Yuntao Wu Center for Infectious Disease Research, School of Systems Biology George Mason University Biography Publications Institution JoVE Articles Yuntao Wu has not added a biography. If you are Yuntao Wu and would like to personalize this page please email our Author Liaison for assistance. Publications HIV Preintegration Transcription and Host Antagonism Current HIV Research. 2023 | Pubmed ID: 37345240 Suppressing Fatty Acid Synthase by Type I Interferon and Chemical Inhibitors As a Broad Spectrum Anti-viral Strategy Against SARS-CoV-2 Acta Pharmaceutica Sinica. B. Apr, 2022 | Pubmed ID: 35251918 Development of a Hybrid Alphavirus-SARS-CoV-2 Pseudovirion for Rapid Quantification of Neutralization Antibodies and Antiviral Drugs Cell Reports Methods. Mar, 2022 | Pubmed ID: 35229082 Exosomes Originating from Infection with the Cytoplasmic Single-stranded RNA Virus Rift Valley Fever Virus (RVFV) Protect Recipient Cells by Inducing RIG-I Mediated IFN-B Response That Leads to Activation of Autophagy Cell & Bioscience. Dec, 2021 | Pubmed ID: 34953502 Prestimulation of CD2 Confers Resistance to HIV-1 Latent Infection in Blood Resting CD4 T cells IScience. Nov, 2021 | Pubmed ID: 34765923 IP-10 Promotes Latent HIV Infection in Resting Memory CD4 T Cells LIMK-Cofilin Pathway Frontiers in Immunology. 2021 | Pubmed ID: 34447368 Identification of the SHREK Family of Proteins As Broad-Spectrum Host Antiviral Factors Viruses. May, 2021 | Pubmed ID: 34064525 A Traditional Medicine, Respiratory Detox Shot (RDS), Inhibits the Infection of SARS-CoV, SARS-CoV-2, and the Influenza A Virus in Vitro Cell & Bioscience. May, 2021 | Pubmed ID: 34051873 Targeted Delivery of Lopinavir to HIV Reservoirs in the Mesenteric Lymphatic System by Lipophilic Ester Prodrug Approach Journal of Controlled Release : Official Journal of the Controlled Release Society. Jan, 2021 | Pubmed ID: 33091528 PSGL-1 Inhibits the Incorporation of SARS-CoV and SARS-CoV-2 Spike Glycoproteins into Pseudovirions and Impairs Pseudovirus Attachment and Infectivity Viruses. Dec, 2020 | Pubmed ID: 33396594 Alterations of the Gut Bacterial Microbiota in Rhesus Macaques with SIV Infection and on Short- or Long-term Antiretroviral Therapy Scientific Reports. Nov, 2020 | Pubmed ID: 33149234 Conditionally Reprogrammed Human Normal Airway Epithelial Cells at ALI: A Physiological Model for Emerging Viruses Virologica Sinica. Jun, 2020 | Pubmed ID: 32557270 PSGL-1 Restricts HIV-1 Infectivity by Blocking Virus Particle Attachment to Target Cells Proceedings of the National Academy of Sciences of the United States of America. Apr, 2020 | Pubmed ID: 32273392 SARS-CoV-2 is an Appropriate Name for the New Coronavirus Lancet (London, England). Mar, 2020 | Pubmed ID: 32151324 Understanding SARS-CoV-2-Mediated Inflammatory Responses: From Mechanisms to Potential Therapeutic Tools Virologica Sinica. Jun, 2020 | Pubmed ID: 32125642 Compensation of ACE2 Function for Possible Clinical Management of 2019-nCoV-Induced Acute Lung Injury Virologica Sinica. Jun, 2020 | Pubmed ID: 32034638 Real-time Imaging of Individual Virion-triggered Cortical Actin Dynamics for Human Immunodeficiency Virus Entry into Resting CD4 T Cells Nanoscale. Jan, 2020 | Pubmed ID: 31773115 Relationships Between HIV-Mediated Chemokine Coreceptor Signaling, Cofilin Hyperactivation, Viral Tropism Switch and HIV-Mediated CD4 Depletion Current HIV Research. 2019 | Pubmed ID: 31702526 Proteomic Profiling of HIV-1 Infection of Human CD4 T Cells Identifies PSGL-1 As an HIV Restriction Factor Nature Microbiology. May, 2019 | Pubmed ID: 30833724 Cofilin Hyperactivation in HIV Infection and Targeting the Cofilin Pathway Using an Anti-αβ Integrin Antibody Science Advances. Jan, 2019 | Pubmed ID: 30662943 Tat Controls Transcriptional Persistence of Unintegrated HIV Genome in Primary Human Macrophages Virology. 05, 2018 | Pubmed ID: 29549786 AID Recruits the RNA Exosome to Degrade HIV-1 Nascent Transcripts Through Interaction with the Tat-P-TEFb-TAR RNP Complex FEBS Letters. Jan, 2018 | Pubmed ID: 29266200 Persistence of SIV in the Brain of SIV-infected Chinese Rhesus Macaques with or Without Antiretroviral Therapy Journal of Neurovirology. Feb, 2018 | Pubmed ID: 29181724 Elevated Interferon-γ-induced Protein 10 and Its Receptor CXCR3 Impair NK Cell Function During HIV Infection Journal of Leukocyte Biology. Jul, 2017 | Pubmed ID: 28465448 Discovery of Novel Small-Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1 Journal of Virology. Jul, 2017 | Pubmed ID: 28381571 Single-Particle Tracking of Human Immunodeficiency Virus Type 1 Productive Entry into Human Primary Macrophages ACS Nano. Apr, 2017 | Pubmed ID: 28371581 Flow Cytometry-Based Quantification of HIV-Induced T Cell Chemotactic Response Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 27271905 Real-Time Imaging of Single HIV-1 Disassembly with Multicolor Viral Particles ACS Nano. Jun, 2016 | Pubmed ID: 27253587 Therapeutic Doses of Irradiation Activate Viral Transcription and Induce Apoptosis in HIV-1 Infected Cells Virology. Nov, 2015 | Pubmed ID: 26184775 BRCA1 Functions As a Novel Transcriptional Cofactor in HIV-1 Infection Virology Journal. Mar, 2015 | Pubmed ID: 25879655 Bis-aryl Urea Derivatives As Potent and Selective LIM Kinase (Limk) Inhibitors Journal of Medicinal Chemistry. Feb, 2015 | Pubmed ID: 25621531 Chemokine Receptor CCR5 Antagonist Maraviroc: Medicinal Chemistry and Clinical Applications Current Topics in Medicinal Chemistry. 2014 | Pubmed ID: 25159165 Viral Exploitation of Actin: Force-generation and Scaffolding Functions in Viral Infection Virologica Sinica. Jun, 2014 | Pubmed ID: 24938714 HIV-1 Triggers WAVE2 Phosphorylation in Primary CD4 T Cells and Macrophages, Mediating Arp2/3-dependent Nuclear Migration The Journal of Biological Chemistry. Mar, 2014 | Pubmed ID: 24415754 Novel Anti-HIV Therapeutics Targeting Chemokine Receptors and Actin Regulatory Pathways Immunological Reviews. Nov, 2013 | Pubmed ID: 24117829 Genistein Interferes with SDF-1- and HIV-mediated Actin Dynamics and Inhibits HIV Infection of Resting CD4 T Cells Retrovirology. 2013 | Pubmed ID: 23782904 Inhibition of HIV Replication in Vitro by Clinical Immunosuppressants and Chemotherapeutic Agents Cell & Bioscience. May, 2013 | Pubmed ID: 23672887 The BET Bromodomain Inhibitor JQ1 Activates HIV Latency Through Antagonizing Brd4 Inhibition of Tat-transactivation Nucleic Acids Research. Jan, 2013 | Pubmed ID: 23087374 Involvement of LIM Kinase 1 in Actin Polarization in Human CD4 T Cells Communicative & Integrative Biology. Jul, 2012 | Pubmed ID: 23060964 HIV Gp120 is an Aberrant Chemoattractant for Blood Resting CD4 T Cells Current HIV Research. Dec, 2012 | Pubmed ID: 22954308 A Dichotomy in Cortical Actin and Chemotactic Actin Activity Between Human Memory and Naive T Cells Contributes to Their Differential Susceptibility to HIV-1 Infection The Journal of Biological Chemistry. Oct, 2012 | Pubmed ID: 22879601 The Trinity of the Cortical Actin in the Initiation of HIV-1 Infection Retrovirology. May, 2012 | Pubmed ID: 22640593 Study on the Luminescence and Energy Level of Lanthanide Ions in Lu(0.8)Sc(0.2)BO3 Host The Journal of Physical Chemistry. A. Dec, 2011 | Pubmed ID: 22026808 Spinoculation Triggers Dynamic Actin and Cofilin Activity That Facilitates HIV-1 Infection of Transformed and Resting CD4 T Cells Journal of Virology. Oct, 2011 | Pubmed ID: 21795326 LIM Kinase 1 Modulates Cortical Actin and CXCR4 Cycling and is Activated by HIV-1 to Initiate Viral Infection The Journal of Biological Chemistry. Apr, 2011 | Pubmed ID: 21321123 Effects of Microtubule Modulators on HIV-1 Infection of Transformed and Resting CD4 T Cells Journal of Virology. Mar, 2011 | Pubmed ID: 21209111 Control of the Differentiation of Regulatory T Cells and T(H)17 Cells by the DNA-binding Inhibitor Id3 Nature Immunology. Jan, 2011 | Pubmed ID: 21131965 Chemokine Control of HIV-1 Infection: Beyond a Binding Competition Retrovirology. 2010 | Pubmed ID: 20942936 Development of a Nonintegrating Rev-dependent Lentiviral Vector Carrying Diphtheria Toxin A Chain and Human TRAF6 to Target HIV Reservoirs Gene Therapy. Sep, 2010 | Pubmed ID: 20410930 Chemokine Coreceptor Signaling in HIV-1 Infection and Pathogenesis PLoS Pathogens. Dec, 2009 | Pubmed ID: 20041213 The HIV Envelope but Not VSV Glycoprotein is Capable of Mediating HIV Latent Infection of Resting CD4 T Cells PLoS Pathogens. Oct, 2009 | Pubmed ID: 19851458 Chemokine Receptor Signaling and HIV Infection Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19763976 Measurement of Human Immunodeficiency Virus Type 1 Preintegration Transcription by Using Rev-dependent Rev-CEM Cells Reveals a Sizable Transcribing DNA Population Comparable to That from Proviral Templates Journal of Virology. Sep, 2009 | Pubmed ID: 19553325 The Co-receptor Signaling Model of HIV-1 Pathogenesis in Peripheral CD4 T Cells Retrovirology. 2009 | Pubmed ID: 19409100 Cofilin Activation in Peripheral CD4 T Cells of HIV-1 Infected Patients: a Pilot Study Retrovirology. 2008 | Pubmed ID: 18928553 HIV Envelope-CXCR4 Signaling Activates Cofilin to Overcome Cortical Actin Restriction in Resting CD4 T Cells Cell. Sep, 2008 | Pubmed ID: 18775311 The Second Chance Story of HIV-1 DNA: Unintegrated? Not a Problem! Retrovirology. 2008 | Pubmed ID: 18613958 Selective Killing of HIV-1-positive Macrophages and T Cells by the Rev-dependent Lentivirus Carrying Anthrolysin O from Bacillus Anthracis Retrovirology. 2008 | Pubmed ID: 18439272 Human Macrophages Support Persistent Transcription from Unintegrated HIV-1 DNA Virology. Mar, 2008 | Pubmed ID: 18054979 Endogenous TGF-beta Activation by Reactive Oxygen Species is Key to Foxp3 Induction in TCR-stimulated and HIV-1-infected Human CD4+CD25- T Cells Retrovirology. 2007 | Pubmed ID: 17688698 Rev-dependent Indicator T Cell Line Current HIV Research. Jul, 2007 | Pubmed ID: 17627502 Rev-dependent Lentiviral Expression Vector Retrovirology. 2007 | Pubmed ID: 17286866 No Single Homologous Repeat Region is Essential for DNA Replication of the Baculovirus Autographa Californica Multiple Nucleopolyhedrovirus The Journal of General Virology. Jan, 2007 | Pubmed ID: 17170443 HIV-1 Gene Expression: Lessons from Provirus and Non-integrated DNA Retrovirology. 2004 | Pubmed ID: 15219234 Early Transcription from Nonintegrated DNA in Human Immunodeficiency Virus Infection Journal of Virology. Oct, 2003 | Pubmed ID: 12970422 Gene Transcription in HIV Infection Microbes and Infection / Institut Pasteur. Sep, 2003 | Pubmed ID: 12941394 Application of Ha-CoV-2 Pseudovirus for Rapid Quantification of SARS-CoV-2 Variants and Neutralizing Antibodies Linda Chilin1, Brian Hetrick1, Yuntao Wu1 1Center for Infectious Disease Research, School of Systems Biology, George Mason University JoVE 65793 Immunology and Infection Specific Marking of HIV-1 Positive Cells using a Rev-dependent Lentiviral Vector Expressing the Green Fluorescent Protein Jia Guo*1, Clinton Enos*1, Yuntao Wu1 1National Center for Biodefense and Infectious Diseases, Department of Molecular and Microbiology, George Mason University JoVE 2198 Immunology and Infection
Application of Ha-CoV-2 Pseudovirus for Rapid Quantification of SARS-CoV-2 Variants and Neutralizing Antibodies Linda Chilin1, Brian Hetrick1, Yuntao Wu1 1Center for Infectious Disease Research, School of Systems Biology, George Mason University JoVE 65793 Immunology and Infection
Specific Marking of HIV-1 Positive Cells using a Rev-dependent Lentiviral Vector Expressing the Green Fluorescent Protein Jia Guo*1, Clinton Enos*1, Yuntao Wu1 1National Center for Biodefense and Infectious Diseases, Department of Molecular and Microbiology, George Mason University JoVE 2198 Immunology and Infection