Wenlei Jiang Food and Drug Administration (FDA) Center of Drug Evaluation Research - Office of Generic Drugs Biography Publications Institution JoVE Articles Wenlei Jiang has not added a biography. If you are Wenlei Jiang and would like to personalize this page please email our Author Liaison for assistance. Publications Effect of Common Excipients on the Oral Drug Absorption of Biopharmaceutics Classification System Class 3 Drugs Cimetidine and Acyclovir Journal of Pharmaceutical Sciences. Sep, 2015 | Pubmed ID: 26375604 The Effect of Excipients on the Permeability of BCS Class III Compounds and Implications for Biowaivers Pharmaceutical Research. Aug, 2015 | Pubmed ID: 26286187 Generic Lamotrigine Versus Brand-name Lamictal Bioequivalence in Patients with Epilepsy: A Field Test of the FDA Bioequivalence Standard Epilepsia. Sep, 2015 | Pubmed ID: 26201987 Biopharmaceutic Risk Assessment of Brand and Generic Lamotrigine Tablets Molecular Pharmaceutics. Jul, 2015 | Pubmed ID: 26001027 Erratum To: A Bioequivalence Approach for Generic Narrow Therapeutic Index Drugs: Evaluation of the Reference-Scaled Approach and Variability Comparison Criterion The AAPS Journal. Nov, 2015 | Pubmed ID: 25975618 A Bioequivalence Approach for Generic Narrow Therapeutic Index Drugs: Evaluation of the Reference-Scaled Approach and Variability Comparison Criterion The AAPS Journal. Jul, 2015 | Pubmed ID: 25840883 A PEGylation-Free Biomimetic Porphyrin Nanoplatform for Personalized Cancer Theranostics ACS Nano. Apr, 2015 | Pubmed ID: 25830219 Quantification of Lamotrigine in Patient Plasma Using a Fast Liquid Chromatography-tandem Mass Spectrometry Method with Backflush Technology Therapeutic Drug Monitoring. Apr, 2015 | Pubmed ID: 25162213 Role of Anti-inflammatory Compounds in Human Immunodeficiency Virus-1 Glycoprotein120-mediated Brain Inflammation Journal of Neuroinflammation. 2014 | Pubmed ID: 24884548 医薬品中のナノマテリアルの使用からの潜在的なリスクを評価する品評価リスク アセスメントの実習。 The AAPS Journal. Mar, 2013 | Pubmed ID: 23512727 Pathogenesis of Hepatic Encephalopathy and Brain Edema in Acute Liver Failure: Role of Glutamine Redefined Neurochemistry International. Jun, 2012 | Pubmed ID: 22382077 Systemic Oxidative Stress is Implicated in the Pathogenesis of Brain Edema in Rats with Chronic Liver Failure Free Radical Biology & Medicine. Apr, 2012 | Pubmed ID: 22300646 The Role of Predictive Biopharmaceutical Modeling and Simulation in Drug Development and Regulatory Evaluation International Journal of Pharmaceutics. Oct, 2011 | Pubmed ID: 21803144 In Vitro and in Vivo Characterizations of PEGylated Liposomal Doxorubicin Bioanalysis. Feb, 2011 | Pubmed ID: 21320053 Ammonia and Proinflammatory Cytokines Modify Expression of Genes Coding for Astrocytic Proteins Implicated in Brain Edema in Acute Liver Failure Metabolic Brain Disease. Mar, 2010 | Pubmed ID: 20217200 Portacaval Anastomosis-induced Hyperammonemia Does Not Lead to Oxidative Stress Metabolic Brain Disease. Mar, 2010 | Pubmed ID: 20195725 Minocycline Attenuates Oxidative/nitrosative Stress and Cerebral Complications of Acute Liver Failure in Rats Neurochemistry International. Dec, 2009 | Pubmed ID: 19524003 Hypothermia Attenuates Oxidative/nitrosative Stress, Encephalopathy and Brain Edema in Acute (ischemic) Liver Failure Neurochemistry International. Jul-Aug, 2009 | Pubmed ID: 19428816 Direct Evidence for Central Proinflammatory Mechanisms in Rats with Experimental Acute Liver Failure: Protective Effect of Hypothermia Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. May, 2009 | Pubmed ID: 19259110 Cerebral Inflammation Contributes to Encephalopathy and Brain Edema in Acute Liver Failure: Protective Effect of Minocycline Journal of Neurochemistry. Apr, 2009 | Pubmed ID: 19220703 Stabilization of Tetanus Toxoid Encapsulated in PLGA Microspheres Molecular Pharmaceutics. Sep-Oct, 2008 | Pubmed ID: 18710256 Anemia Upregulates Lipocalin 2 in the Liver and Serum Blood Cells, Molecules & Diseases. Sep-Oct, 2008 | Pubmed ID: 18519167 Distinct Requirements for Hfe in Basal and Induced Hepcidin Levels in Iron Overload and Inflammation American Journal of Physiology. Gastrointestinal and Liver Physiology. Aug, 2006 | Pubmed ID: 16565419 Contribution of Hfe Expression in Macrophages to the Regulation of Hepatic Hepcidin Levels and Iron Loading Blood. Sep, 2005 | Pubmed ID: 15914561 Effect of a Novel Inducible Nitric Oxide Synthase Inhibitor in Prevention of Rat Chronic Aortic Rejections Transplantation. May, 2005 | Pubmed ID: 15912108 Biodegradable Poly(lactic-co-glycolic Acid) Microparticles for Injectable Delivery of Vaccine Antigens Advanced Drug Delivery Reviews. Jan, 2005 | Pubmed ID: 15560948 Synergistic Effects of Malononitrilamides (FK778, FK779) with Tacrolimus (FK506) in Prevention of Acute Heart and Kidney Allograft Rejection and Reversal of Ongoing Heart Allograft Rejection in the Rat Transplantation. Jun, 2003 | Pubmed ID: 12811249 Combination Therapy of Malononitrilamide FK778 with Tacrolimus on Cell Proliferation Assays and in Rats Receiving Renal Allografts Transplantation. May, 2003 | Pubmed ID: 12792496 Synergistic Effect of Vincristine with Tacrolimus or Sirolimus in Prevention of Acute Heart Allograft Rejection in the Rat Microsurgery. 2003 | Pubmed ID: 12740883 Significant Prolongation of Renal Allograft Survival by Delayed Combination Therapy of FK778 with Tacrolimus in Nonhuman Primates Transplantation. Apr, 2003 | Pubmed ID: 12717189 Restoration of Fertility in Oophorectomized Rats After Tubo-ovarian Transplantation Microsurgery. 2002 | Pubmed ID: 11891873 LC-MS / MSを用いて乾燥血液スポット上で免疫抑制タクロリムスの定量化 Touraj Shokati1, Nicholas Bodenberger1, Holly Gadpaille1, Björn Schniedewind1, Alexander A. Vinks2, Wenlei Jiang3, Rita R. Alloway4, Uwe Christians1 1iC42 Clinical Research and Development, University of Colorado, Anschutz Medical Campus, 2Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, 3Food and Drug Administration (FDA), Center of Drug Evaluation Research - Office of Generic Drugs, 4Transplant Clinical Research, University of Cincinnati Medicine
LC-MS / MSを用いて乾燥血液スポット上で免疫抑制タクロリムスの定量化 Touraj Shokati1, Nicholas Bodenberger1, Holly Gadpaille1, Björn Schniedewind1, Alexander A. Vinks2, Wenlei Jiang3, Rita R. Alloway4, Uwe Christians1 1iC42 Clinical Research and Development, University of Colorado, Anschutz Medical Campus, 2Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, 3Food and Drug Administration (FDA), Center of Drug Evaluation Research - Office of Generic Drugs, 4Transplant Clinical Research, University of Cincinnati Medicine
