Stan Van de Graaf Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology Academic Medical Center Biography Publications Institution JoVE Articles Stan Van de Graaf has not added a biography. If you are Stan Van de Graaf and would like to personalize this page please email our Author Liaison for assistance. Publications ATP8B1-mediated Spatial Organization of Cdc42 Signaling Maintains Singularity During Enterocyte Polarization The Journal of Cell Biology. Sep, 2015 | Pubmed ID: 26416959 Impaired Uptake of Conjugated Bile Acids and Hepatitis B Virus Pres1-binding in Na(+) -taurocholate Cotransporting Polypeptide Knockout Mice Hepatology (Baltimore, Md.). Jul, 2015 | Pubmed ID: 25641256 Analysis of Aberrant Pre-messenger RNA Splicing Resulting from Mutations in ATP8B1 and Efficient in Vitro Rescue by Adapted U1 Small Nuclear RNA Hepatology (Baltimore, Md.). Apr, 2015 | Pubmed ID: 25421123 IgG4-associated Cholangitis: a Comprehensive Review Clinical Reviews in Allergy & Immunology. Jun, 2015 | Pubmed ID: 24958363 Fucosyltransferase 2: a Genetic Risk Factor for Primary Sclerosing Cholangitis and Crohn's Disease--a Comprehensive Review Clinical Reviews in Allergy & Immunology. Jun, 2015 | Pubmed ID: 24828903 Quantifying Stickiness: Thermodynamic Characterization of Intramolecular Domain Interactions to Guide the Design of Förster Resonance Energy Transfer Sensors Biochemistry. Oct, 2014 | Pubmed ID: 25216081 IgG4-associated Cholangitis Digestive Diseases (Basel, Switzerland). 2014 | Pubmed ID: 25034294 Autophagy - Another Piece of the Puzzle Towards Understanding Primary Biliary Cirrhosis? Liver International : Official Journal of the International Association for the Study of the Liver. Apr, 2014 | Pubmed ID: 24612169 Mutational Analysis of ATP8B1 in Patients with Chronic Pancreatitis PloS One. 2013 | Pubmed ID: 24260417 Early Adipogenesis is Regulated Through USP7-mediated Deubiquitination of the Histone Acetyltransferase TIP60 Nature Communications. 2013 | Pubmed ID: 24141283 Monitoring Bile Acid Transport in Single Living Cells Using a Genetically Encoded Förster Resonance Energy Transfer Sensor Hepatology (Baltimore, Md.). Feb, 2013 | Pubmed ID: 22899095 Natural Killer T Cells in Adipose Tissue Prevent Insulin Resistance The Journal of Clinical Investigation. Sep, 2012 | Pubmed ID: 22863618 Homo- and Hetero-dimeric Architecture of the Human Liver Na⁺-dependent Taurocholate Co-transporting Protein The Biochemical Journal. Feb, 2012 | Pubmed ID: 22029531 Familial Cholestasis: Progressive Familial Intrahepatic Cholestasis, Benign Recurrent Intrahepatic Cholestasis and Intrahepatic Cholestasis of Pregnancy Best Practice & Research. Clinical Gastroenterology. Oct, 2010 | Pubmed ID: 20955958 Heteromeric Interactions Required for Abundance and Subcellular Localization of Human CDC50 Proteins and Class 1 P4-ATPases The Journal of Biological Chemistry. Dec, 2010 | Pubmed ID: 20947505 Biochemical and Cellular Functions of P4 ATPases The Biochemical Journal. Oct, 2010 | Pubmed ID: 20836764 Folding Defects in P-type ATP 8B1 Associated with Hereditary Cholestasis Are Ameliorated by 4-phenylbutyrate Hepatology (Baltimore, Md.). Jan, 2010 | Pubmed ID: 19918981 Reduced Expression of ATP7B Affected by Wilson Disease-causing Mutations is Rescued by Pharmacological Folding Chaperones 4-phenylbutyrate and Curcumin Hepatology (Baltimore, Md.). Dec, 2009 | Pubmed ID: 19937698 Conditional Fast Expression and Function of Multimeric TRPV5 Channels Using Shield-1 American Journal of Physiology. Renal Physiology. Jan, 2009 | Pubmed ID: 18842822 TRPV5 is Internalized Via Clathrin-dependent Endocytosis to Enter a Ca2+-controlled Recycling Pathway The Journal of Biological Chemistry. Feb, 2008 | Pubmed ID: 18077461 Regulation of TRPV5 and TRPV6 by Associated Proteins American Journal of Physiology. Renal Physiology. Jun, 2006 | Pubmed ID: 16682485 Real Time Monitoring of Intracellular Bile Acid Dynamics Using a Genetically Encoded FRET-based Bile Acid Sensor Sandra Van de Wiel1, Maarten Merkx2,3, Stan Van de Graaf1 1Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Academic Medical Center, 2Laboratory of Chemical Biology, Institute of Complex Molecular Systems (ICMS), 3Department of Biomedical Engineering, Eindhoven University of Technology JoVE 53659 Bioengineering
Real Time Monitoring of Intracellular Bile Acid Dynamics Using a Genetically Encoded FRET-based Bile Acid Sensor Sandra Van de Wiel1, Maarten Merkx2,3, Stan Van de Graaf1 1Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Academic Medical Center, 2Laboratory of Chemical Biology, Institute of Complex Molecular Systems (ICMS), 3Department of Biomedical Engineering, Eindhoven University of Technology JoVE 53659 Bioengineering