinosomes and the Inner Membrane in Bacillus subtilis Spores Juan Wen1, Raymond Pasman1, Erik M.M. Manders*2,3, Peter Setlow*4, Stanley Brul*1 1Molecular Biology and Microbial Food Safety, Swammerdam Institute for Life Sciences, University of Amsterdam, 2Van Leeuwenhoek Centre for Advanced Microscopy, Swammerdam Institute for Life Sciences, University of Amsterdam, 3Confocal.nl BV., 4Dept. of Molecular Biology and Biophysics, UConn Health JoVE 59388 Bioengineering
The Portable Chemical Sterilizer (PCS), D-FENS, and D-FEND ALL: Novel Chlorine Dioxide Decontamination Technologies for the Military Christopher J. Doona1, Florence E. Feeherry1, Peter Setlow2, Alexander J. Malkin3, Terrence J. Leighton4 1United States Army-Natick Soldier RD&E Center, Warfighter Directorate, 2Department of Molecular Biology and Biophysics, University of Connecticut Health Center, 3Lawrence Livermore National Laboratory, 4Children's Hospital Oakland Research Institute JoVE 4354 Bioengineering