Simone Sidoli Department of Biochemistry Albert Einstein College of Medicine Biography Publications Institution JoVE Articles Simone Sidoli has not added a biography. If you are Simone Sidoli and would like to personalize this page please email our Author Liaison for assistance. Publications Prophylactic Effect of Chronic Immunosuppression in a Mouse Model of CSF-1 Receptor-related Leukoencephalopathy Glia. Jul, 2023 | Pubmed ID: 37519044 Dynamic Network-guided CRISPRi Screen Identifies CTCF-loop-constrained Nonlinear Enhancer Gene Regulatory Activity During Cell State Transitions Nature Genetics. Aug, 2023 | Pubmed ID: 37488417 Proteomics and Phosphoproteomics Profiling in Glutamatergic Neurons and Microglia in an IPSC Model of Jansen De Vries Syndrome BioRxiv : the Preprint Server for Biology. Jul, 2023 | Pubmed ID: 37461463 Tet2 Regulates Sin3a Recruitment at Active Enhancers in Embryonic Stem Cells IScience. Jul, 2023 | Pubmed ID: 37456851 TMEM106B Puncta Is Increased in Multiple Sclerosis Plaques, and Reduced Protein in Mice Results in Delayed Lipid Clearance Following CNS Injury Cells. Jun, 2023 | Pubmed ID: 37443768 Dynamic De Novo Heterochromatin Assembly and Disassembly at Replication Forks Ensures Fork Stability Nature Cell Biology. Jul, 2023 | Pubmed ID: 37414849 MTORC2-NDRG1-CDC42 Axis Couples Fasting to Mitochondrial Fission Nature Cell Biology. Jul, 2023 | Pubmed ID: 37386153 Structural and Mechanistic Basis of Neutralization by a Pan-hantavirus Protective Antibody Science Translational Medicine. Jun, 2023 | Pubmed ID: 37315110 The Role of Histone H3 Lysine Demethylases in Glioblastoma Cancer Metastasis Reviews. Jun, 2023 | Pubmed ID: 37286866 Epigenetic Dysregulation from Chromosomal Transit in Micronuclei Nature. Jul, 2023 | Pubmed ID: 37286593 Orally Administered Sodium Nitrite Prevents the Increased α-1 Adrenergic Vasoconstriction Induced by Hypertension and Promotes the S-nitrosylation of Calcium/calmodulin-dependent Protein Kinase II Biochemical Pharmacology. Jun, 2023 | Pubmed ID: 37127250 DPP4 Inhibition Impairs Senohemostasis to Improve Plaque Stability in Atherosclerotic Mice The Journal of Clinical Investigation. Jun, 2023 | Pubmed ID: 37097759 HSV-2 Triggers Upregulation of MALAT1 in CD4+ T Cells and Promotes HIV Latency Reversal The Journal of Clinical Investigation. Jun, 2023 | Pubmed ID: 37079384 PROTAC-Mediated Selective Degradation of Cytosolic Soluble Epoxide Hydrolase Enhances ER Stress Reduction ACS Chemical Biology. Apr, 2023 | Pubmed ID: 36947831 MAT Gain of Activity Mutation in Is Associated with Resistance to MTAN Transition State Analogues ACS Infectious Diseases. Apr, 2023 | Pubmed ID: 36920074 Expanding the Epitranscriptomic RNA Sequencing and Modification Mapping Mass Spectrometry Toolbox with Field Asymmetric Waveform Ion Mobility and Electrochemical Elution Liquid Chromatography Analytical Chemistry. Mar, 2023 | Pubmed ID: 36916610 Proximity Labeling Reveals a New in Vivo Network of Interactors for the Histone Demethylase KDM5 Epigenetics & Chromatin. Feb, 2023 | Pubmed ID: 36803422 Post-Translational Modifications of Histone Variants in the Absence and Presence of a Methionine-Depleting Enzyme in Normal and Cancer Cells Cancers. Jan, 2023 | Pubmed ID: 36672476 Investigation of Reversible Histone Acetylation and Dynamics in Gene Expression Regulation Using 3D Liver Spheroid Model Epigenetics & Chromatin. Nov, 2022 | Pubmed ID: 36411440 Endocrine Resistance and Breast Cancer Plasticity Are Controlled by CoREST Nature Structural & Molecular Biology. Nov, 2022 | Pubmed ID: 36344844 Morphine Disrupts Macrophage Functions Even During HIV Infection Journal of Leukocyte Biology. Nov, 2022 | Pubmed ID: 36205434 Autophagic State Prospectively Identifies Facultative Stem Cells in the Intestinal Epithelium EMBO Reports. Nov, 2022 | Pubmed ID: 36120829 Reduced Endosomal Microautophagy Activity in Aging Associates with Enhanced Exocyst-mediated Protein Secretion Aging Cell. Oct, 2022 | Pubmed ID: 36116133 CRISPR Screening Uncovers a Central Requirement for HHEX in Pancreatic Lineage Commitment and Plasticity Restriction Nature Cell Biology. Jul, 2022 | Pubmed ID: 35787684 Methamphetamine Dysregulates Macrophage Functions and Autophagy to Mediate HIV Neuropathogenesis Biomedicines. May, 2022 | Pubmed ID: 35740279 Dense Granule Protein GRA64 Interacts with Host Cell ESCRT Proteins During Infection MBio. Aug, 2022 | Pubmed ID: 35730903 Altered Abundances of Human Immunoglobulin M and Immunoglobulin G Subclasses in Alzheimer's Disease Frontal Cortex Scientific Reports. Apr, 2022 | Pubmed ID: 35484384 The Transcription Factor PAX8 Promotes Angiogenesis in Ovarian Cancer Through Interaction with SOX17 Science Signaling. Apr, 2022 | Pubmed ID: 35380877 Macrophages Use Apoptotic Cell-derived Methionine and DNMT3A During Efferocytosis to Promote Tissue Resolution Nature Metabolism. Apr, 2022 | Pubmed ID: 35361955 Synthesis and Characterization of Transition-State Analogue Inhibitors Against Human DNA Methyltransferase 1 Journal of Medicinal Chemistry. Apr, 2022 | Pubmed ID: 35324190 CpG Island Reconfiguration for the Establishment and Synchronization of Polycomb Functions Upon Exit from Naive Pluripotency Molecular Cell. 03, 2022 | Pubmed ID: 35202573 A Dynamic and Combinatorial Histone Code Drives Malaria Parasite Asexual and Sexual Development Molecular & Cellular Proteomics : MCP. Mar, 2022 | Pubmed ID: 35051657 Multi-omic Profiling of Histone Variant H3.3 Lysine 27 Methylation Reveals a Distinct Role from Canonical H3 in Stem Cell Differentiation Molecular Omics. Jan, 2022 | Pubmed ID: 35044400 Genotype-specific Features Reduce the Susceptibility of South American Yellow Fever Virus Strains to Vaccine-induced Antibodies Cell Host & Microbe. 02, 2022 | Pubmed ID: 34998466 Type I and II PRMTs Inversely Regulate Post-transcriptional Intron Detention Through Sm and CHTOP Methylation ELife. 01, 2022 | Pubmed ID: 34984976 Pipecolic Acid, a Putative Mediator of the Encephalopathy of Cerebral Malaria and the Experimental Model of Cerebral Malaria The Journal of Infectious Diseases. Feb, 2022 | Pubmed ID: 34932816 Quantitative Subcellular Acyl-CoA Analysis Reveals Distinct Nuclear Metabolism and Isoleucine-dependent Histone Propionylation Molecular Cell. 01, 2022 | Pubmed ID: 34856123 DNA Methylation and Hydroxymethylation Analysis Using a High Throughput and Low Bias Direct Injection Mass Spectrometry Platform MethodsX. 2021 | Pubmed ID: 35004218 A Key Silencing Histone Mark on Chromatin Is Lost When Colorectal Adenocarcinoma Cells Are Depleted of Methionine by Methionine γ-Lyase Frontiers in Molecular Biosciences. 2021 | Pubmed ID: 34660696 High Throughput and Low Bias DNA Methylation and Hydroxymethylation Analysis by Direct Injection Mass Spectrometry Analytica Chimica Acta. Oct, 2021 | Pubmed ID: 34538324 Independent Transcriptomic and Proteomic Regulation by Type I and II Protein Arginine Methyltransferases IScience. Sep, 2021 | Pubmed ID: 34505004 The Polycomb Protein RING1B Enables Estrogen-mediated Gene Expression by Promoting Enhancer-promoter Interaction and R-loop Formation Nucleic Acids Research. 09, 2021 | Pubmed ID: 34428304 VAL Genes Regulate Vegetative Phase Change Via MiR156-dependent and Independent Mechanisms PLoS Genetics. 06, 2021 | Pubmed ID: 34181637 Protective Neutralizing Antibodies from Human Survivors of Crimean-Congo Hemorrhagic Fever Cell. 06, 2021 | Pubmed ID: 34077751 Author Correction: Long-term Behavioral and Cell-type-specific Molecular Effects of Early Life Stress Are Mediated by H3K79me2 Dynamics in Medium Spiny Neurons Nature Neuroscience. May, 2021 | Pubmed ID: 33833436 QSER1 Protects DNA Methylation Valleys from De Novo Methylation Science (New York, N.Y.). 04, 2021 | Pubmed ID: 33833093 Long-term Behavioral and Cell-type-specific Molecular Effects of Early Life Stress Are Mediated by H3K79me2 Dynamics in Medium Spiny Neurons Nature Neuroscience. 05, 2021 | Pubmed ID: 33723435 One-shot Analysis of Translated Mammalian LncRNAs with AHARIBO ELife. 02, 2021 | Pubmed ID: 33594971 H1 Histones Control the Epigenetic Landscape by Local Chromatin Compaction Nature. 01, 2021 | Pubmed ID: 33299182 White Adipose Remodeling During Browning in Mice Involves YBX1 to Drive Thermogenic Commitment Molecular Metabolism. 02, 2021 | Pubmed ID: 33285300 A Workflow for Ultra-rapid Analysis of Histone Post-translational Modifications with Direct-injection Mass Spectrometry Bio-protocol. Sep, 2020 | Pubmed ID: 33659415 Toxoplasma Gondii PPM3C, a Secreted Protein Phosphatase, Affects Parasitophorous Vacuole Effector Export PLoS Pathogens. 12, 2020 | Pubmed ID: 33370417 Author Correction: An Integrated Multi-omics Approach Identifies Epigenetic Alterations Associated with Alzheimer's Disease Nature Genetics. Nov, 2020 | Pubmed ID: 33033384 An Integrated Multi-omics Approach Identifies Epigenetic Alterations Associated with Alzheimer's Disease Nature Genetics. 10, 2020 | Pubmed ID: 32989324 Guide for Protein Fold Change and P-value Calculation for Non-experts in Proteomics Molecular Omics. 12, 2020 | Pubmed ID: 32968743 Phosphoproteomic Analysis of Rat Neutrophils Shows the Effect of Intestinal Ischemia/Reperfusion and Preconditioning on Kinases and Phosphatases International Journal of Molecular Sciences. Aug, 2020 | Pubmed ID: 32823483 Nuclear RNAi Factor SET-32 Deposits the Transgenerational Histone Modification, H3K23me3 ELife. 08, 2020 | Pubmed ID: 32804637 PR-DUB Maintains the Expression of Critical Genes Through FOXK1/2- and ASXL1/2/3-dependent Recruitment to Chromatin and H2AK119ub1 Deubiquitination Genome Research. 08, 2020 | Pubmed ID: 32747411 Mutant FOXL2 Hijacks SMAD4 and SMAD2/3 to Drive Adult Granulosa Cell Tumors Cancer Research. 09, 2020 | Pubmed ID: 32641411 Mass Spectrometry to Study Chromatin Compaction Biology. Jun, 2020 | Pubmed ID: 32604817 Disruption of ATRX-RNA Interactions Uncovers Roles in ATRX Localization and PRC2 Function Nature Communications. 05, 2020 | Pubmed ID: 32376827 Comprehensive Map of the Artemisia Annua Proteome and Quantification of Differential Protein Expression in Chemotypes Producing High Versus Low Content of Artemisinin Proteomics. 05, 2020 | Pubmed ID: 32311217 Lysine 4 of Histone H3.3 is Required for Embryonic Stem Cell Differentiation, Histone Enrichment at Regulatory Regions and Transcription Accuracy Nature Genetics. 03, 2020 | Pubmed ID: 32139906 Bullet Points to Evaluate the Performance of the Middle-down Proteomics Workflow for Histone Modification Analysis Methods (San Diego, Calif.). 12, 2020 | Pubmed ID: 32070774 Histone H3K23-specific Acetylation by MORF is Coupled to H3K14 Acylation Nature Communications. 10, 2019 | Pubmed ID: 31624313 A Mass Spectrometry-based Assay Using Metabolic Labeling to Rapidly Monitor Chromatin Accessibility of Modified Histone Proteins Scientific Reports. 09, 2019 | Pubmed ID: 31541121 Quantitation of Single and Combinatorial Histone Modifications by Integrated Chromatography of Bottom-up Peptides and Middle-down Polypeptide Tails Journal of the American Society for Mass Spectrometry. Dec, 2019 | Pubmed ID: 31512222 An HDAC3-PROX1 Corepressor Module Acts on HNF4α to Control Hepatic Triglycerides Nature Communications. Sep, 2017 | Pubmed ID: 28916805 Phosphoproteomics Reveals That Glycogen Synthase Kinase-3 Phosphorylates Multiple Splicing Factors and is Associated with Alternative Splicing The Journal of Biological Chemistry. Sep, 2017 | Pubmed ID: 28916722 Proteome-wide Acetylation Dynamics in Human Cells Scientific Reports. Aug, 2017 | Pubmed ID: 28860605 Identification of Nidogen 1 As a Lung Metastasis Protein Through Secretome Analysis Genes & Development. Jul, 2017 | Pubmed ID: 28827399 Metabolic Labeling in Middle-down Proteomics Allows for Investigation of the Dynamics of the Histone Code Epigenetics & Chromatin. Jul, 2017 | Pubmed ID: 28683815 Middle-down Proteomics: a Still Unexploited Resource for Chromatin Biology Expert Review of Proteomics. Jul, 2017 | Pubmed ID: 28649883 Quantitative Chromatin Proteomics Reveals a Dynamic Histone Post-translational Modification Landscape That Defines Asexual and Sexual Plasmodium Falciparum Parasites Scientific Reports. Apr, 2017 | Pubmed ID: 28377601 Abnormal Levels of Histone Methylation in the Retinas of Diabetic Rats Are Reversed by Minocycline Treatment Scientific Reports. Mar, 2017 | Pubmed ID: 28338045 Multicellular Tumor Spheroids Combined with Mass Spectrometric Histone Analysis To Evaluate Epigenetic Drugs Analytical Chemistry. Mar, 2017 | Pubmed ID: 28194967 Time-resolved Global and Chromatin Proteomics During Herpes Simplex Virus Type 1 (HSV-1) Infection Molecular & Cellular Proteomics : MCP. Apr, 2017 | Pubmed ID: 28179408 Roles of H3K27me2 and H3K27me3 Examined During Fate Specification of Embryonic Stem Cells Cell Reports. Jan, 2017 | Pubmed ID: 28052258 Why Proteomics is Not the New Genomics and the Future of Mass Spectrometry in Cell Biology The Journal of Cell Biology. Jan, 2017 | Pubmed ID: 27956468 Characterization of Individual Histone Posttranslational Modifications and Their Combinatorial Patterns by Mass Spectrometry-Based Proteomics Strategies Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 27854019 Nuclear Phosphoproteome Analysis of 3T3-L1 Preadipocyte Differentiation Reveals System-wide Phosphorylation of Transcriptional Regulators Proteomics. Mar, 2017 | Pubmed ID: 27717184 High Performance Mass Spectrometry Based Proteomics Reveals Enzyme and Signaling Pathway Regulation in Neutrophils During the Early Stage of Surgical Trauma Proteomics. Clinical Applications. Jan, 2017 | Pubmed ID: 27672009 Roles of H3K27me2 and H3K27me3 Examined During Fate Specification of Embryonic Stem Cells Cell Reports. Oct, 2016 | Pubmed ID: 27783950 High-Resolution Mapping of RNA-Binding Regions in the Nuclear Proteome of Embryonic Stem Cells Molecular Cell. Oct, 2016 | Pubmed ID: 27768875 Systems Level Analysis of Histone H3 Post-translational Modifications (PTMs) Reveals Features of PTM Crosstalk in Chromatin Regulation Molecular & Cellular Proteomics : MCP. Aug, 2016 | Pubmed ID: 27302890 Differential Quantification of Isobaric Phosphopeptides Using Data-independent Acquisition Mass Spectrometry Molecular BioSystems. Jul, 2016 | Pubmed ID: 27301801 Multiplexed Data Independent Acquisition (MSX-DIA) Applied by High Resolution Mass Spectrometry Improves Quantification Quality for the Analysis of Histone Peptides Proteomics. Aug, 2016 | Pubmed ID: 27193262 Histone H4 Acetylation and the Epigenetic Reader Brd4 Are Critical Regulators of Pluripotency in Embryonic Stem Cells BMC Genomics. 2016 | Pubmed ID: 26847871 Analyses of Histone Proteoforms Using Front-end Electron Transfer Dissociation-enabled Orbitrap Instruments Molecular & Cellular Proteomics : MCP. Mar, 2016 | Pubmed ID: 26785730 Histone Modification Profiling Reveals Differential Signatures Associated with Human Embryonic Stem Cell Self-renewal and Differentiation Proteomics. Feb, 2016 | Pubmed ID: 26631989 Loss of HP1 Causes Depletion of H3K27me3 from Facultative Heterochromatin and Gain of H3K27me2 at Constitutive Heterochromatin Genome Research. Jan, 2016 | Pubmed ID: 26537359 Dynamic Changes of Histone H3 Marks During Caenorhabditis Elegans Lifecycle Revealed by Middle-down Proteomics Proteomics. Feb, 2016 | Pubmed ID: 26508544 Low Resolution Data-Independent Acquisition in an LTQ-Orbitrap Allows for Simplified and Fully Untargeted Analysis of Histone Modifications Analytical Chemistry. Nov, 2015 | Pubmed ID: 26505526 H3K23me2 is a New Heterochromatic Mark in Caenorhabditis Elegans Nucleic Acids Research. Nov, 2015 | Pubmed ID: 26476455 Tumor Suppressor ASXL1 is Essential for the Activation of INK4B Expression in Response to Oncogene Activity and Anti-proliferative Signals Cell Research. Nov, 2015 | Pubmed ID: 26470845 The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79 Molecular Cell. Oct, 2015 | Pubmed ID: 26439302 Top-down and Middle-down Protein Analysis Reveals That Intact and Clipped Human Histones Differ in Post-translational Modification Patterns Molecular & Cellular Proteomics : MCP. Dec, 2015 | Pubmed ID: 26424599 Progress in Epigenetic Histone Modification Analysis by Mass Spectrometry for Clinical Investigations Expert Review of Proteomics. 2015 | Pubmed ID: 26400466 Properly Reading the Histone Code by MS-based Proteomics Proteomics. Sep, 2015 | Pubmed ID: 26223514 Proteogenomics Analysis Reveals Specific Genomic Orientations of Distal Regulatory Regions Composed by Non-canonical Histone Variants Epigenetics & Chromatin. 2015 | Pubmed ID: 25878728 Quantitative Proteomics Analysis of Platelet-derived Microparticles Reveals Distinct Protein Signatures when Stimulated by Different Physiological Agonists Journal of Proteomics. May, 2015 | Pubmed ID: 25835965 EpiProfile Quantifies Histone Peptides With Modifications by Extracting Retention Time and Intensity in High-resolution Mass Spectra Molecular & Cellular Proteomics : MCP. Jun, 2015 | Pubmed ID: 25805797 Two Distinct Modes for Propagation of Histone PTMs Across the Cell Cycle Genes & Development. Mar, 2015 | Pubmed ID: 25792596 Bottom-up and Middle-down Proteomics Have Comparable Accuracies in Defining Histone Post-translational Modification Relative Abundance and Stoichiometry Analytical Chemistry. Mar, 2015 | Pubmed ID: 25719549 Drawbacks in the Use of Unconventional Hydrophobic Anhydrides for Histone Derivatization in Bottom-up Proteomics PTM Analysis Proteomics. May, 2015 | Pubmed ID: 25641854 Sequential Window Acquisition of All Theoretical Mass Spectra (SWATH) Analysis for Characterization and Quantification of Histone Post-translational Modifications Molecular & Cellular Proteomics : MCP. Sep, 2015 | Pubmed ID: 25636311 Defining Heterochromatin in C. Elegans Through Genome-wide Analysis of the Heterochromatin Protein 1 Homolog HPL-2 Genome Research. Jan, 2015 | Pubmed ID: 25467431 Middle-down Hybrid Chromatography/tandem Mass Spectrometry Workflow for Characterization of Combinatorial Post-translational Modifications in Histones Proteomics. Oct, 2014 | Pubmed ID: 25073878 Transcription Factor Cooperativity in Early Adipogenic Hotspots and Super-enhancers Cell Reports. Jun, 2014 | Pubmed ID: 24857652 Large Scale Analysis of Co-existing Post-translational Modifications in Histone Tails Reveals Global Fine Structure of Cross-talk Molecular & Cellular Proteomics : MCP. Jul, 2014 | Pubmed ID: 24741113 Comparative Proteomic Analysis of Histone Post-translational Modifications Upon Ischemia/reperfusion-induced Retinal Injury Journal of Proteome Research. Apr, 2014 | Pubmed ID: 24628298 KYSS: Mass Spectrometry Data Quality Assessment for Protein Analysis and Large-scale Proteomics Biochemical and Biophysical Research Communications. Mar, 2014 | Pubmed ID: 24480439 Precision Mapping of Coexisting Modifications in Histone H3 Tails from Embryonic Stem Cells by ETD-MS/MS Analytical Chemistry. Sep, 2013 | Pubmed ID: 23889513 The C. Elegans H3K27 Demethylase UTX-1 is Essential for Normal Development, Independent of Its Enzymatic Activity PLoS Genetics. 2012 | Pubmed ID: 22570628 Proteomics in Chromatin Biology and Epigenetics: Elucidation of Post-translational Modifications of Histone Proteins by Mass Spectrometry Journal of Proteomics. Jun, 2012 | Pubmed ID: 22234360 कार्यात्मक 3 डी स्फेरॉइड सेल संस्कृतियों का अर्ध-स्वचालित फेनोटाइपिक विश्लेषण Stephanie Stransky1, Dejauwne Young1, Karoline Mikkelsen2,3, Annemette Præstegaard Thulesen2, Helle Sedighi Frandsen3, Simone Sidoli1 1Department of Biochemistry, Albert Einstein College of Medicine, 2Department of Biochemistry and Molecular Biology, University of Southern Denmark, 3CelVivo ApS JoVE 65086 Biochemistry हेपेटिक ऊतक के 3 डी सेल संस्कृति मॉडल में हिस्टोन पोस्ट-ट्रांसलेशनल संशोधनों का वैश्विक स्तर का परिमाणीकरण Jazmine-Saskya N. Joseph-Chowdhury1, Stephanie Stransky1, Sarah Graff1, Ronald Cutler1, Dejauwne Young1, Julie S. Kim1, Carlos Madrid-Aliste1, Jennifer T. Aguilan1, Edward Nieves1, Yan Sun1, Edwin J. Yoo1, Simone Sidoli1 1Department of Biochemistry, Albert Einstein College of Medicine JoVE 63606 Biology आरएनए-बाइंडिंग क्षेत्रों की सामूहिक स्पेक्ट्रोमेट्री-आधारित पहचान के लिए नमूना तैयारी Robert Warneford-Thomson1,4, Chongsheng He1,2, Simone Sidoli1,3, Benjamin A. Garcia1,3, Roberto Bonasio1,2 1Epigenetics Institute, University of Pennsylvania Perelman School of Medicine, 2Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, 3Department of Biochemistry and Biophysics, University of Pennsylvania Perelman School of Medicine, 4Graduate Group in Biochemistry and Biophysics, University of Pennsylvania Perelman School of Medicine JoVE 56004 Biochemistry Histone बाद translational संशोधनों के विश्लेषण के लिए पूरा कार्यप्रवाह नीचे अप मास स्पेक्ट्रोमेट्री का उपयोग: Histone निकासी से डेटा विश्लेषण करने के लिए Simone Sidoli1, Natarajan V. Bhanu1, Kelly R. Karch1, Xiaoshi Wang1, Benjamin A. Garcia1 1Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania JoVE 54112 Biology
कार्यात्मक 3 डी स्फेरॉइड सेल संस्कृतियों का अर्ध-स्वचालित फेनोटाइपिक विश्लेषण Stephanie Stransky1, Dejauwne Young1, Karoline Mikkelsen2,3, Annemette Præstegaard Thulesen2, Helle Sedighi Frandsen3, Simone Sidoli1 1Department of Biochemistry, Albert Einstein College of Medicine, 2Department of Biochemistry and Molecular Biology, University of Southern Denmark, 3CelVivo ApS JoVE 65086 Biochemistry
हेपेटिक ऊतक के 3 डी सेल संस्कृति मॉडल में हिस्टोन पोस्ट-ट्रांसलेशनल संशोधनों का वैश्विक स्तर का परिमाणीकरण Jazmine-Saskya N. Joseph-Chowdhury1, Stephanie Stransky1, Sarah Graff1, Ronald Cutler1, Dejauwne Young1, Julie S. Kim1, Carlos Madrid-Aliste1, Jennifer T. Aguilan1, Edward Nieves1, Yan Sun1, Edwin J. Yoo1, Simone Sidoli1 1Department of Biochemistry, Albert Einstein College of Medicine JoVE 63606 Biology
आरएनए-बाइंडिंग क्षेत्रों की सामूहिक स्पेक्ट्रोमेट्री-आधारित पहचान के लिए नमूना तैयारी Robert Warneford-Thomson1,4, Chongsheng He1,2, Simone Sidoli1,3, Benjamin A. Garcia1,3, Roberto Bonasio1,2 1Epigenetics Institute, University of Pennsylvania Perelman School of Medicine, 2Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, 3Department of Biochemistry and Biophysics, University of Pennsylvania Perelman School of Medicine, 4Graduate Group in Biochemistry and Biophysics, University of Pennsylvania Perelman School of Medicine JoVE 56004 Biochemistry
Histone बाद translational संशोधनों के विश्लेषण के लिए पूरा कार्यप्रवाह नीचे अप मास स्पेक्ट्रोमेट्री का उपयोग: Histone निकासी से डेटा विश्लेषण करने के लिए Simone Sidoli1, Natarajan V. Bhanu1, Kelly R. Karch1, Xiaoshi Wang1, Benjamin A. Garcia1 1Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania JoVE 54112 Biology
