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JoVE Journal
Medicine

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新洲形成的助手依赖型腺病毒载体介导的基因转移对糖尿病小鼠肝
 
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新洲形成的助手依赖型腺病毒载体介导的基因转移对糖尿病小鼠肝

Article DOI: 10.3791/4321-v 16:59 min October 10th, 2012
October 10th, 2012

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Summary

Please note that all translations are automatically generated.

Click here for the English version.

我们描述了肝形成新胰岛STZ(链脲佐菌素)诱导的糖尿病小鼠的转基因Neurogenin3(Ngn3)和β细胞素(BTC)的使用依赖辅助腺病毒载体(HDAd)和反转高血糖。我们的方法的优点帮手依赖型腺病毒载体,其高度有效的体内转导和持久的基因表达。

Tags

医药,第68,遗传学,生理学,基因治疗,Neurogenin3,β细胞素,帮手依赖型腺病毒载体,1型糖尿病,胰岛新生
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