Sharon Y.R. Dent Department of Molecular Carcinogenesis and Center for Cancer Epigenetics University of Texas M.D. Anderson Cancer Center Biography Publications Institution JoVE Articles Sharon Y.R. Dent has not added a biography. If you are Sharon Y.R. Dent and would like to personalize this page please email our Author Liaison for assistance. Publications Gcn5 Loss-of-function Accelerates Cerebellar and Retinal Degeneration in a SCA7 Mouse Model Human Molecular Genetics. Jan, 2012 | Pubmed ID: 22002997 Chromatin Signaling to Kinetochores: Transregulation of Dam1 Methylation by Histone H2B Ubiquitination Cell. Sep, 2011 | Pubmed ID: 21884933 USP22 Regulates Cell Proliferation by Deubiquitinating the Transcriptional Regulator FBP1 EMBO Reports. Sep, 2011 | Pubmed ID: 21779003 Hyperexpansion of GAA Repeats Affects Post-initiation Steps of FXN Transcription in Friedreich's Ataxia Nucleic Acids Research. Oct, 2011 | Pubmed ID: 21745819 Ubp8 and SAGA Regulate Snf1 AMP Kinase Activity Molecular and Cellular Biology. Aug, 2011 | Pubmed ID: 21628526 Protein-arginine Methyltransferase 1 (PRMT1) Methylates Ash2L, a Shared Component of Mammalian Histone H3K4 Methyltransferase Complexes The Journal of Biological Chemistry. Apr, 2011 | Pubmed ID: 21285357 Distinct Roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in Nuclear Receptor Transactivation The EMBO Journal. Jan, 2011 | Pubmed ID: 21131905 Multiple Faces of the SAGA Complex Current Opinion in Cell Biology. Jun, 2010 | Pubmed ID: 20363118 R Loops Stimulate Genetic Instability of CTG.CAG Repeats Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 20080737 Regulation of the Osteoblast-specific Transcription Factor Osterix by NO66, a Jumonji Family Histone Demethylase The EMBO Journal. Jan, 2010 | Pubmed ID: 19927124 Gcn5 and SAGA Regulate Shelterin Protein Turnover and Telomere Maintenance Molecular Cell. Aug, 2009 | Pubmed ID: 19683498 The H2BK123Rgument The Journal of Cell Biology. Aug, 2009 | Pubmed ID: 19667125 The HP1alpha-CAF1-SetDB1-containing Complex Provides H3K9me1 for Suv39-mediated K9me3 in Pericentric Heterochromatin EMBO Reports. Jul, 2009 | Pubmed ID: 19498464 Proper Gcn5 Histone Acetyltransferase Expression is Required for Normal Anteroposterior Patterning of the Mouse Skeleton Development, Growth & Differentiation. Jun, 2008 | Pubmed ID: 18430026 Tousled-mediated Activation of Aurora B Kinase Does Not Require Tousled Kinase Activity in Vivo The Journal of Biological Chemistry. May, 2008 | Pubmed ID: 18334486 Proper Expression of the Gcn5 Histone Acetyltransferase is Required for Neural Tube Closure in Mouse Embryos Developmental Dynamics : an Official Publication of the American Association of Anatomists. Apr, 2008 | Pubmed ID: 18330926 Cross-regulation of Histone Modifications Nature Structural & Molecular Biology. Nov, 2007 | Pubmed ID: 17984964 A Two-way Street: LSD1 Regulates Chromatin Boundary Formation in S. Pombe and Drosophila Molecular Cell. Apr, 2007 | Pubmed ID: 17466618 Developmental Potential of Gcn5(-/-) Embryonic Stem Cells in Vivo and in Vitro Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jun, 2007 | Pubmed ID: 17440986 Loss of Gcn5 Acetyltransferase Activity Leads to Neural Tube Closure Defects and Exencephaly in Mouse Embryos Molecular and Cellular Biology. May, 2007 | Pubmed ID: 17325035 Transcriptional Repression by Tup1-Ssn6 Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Aug, 2006 | Pubmed ID: 16936817 Functions of Histone-modifying Enzymes in Development Current Opinion in Genetics & Development. Apr, 2006 | Pubmed ID: 16503130 No Spt6, No Nucleosomes, No Activator Required Molecular Cell. Feb, 2006 | Pubmed ID: 16483927 The Set2 Methyltransferase Associates with Ssn6 Yet Tup1-Ssn6 Repression is Independent of Histone Methylation Biochemical and Biophysical Research Communications. Jan, 2006 | Pubmed ID: 16329992 Histone Modifying Enzymes and Cancer: Going Beyond Histones Journal of Cellular Biochemistry. Dec, 2005 | Pubmed ID: 16173079 The Set1 Methyltransferase Opposes Ipl1 Aurora Kinase Functions in Chromosome Segregation Cell. Sep, 2005 | Pubmed ID: 16143104 GCN5 and P300 Share Essential Functions During Early Embryogenesis Developmental Dynamics : an Official Publication of the American Association of Anatomists. Aug, 2005 | Pubmed ID: 15937931 Histone Modifications in Corepressor Functions Current Topics in Developmental Biology. 2004 | Pubmed ID: 14975250 Resetting the Histone Code at CDKN2A in HNSCC by Inhibition of DNA Methylation Oncogene. Dec, 2003 | Pubmed ID: 14654786 Tup1-Ssn6 Interacts with Multiple Class I Histone Deacetylases in Vivo The Journal of Biological Chemistry. Dec, 2003 | Pubmed ID: 14525981 C-Myc Transformation Domain Recruits the Human STAGA Complex and Requires TRRAP and GCN5 Acetylase Activity for Transcription Activation The Journal of Biological Chemistry. May, 2003 | Pubmed ID: 12660246 Physical and Functional Interaction of the Yeast Corepressor Tup1 with MRNA 5'-triphosphatase The Journal of Biological Chemistry. May, 2003 | Pubmed ID: 12637515 Site-specific Loss of Acetylation Upon Phosphorylation of Histone H3 The Journal of Biological Chemistry. Aug, 2002 | Pubmed ID: 12039950 Transcriptional Control: an Activating Role for Arginine Methylation Current Biology : CB. Jan, 2002 | Pubmed ID: 11818080 Histone-dependent Association of Tup1-Ssn6 with Repressed Genes in Vivo Molecular and Cellular Biology. Feb, 2002 | Pubmed ID: 11784848 Selecting and Isolating Colonies of Human Induced Pluripotent Stem Cells Reprogrammed from Adult Fibroblasts Urszula Polak1,2, Calley Hirsch1, Sherman Ku3, Joel Gottesfeld3, Sharon Y.R. Dent1, Marek Napierala1 1Department of Molecular Carcinogenesis and Center for Cancer Epigenetics, University of Texas M.D. Anderson Cancer Center, 2Department of Cell Biology, Poznan University of Medical Sciences, 3Department of Molecular Biology, The Scripps Research Institute JoVE 3416 Biology
Selecting and Isolating Colonies of Human Induced Pluripotent Stem Cells Reprogrammed from Adult Fibroblasts Urszula Polak1,2, Calley Hirsch1, Sherman Ku3, Joel Gottesfeld3, Sharon Y.R. Dent1, Marek Napierala1 1Department of Molecular Carcinogenesis and Center for Cancer Epigenetics, University of Texas M.D. Anderson Cancer Center, 2Department of Cell Biology, Poznan University of Medical Sciences, 3Department of Molecular Biology, The Scripps Research Institute JoVE 3416 Biology