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JoVE Journal Medicine
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Organ Ischemia-Reperfusion Injury by Simulating Hemodynamic Changes in Rat Liver Transplant Model
Journal (Medicine)
Organ Ischemia-Reperfusion Injury by Simulating Hemodynamic Changes in Rat Liver Transplant Model
Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat
Journal (Medicine)
Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat
 
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Article DOI: 10.3791/52879-v • 08:46 min • December 9th, 2015
December 9th, 2015 •
1, 1, 1, 1, 2, 1, 1, 1, 1, 1
1H3 Biomedicine, 2Massachusetts General Hospital

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Geneesmiddelresistentie voor gerichte therapeutica is wijdverbreid en de noodzaak om resistentiemechanismen te identificeren - voor of na de eerste klinische verschijnselen - is essentieel voor het geleiden alternatieve klinische strategieën. Hier presenteren we een protocol te koppelen afleiding van resistente lijnen in vitro sequentiebepaling ontdekking van deze mechanismen te bespoedigen.

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Geneeskunde weerstand next-generation sequencing Moleculaire mechanismen, Xenograft Clones Kreeft
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