Simon M. Petersen-Jones College of Veterinary Medicine, Department of Small Animal Clinical Sciences Michigan State University Biography Publications Institution JoVE Articles Simon M. Petersen-Jones has not added a biography. If you are Simon M. Petersen-Jones and would like to personalize this page please email our Author Liaison for assistance. Publications CNGB1-related Rod-cone Dystrophy: A Mutation Review and Update Human Mutation. Jun, 2021 | Pubmed ID: 33847019 ERG Assessment of Altered Retinal Function in Canine Models of Retinitis Pigmentosa and Monitoring of Response to Translatable Gene Augmentation Therapy Documenta Ophthalmologica. Advances in Ophthalmology. Apr, 2021 | Pubmed ID: 33818677 Comparison of Developmental Dynamics in Human Fetal Retina and Human Pluripotent Stem Cell-Derived Retinal Tissue Stem Cells and Development. 04, 2021 | Pubmed ID: 33677999 Novel AAV Capsids for Intravitreal Gene Therapy of Photoreceptor Disorders EMBO Molecular Medicine. Apr, 2021 | Pubmed ID: 33616280 A Comprehensive Study of the Retinal Phenotype of Rpe65-Deficient Dogs Cells. Jan, 2021 | Pubmed ID: 33435495 Pluripotent Stem Cell-Based Organoid Technologies for Developing Next-Generation Vision Restoration Therapies of Blindness Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics. 04, 2021 | Pubmed ID: 33052761 A Missense Variant Is Associated with Canine Laryngeal Paralysis and Polyneuropathy Genes. 11, 2020 | Pubmed ID: 33261176 Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium Translational Vision Science & Technology. 06, 2020 | Pubmed ID: 32832209 A Novel Mutation in PDE6B in Spanish Water Dogs with Early-onset Progressive Retinal Atrophy Veterinary Ophthalmology. Sep, 2020 | Pubmed ID: 32639685 Changes in Retinal Layer Thickness with Maturation in the Dog: an in Vivo Spectral Domain - Optical Coherence Tomography Imaging Study BMC Veterinary Research. Jun, 2020 | Pubmed ID: 32605619 Mutations in the Kinesin-2 Motor KIF3B Cause an Autosomal-Dominant Ciliopathy American Journal of Human Genetics. 06, 2020 | Pubmed ID: 32386558 Large Animal Models of Inherited Retinal Degenerations: A Review Cells. 04, 2020 | Pubmed ID: 32260251 A Review of Electroretinography Waveforms and Models and Their Application in the Dog Veterinary Ophthalmology. May, 2020 | Pubmed ID: 32196872 Development of a Protocol for Maintaining Viability While Shipping Organoid-derived Retinal Tissue Journal of Tissue Engineering and Regenerative Medicine. 02, 2020 | Pubmed ID: 31908157 Sildenafil Administration in Dogs Heterozygous for A Functional Null Mutation in Pde6a: Suppressed Rod-Mediated ERG Responses and Apparent Retinal Outer Nuclear Layer Thinning Advances in Experimental Medicine and Biology. 2019 | Pubmed ID: 31884640 Advancing Gene Therapy for PDE6A Retinitis Pigmentosa Advances in Experimental Medicine and Biology. 2019 | Pubmed ID: 31884596 Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in the Subretinal Space of the Cat Eye Stem Cells and Development. 09, 2019 | Pubmed ID: 31210100 CORRELATIONS BETWEEN EXPERIMENTAL MYOPIA MODELS AND HUMAN PATHOLOGIC MYOPIA Retina (Philadelphia, Pa.). Apr, 2019 | Pubmed ID: 30586351 Physiological Characterization of Ocular Melanosis-affected Canine Melanocytes Veterinary Ophthalmology. Mar, 2019 | Pubmed ID: 29701286 Retinal-chitosan Conjugates Effectively Deliver Active Chromophores to Retinal Photoreceptor Cells in Blind Mice and Dogs Molecular Pharmacology. 05, 2018 | Pubmed ID: 29453250 Patients and Animal Models of CNGβ1-deficient Retinitis Pigmentosa Support Gene Augmentation Approach The Journal of Clinical Investigation. 01, 2018 | Pubmed ID: 29202463 Gene Supplementation Rescues Rod Function and Preserves Photoreceptor and Retinal Morphology in Dogs, Leading the Way Toward Treating Human -Retinitis Pigmentosa Human Gene Therapy. Dec, 2017 | Pubmed ID: 29212382 Birth of Clones of the World's First Cloned Dog Scientific Reports. 11, 2017 | Pubmed ID: 29127382 Early-Onset Progressive Degeneration of the Area Centralis in RPE65-Deficient Dogs Investigative Ophthalmology & Visual Science. 06, 2017 | Pubmed ID: 28662231 Assessment of Rod, Cone, and Intrinsically Photosensitive Retinal Ganglion Cell Contributions to the Canine Chromatic Pupillary Response Investigative Ophthalmology & Visual Science. 01, 2017 | Pubmed ID: 28061512 A Tool Set to Allow Rapid Screening of Dog Families with PRA for Association with Candidate Genes Veterinary Ophthalmology. Jul, 2017 | Pubmed ID: 27317651 CrxRdy Cat: A Large Animal Model for CRX-Associated Leber Congenital Amaurosis Investigative Ophthalmology & Visual Science. Jul, 2016 | Pubmed ID: 27427859 An Association Between Systemic Cyclosporine Administration and Development of Acute Bullous Keratopathy in Cats Veterinary Ophthalmology. Jul, 2016 | Pubmed ID: 26880480 Progressive Retinal Atrophy in the Polski Owczarek Nizinny Dog: a Clinical and Genetic Study Veterinary Ophthalmology. May, 2016 | Pubmed ID: 26009980 Genetics of Canine Primary Glaucomas The Veterinary Clinics of North America. Small Animal Practice. Nov, 2015 | Pubmed ID: 26277300 Long-term Effect of Gene Therapy on Leber's Congenital Amaurosis The New England Journal of Medicine. May, 2015 | Pubmed ID: 25938638 Dog Models for Blinding Inherited Retinal Dystrophies Human Gene Therapy. Clinical Development. Mar, 2015 | Pubmed ID: 25671556 Isolation and Cultivation of Canine Uveal Melanocytes Veterinary Ophthalmology. Jul, 2015 | Pubmed ID: 25176505 Altered Fundus Appearance Resulting from Autofluorescence Imaging with the Confocal Scanning Laser Ophthalmoscope (cSLO) in Cats Veterinary Ophthalmology. Sep, 2014 | Pubmed ID: 24995729 A Partial Gene Deletion of SLC45A2 Causes Oculocutaneous Albinism in Doberman Pinscher Dogs PloS One. 2014 | Pubmed ID: 24647637 Successful Gene Therapy in Older Rpe65-deficient Dogs Following Subretinal Injection of an Adeno-associated Vector Expressing RPE65 Human Gene Therapy. Oct, 2013 | Pubmed ID: 24028205 A Large Animal Model for CNGB1 Autosomal Recessive Retinitis Pigmentosa PloS One. 2013 | Pubmed ID: 23977260 Evaluation of Lateral Spread of Transgene Expression Following Subretinal AAV-mediated Gene Delivery in Dogs PloS One. 2013 | Pubmed ID: 23560080 Exclusion of Eleven Candidate Genes for Ocular Melanosis in Cairn Terriers Journal of Negative Results in Biomedicine. Mar, 2013 | Pubmed ID: 23448350 A Facemask for Gaseous Anesthesia in Laboratory Rodents and Chicks That Allows Easy Access to the Eyes for Ophthalmic Procedures Veterinary Ophthalmology. Jul, 2013 | Pubmed ID: 23066660 Viral Vectors for Targeting the Canine Retina: a Review Veterinary Ophthalmology. Sep, 2012 | Pubmed ID: 22882429 Bilateral Uveal Metastasis of a Subcutaneous Fibrosarcoma in a Cat Veterinary Ophthalmology. Nov, 2012 | Pubmed ID: 22360781 Gene Augmentation Trials Using the Rpe65-deficient Dog: Contributions Towards Development and Refinement of Human Clinical Trials Advances in Experimental Medicine and Biology. 2012 | Pubmed ID: 22183331 Improvement of Visual Performance with Intravitreal Administration of 9-cis-retinal in Rpe65-mutant Dogs Archives of Ophthalmology (Chicago, Ill. : 1960). Nov, 2010 | Pubmed ID: 20837787 AAV Retinal Transduction in a Large Animal Model Species: Comparison of a Self-complementary AAV2/5 with a Single-stranded AAV2/5 Vector Molecular Vision. Sep, 2009 | Pubmed ID: 19756181 Characterization of a Canine Model of Autosomal Recessive Retinitis Pigmentosa Due to a PDE6A Mutation Investigative Ophthalmology & Visual Science. Feb, 2009 | Pubmed ID: 18775863 Topographical Characterization of Cone Photoreceptors and the Area Centralis of the Canine Retina Molecular Vision. 2008 | Pubmed ID: 19112529 A Novel Method for Objective Vision Testing in Canine Models of Inherited Retinal Disease Investigative Ophthalmology & Visual Science. Aug, 2008 | Pubmed ID: 18660425 Ocular Melanosis in the Cairn Terrier: Histopathological Description of the Condition, and Immunohistological and Ultrastructural Characterization of the Characteristic Pigment-laden Cells Veterinary Ophthalmology. Jul-Aug, 2008 | Pubmed ID: 18638353 Ocular Melanosis in the Cairn Terrier: Clinical Description and Investigation of Mode of Inheritance Veterinary Ophthalmology. Nov-Dec, 2007 | Pubmed ID: 17973836 Electroretinographic Features of the Retinopathy, Globe Enlarged (rge) Chick Phenotype Molecular Vision. Apr, 2007 | Pubmed ID: 17438521 Postnatal Development of Canine Axial Globe Length Measured by B-scan Ultrasonography Veterinary Ophthalmology. Jan-Feb, 2007 | Pubmed ID: 17204121 Influence of Recording Electrode Type and Reference Electrode Position on the Canine Electroretinogram Documenta Ophthalmologica. Advances in Ophthalmology. Sep, 2005 | Pubmed ID: 16514491 Assessment of the Dark-adaptation Time Required for Recovery of Electroretinographic Responses in Dogs After Fundus Photography and Indirect Ophthalmoscopy American Journal of Veterinary Research. Oct, 2005 | Pubmed ID: 16273914 Detailed Histopathologic Characterization of the Retinopathy, Globe Enlarged (rge) Chick Phenotype Molecular Vision. Jan, 2005 | Pubmed ID: 15660021 An Improved DNA-based Test for Detection of the Codon 616 Mutation in the Alpha Cyclic GMP Phosphodiesterase Gene That Causes Progressive Retinal Atrophy in the Cardigan Welsh Corgi Veterinary Ophthalmology. Jun, 2002 | Pubmed ID: 12071867 Sudden Acquired Retinal Degeneration Syndrome (SARDS) - a Review and Proposed Strategies Toward a Better Understanding of Pathogenesis, Early Diagnosis, and Therapy Veterinary Ophthalmology. | Pubmed ID: 26096588 Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model Laurence M. Occelli*1, Felipe Marinho*1, Ratnesh K. Singh2, Francois Binette2, Igor O. Nasonkin2, Simon M. Petersen-Jones1 1College of Veterinary Medicine, Department of Small Animal Clinical Sciences, Michigan State University, 2Lineage Cell Therapeutics, Inc. JoVE 61683 Neuroscience
Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model Laurence M. Occelli*1, Felipe Marinho*1, Ratnesh K. Singh2, Francois Binette2, Igor O. Nasonkin2, Simon M. Petersen-Jones1 1College of Veterinary Medicine, Department of Small Animal Clinical Sciences, Michigan State University, 2Lineage Cell Therapeutics, Inc. JoVE 61683 Neuroscience